LOCUS       NM_001004282            1668 bp    mRNA    linear   ROD 11-DEC-2024
DEFINITION  Rattus norvegicus transmembrane protein 178A (Tmem178a), mRNA.
ACCESSION   NM_001004282 XM_343007
VERSION     NM_001004282.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1668)
  AUTHORS   Decker,C.E., Yang,Z., Rimer,R., Park-Min,K.H., Macaubas,C.,
            Mellins,E.D., Novack,D.V. and Faccio,R.
  TITLE     Tmem178 acts in a novel negative feedback loop targeting NFATc1 to
            regulate bone mass
  JOURNAL   Proc Natl Acad Sci U S A 112 (51), 15654-15659 (2015)
   PUBMED   26644563
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079338.1.
            
            On Sep 10, 2004 this sequence version replaced XM_343007.1.
            
            Sequence Note: This sequence has been modified as follows: removed
            30 bp suspected to be vector contamination from the 5' end.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079338.1, CK366007.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1668              BC079338.1         31-1698
FEATURES             Location/Qualifiers
     source          1..1668
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..1668
                     /gene="Tmem178a"
                     /gene_synonym="Tmem178"
                     /note="transmembrane protein 178A"
                     /db_xref="GeneID:362691"
                     /db_xref="RGD:1303057"
     exon            1..408
                     /gene="Tmem178a"
                     /gene_synonym="Tmem178"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..902
                     /gene="Tmem178a"
                     /gene_synonym="Tmem178"
                     /note="transmembrane protein 178"
                     /codon_start=1
                     /product="transmembrane protein 178A precursor"
                     /protein_id="NP_001004282.1"
                     /db_xref="GeneID:362691"
                     /db_xref="RGD:1303057"
                     /translation="MEPRALVTALSLGLSLCSLGLLVTAIFTDHWYETDPRRHKESCE
                     RSRAGADPPDQKNRLMPLSHLPLRDSPPLGRRLLPGGPGRSDPESWRSLLGLGGLDAE
                     CGRPLFATYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAVKYHFSQPIRLRNIPFNLT
                     KIIQQDEWHLLHLRRITAGFLGMAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTG
                     IFCTISLCTYAASVSYDLNRVPKLIYSLPHDVEHGYSWSIFCAWCSLGFIVAAGGLCI
                     AYPFISRTKIAHLKSGRDSTV"
     exon            409..522
                     /gene="Tmem178a"
                     /gene_synonym="Tmem178"
                     /inference="alignment:Splign:2.1.0"
     exon            523..660
                     /gene="Tmem178a"
                     /gene_synonym="Tmem178"
                     /inference="alignment:Splign:2.1.0"
     exon            661..1642
                     /gene="Tmem178a"
                     /gene_synonym="Tmem178"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggaagccat ggagccacgg gcgctcgtca cggcgctaag cctcggcctc agcctttgct
       61 ccctggggct gctcgtcacg gccatcttca ccgatcactg gtacgagacc gacccccggc
      121 gccacaagga gagctgcgag cgcagccgcg cgggcgccga ccccccggat cagaagaacc
      181 gcctgatgcc gctgtcgcac ctgccgctgc gggactcgcc tcccttgggg cgccggctgc
      241 tccccggcgg ccctgggcgc tctgacccgg agtcctggcg ctcgctgctg gggctcggtg
      301 ggttggacgc cgagtgtggc cggccgctgt tcgccaccta ctccggcctc tggaggaagt
      361 gctacttcct gggcatcgac cgggacatcg acaccctcat cctgaaaggt attgcacagc
      421 gatgcactgc ggtcaagtac cacttctctc agccaatccg cttacggaac attcctttca
      481 atttaaccaa gataatccag caagatgaat ggcacctgct tcatctaaga agaataacag
      541 ctggattcct gggcatggcg gtggctgtcc tgctgtgtgg ctgcatcgtg gccacggtca
      601 gcttcttctg ggaggaaagc ctgacccagc acgtggctgg actcctattc ctcatgacag
      661 ggatattttg caccatctca ctctgcacgt acgctgccag cgtctcctat gatttgaacc
      721 gggtcccaaa gctaatttac agcctgcctc atgatgtgga acatggctac agctggtcta
      781 tcttctgcgc ctggtgcagt ttaggcttta ttgtggcagc tggaggtctc tgcatcgctt
      841 atccgtttat tagccggacc aagattgcac atctaaagtc tggcagggac tccacggtat
      901 gactgcctgc atcgaagaag gcccagctac agagcggagc gggtctgagt tccattagga
      961 gcagtactga gttcacatca gggttccaag cacaaagagg tcttttacat tccaacctgt
     1021 tgcctgcagc cctttccgga tgactgactg gaaaccttgc agaacttccc aacctttcca
     1081 aggataagac aactgtgggt tcaagtgctt taatgactat ttatgctttg gttgagcgaa
     1141 gtgagcaacg ggctggagga catttgtagg catcagagaa gaggggcggc ggtggaaaaa
     1201 tttgtacgat ttccacttat ttcagaaagt ttgtatataa cgattacggg agagtcgttt
     1261 ctatttgtga aaggattcat gacaaaaacg agcataattt tcttgtcact gtgccaggct
     1321 tgttggactt taatgcagca tcttcagaac ttgtcctggt ggcgtcctgt tgtgtcagca
     1381 cctgatattt atgcattact tgtgaatgtt ccttgtcaca agaggattct ccttctgttg
     1441 ccttattatt acttttaatg aattgaagtc ccctctctgt ctttgtactg gagttcaaat
     1501 gcataagaat aacagaccaa ctgtgtaaga gctgatccgt aacactatgc agcatccttt
     1561 gaggtcttct ccgttccttg gcttgtgtct ctttatgtta actggatttc tgcattaaat
     1621 gactgccccc cttgttaatt taaaaaaaaa aaaaaaaaaa aaaaaaaa
//
