LOCUS       NP_001014076             697 aa            linear   ROD 03-APR-2024
DEFINITION  transmembrane protein 168 [Rattus norvegicus].
ACCESSION   NP_001014076 XP_231505
VERSION     NP_001014076.1
DBSOURCE    REFSEQ: accession NM_001014054.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 697)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (residues 1 to 697)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087124.1.
            
            On Apr 20, 2005 this sequence version replaced XP_231505.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087124.1, SRR8487231.160742.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..697
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q21"
     Protein         1..697
                     /product="transmembrane protein 168"
                     /calculated_mol_wt=79641
     Region          17..695
                     /region_name="TMEM168"
                     /note="Transmembrane (TMEM) protein family 168; cd21494"
                     /db_xref="CDD:411069"
     Region          35..57
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Site            36..56
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Region          63..85
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Site            63..83
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Site            89..109
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Region          92..109
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Site            111
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Region          170..192
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Site            172..192
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Site            199..219
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Region          199..216
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Site            223..243
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Region          226..248
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Region          261..283
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Site            265..285
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Site            293..313
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Region          298..320
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Site            337
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Site            352..372
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Region          359..378
                     /region_name="putative TM helix"
                     /note="putative TM helix [structural motif]"
                     /db_xref="CDD:411069"
     Site            380..400
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Site            533
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Site            598
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (Q5PQM0.1)"
     Site            646..666
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5PQM0.1)"
     CDS             1..697
                     /gene="Tmem168"
                     /gene_synonym="RGD1307778"
                     /coded_by="NM_001014054.1:326..2419"
                     /db_xref="GeneID:312135"
                     /db_xref="RGD:1307778"
ORIGIN      
        1 mckslrycfs hclylamtrl eevnrevnmh ssvrylgyla rfnllvaicl glyvrwekta
       61 nslilvifil glfvlgiasi lyyyfsmeaa slslsnlwfg fllgllcfld nssfksdvke
      121 ettkylllts ivlrilcalv erlsgyvrhr ptllttvefl elvgfaiast tmlverslsv
      181 illvmalaml iidlrmksfl aipnliifsv llffssletp qnpiafacff iclitdpfld
      241 iyfsglsvte rwkpflyrgr icrrlsvvft gmieltfftl safklrdthl wyfvipgfsi
      301 fgifwmichi iflltlwgfh tklndchkvy inhradnnsl drimaskgmr hfcliseqlv
      361 ffsllatail gavswqptng iflsmflivl plesmahglf helgnclggt svgyaivipt
      421 nfcspdgqpt llppehvqel nlrstgmlna iqrffayhmi etygcdysts glsfdtlhsk
      481 lkaflelrtv dgprhdtyvl yysghthgsg ewalaggdil rldtllewwr ekngsfcsrl
      541 iiildsenst pwvkevrkin dqyvavqgae laktvdieea dppqlgdftr dwveyncnst
      601 nnicwtekgr tvkamygvsk rwsdytlhlp tgsdvakhwm lhfpritypl vhlanwlcgl
      661 nlfwmckacf rclkrlkmsw flptvldtgq gfklvks
//
