LOCUS       NM_001135169             873 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane protein 14C (Tmem14c), transcript
            variant 2, mRNA.
ACCESSION   NM_001135169
VERSION     NM_001135169.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 873)
  AUTHORS   Yien,Y.Y., Robledo,R.F., Schultz,I.J., Takahashi-Makise,N.,
            Gwynn,B., Bauer,D.E., Dass,A., Yi,G., Li,L., Hildick-Smith,G.J.,
            Cooney,J.D., Pierce,E.L., Mohler,K., Dailey,T.A., Miyata,N.,
            Kingsley,P.D., Garone,C., Hattangadi,S.M., Huang,H., Chen,W.,
            Keenan,E.M., Shah,D.I., Schlaeger,T.M., DiMauro,S., Orkin,S.H.,
            Cantor,A.B., Palis,J., Koehler,C.M., Lodish,H.F., Kaplan,J.,
            Ward,D.M., Dailey,H.A., Phillips,J.D., Peters,L.L. and Paw,B.H.
  TITLE     TMEM14C is required for erythroid mitochondrial heme metabolism
  JOURNAL   J Clin Invest 124 (10), 4294-4304 (2014)
   PUBMED   25157825
REFERENCE   2  (bases 1 to 873)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB744788.1, BC158854.1 and CV107072.1.
            
            On Oct 9, 2008 this sequence version replaced NM_001135169.1.
            
            Transcript Variant: This variant (2) lacks a segment in the 5' UTR,
            compared to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ218209.1, FQ230083.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               CB744788.1         55-160
            107-417             BC158854.1         1-311
            418-873             CV107072.1         1-456               c
FEATURES             Location/Qualifiers
     source          1..873
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p12"
     gene            1..873
                     /gene="Tmem14c"
                     /gene_synonym="Cdtw1"
                     /note="transmembrane protein 14C"
                     /db_xref="GeneID:171432"
                     /db_xref="RGD:621692"
     exon            1..91
                     /gene="Tmem14c"
                     /gene_synonym="Cdtw1"
                     /inference="alignment:Splign:2.1.0"
     exon            92..150
                     /gene="Tmem14c"
                     /gene_synonym="Cdtw1"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..472
                     /gene="Tmem14c"
                     /gene_synonym="Cdtw1"
                     /note="P11 protein"
                     /codon_start=1
                     /product="transmembrane protein 14C"
                     /protein_id="NP_001128641.1"
                     /db_xref="GeneID:171432"
                     /db_xref="RGD:621692"
                     /translation="MQKDSGPLVPLHYYGFGYAALVATGGIIGYAKAGSVPSLAAGLF
                     FGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVA
                     KLGLSMLSSPHP"
     exon            151..227
                     /gene="Tmem14c"
                     /gene_synonym="Cdtw1"
                     /inference="alignment:Splign:2.1.0"
     exon            228..329
                     /gene="Tmem14c"
                     /gene_synonym="Cdtw1"
                     /inference="alignment:Splign:2.1.0"
     exon            330..417
                     /gene="Tmem14c"
                     /gene_synonym="Cdtw1"
                     /inference="alignment:Splign:2.1.0"
     exon            418..871
                     /gene="Tmem14c"
                     /gene_synonym="Cdtw1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgacgtctac acacccggct cctgacctct gttcctgtgc tcccgccgtc gtcctccagc
       61 gcaggcctcc gggctccagc tccggtgttg ggtgcaggcc tggtgtggtc tccaaagtga
      121 ctgaacaatg cagaaggaca gtggcccact ggttccttta cattattatg gtttcggcta
      181 tgcggccctg gtggctactg gtgggattat tggctatgca aaagcaggta gtgtgccgtc
      241 cctggctgct ggactcttct ttgggggcct ggcaggcctg ggtgcctacc agctgtctca
      301 ggaccccagg aacgtgtggg ttttcctagc tacgtctggg actttggctg gcattatggg
      361 gatgagattc tacaactctg ggaaatttat gcctgcaggt ttgatcgcgg gagccagttt
      421 gctgatggtt gccaaacttg gacttagtat gttgagttca ccccatccat agtagccata
      481 gccctgcgtg ggctcatgat gagttgacac tctccagtcc tccacattac cacgctgaag
      541 agataagaac agcaaagacc tacactgagc acatggaggc gaagacgtgg ttactatagt
      601 gaccattcag agacagcgag tgtctgacct cagagctcac actgccttca tgcggcttgt
      661 tcttgtgtca tgatgtctcg actctctgta ctactacata aaggggtaaa atgttgggtg
      721 tcaacactgg gggcccagag ctacacgtcc tgccgggaag ttgtgaaatc tcttggtgac
      781 atttgtgatg tgggatcttt tgcacaggtc tgctatgaaa ttatgttacg gcaacattat
      841 cggtgaaaat aaagttttct attaagaaca aaa
//
