LOCUS       NM_001024298            1378 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane protein 174 (Tmem174), mRNA.
ACCESSION   NM_001024298 XM_574840
VERSION     NM_001024298.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1378)
  AUTHORS   Miyazaki-Anzai,S., Keenan,A.L., Blaine,J. and Miyazaki,M.
  TITLE     Targeted Disruption of a Proximal Tubule-Specific TMEM174 Gene in
            Mice Causes Hyperphosphatemia and Vascular Calcification
  JOURNAL   J Am Soc Nephrol 33 (8), 1477-1486 (2022)
   PUBMED   35459732
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079357.1.
            
            On May 27, 2005 this sequence version replaced XM_574840.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079357.1, CK481830.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1378
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q12"
     gene            1..1378
                     /gene="Tmem174"
                     /note="transmembrane protein 174"
                     /db_xref="GeneID:499516"
                     /db_xref="RGD:1561129"
     exon            1..653
                     /gene="Tmem174"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..759
                     /gene="Tmem174"
                     /codon_start=1
                     /product="transmembrane protein 174"
                     /protein_id="NP_001019469.1"
                     /db_xref="GeneID:499516"
                     /db_xref="RGD:1561129"
                     /translation="MEQSSNRPEDFPLNVFSVTPYTPSTADIQVSDDDKAGATLLFSG
                     IFLGLVGITFTVMGWIKYQGVSHFEWTQLLGPILLSVGVTFILISVCKFKMLSCQLCT
                     DNEERVLDSDQTSGGQSFVFTGINQPITFHGATVVQYIPPPYGSQEPLGMNTTYLQPM
                     MNPCGLVPSSGAVAATPSPPQYYTIYPQDNAAFVESEGFSPFVGAGHDRPSSDADQLE
                     GTQMGEEERVCFSPPPYEEIYALPR"
     exon            654..1352
                     /gene="Tmem174"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcacgttgg acagttgtgg aggagccatg gagcagagca gtaatcgccc agaggacttc
       61 ccgcttaacg tgttctccgt cactccgtac acacccagta ccgccgacat ccaggtgtcc
      121 gacgacgaca aggcgggggc caccttgctt ttctcaggga tctttctggg actggtgggg
      181 atcacattca ctgtcatggg ctggatcaag taccagggtg tctcccactt tgaatggacc
      241 cagctcctcg gacccatcct tctgtcggtc ggagtgacat tcatcctgat ctctgtgtgc
      301 aaattcaaaa tgttatcctg ccagttgtgc acagataacg aggaaagggt cctggactcg
      361 gaccagactt ccggaggaca gtcgttcgtt ttcaccggca tcaaccagcc catcaccttc
      421 cacggggcca ccgtggtgca gtatatccct cctccttatg gttctcagga gcccctggga
      481 atgaacacga cctacctgca gcccatgatg aacccttgcg gtctcgtacc ttctagcgga
      541 gcagtggctg ccacaccgag tcccccacag tactacacca tctaccctca agacaatgct
      601 gcgtttgtgg agagcgaggg cttctctcct ttcgtgggtg ctggtcatga caggcccagt
      661 tctgatgcag accagctaga agggacgcag atgggagagg aggaacgtgt gtgcttctct
      721 cctcccccct atgaggagat atacgcccta cctcgctaga gactgcaaag ctgtgggaac
      781 ggacatttca gccccgtgac gtgatacttg gagagttttc tgctgtaacc ttcagaagtt
      841 agatgccaaa gcagcccagg cgatcttaca gatgtcattc aaggtgggaa agaagtgtcc
      901 cgaggttgct aaattaagct gccctgggta aattcccctg tgctccagtt ttgaatcctc
      961 tgcatctggt agagtgattg tggagcatgc gcaatgcctt gggttcgatc ttgagaggca
     1021 gaaaacaaaa acgaaaacaa gacctctcta agtaaagtgc aggaagaaag ttcgcccgtt
     1081 tcccccatcc cccaccctat atccatttga aggtattagt gtcttagttt tatctgcaat
     1141 catggcagct ttcagactga cggaaggagg ctggtaagca agcagggaag agaataggtt
     1201 cagggagaaa cttccctgcc ccatgctgga ccttccacag cggagtgaat tatcccaaac
     1261 aacttgggct gtaatctggt ctccctttgg atcttaaaaa ctctgtaaaa aagaaataac
     1321 gaaatctctt gagaaataaa tgaataaaca gaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
