LOCUS       NM_001107513            2191 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus transmembrane protein 143 (Tmem143), mRNA.
ACCESSION   NM_001107513 XM_001078112 XM_001079995 XM_001080005 XM_006229089
            XM_218573
VERSION     NM_001107513.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2191)
  AUTHORS   Nagamachi,A., Matsui,H., Asou,H., Ozaki,Y., Aki,D., Kanai,A.,
            Takubo,K., Suda,T., Nakamura,T., Wolff,L., Honda,H. and Inaba,T.
  TITLE     Haploinsufficiency of SAMD9L, an endosome fusion facilitator,
            causes myeloid malignancies in mice mimicking human diseases with
            monosomy 7
  JOURNAL   Cancer Cell 24 (3), 305-317 (2013)
   PUBMED   24029230
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Jul 30, 2021 this sequence version replaced
            XM_006229089.3, NM_001107513.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.2762498.1,
                                           SRR26360186.170399.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                JAXUCZ010000001.1  105508465-105508499
            36-267              JAXUCZ010000001.1  105508834-105509065
            268-372             JAXUCZ010000001.1  105510530-105510634
            373-567             JAXUCZ010000001.1  105516080-105516274
            568-698             JAXUCZ010000001.1  105517432-105517562
            699-978             JAXUCZ010000001.1  105518662-105518941
            979-1168            JAXUCZ010000001.1  105522990-105523179
            1169-2191           JAXUCZ010000001.1  105523397-105524419
FEATURES             Location/Qualifiers
     source          1..2191
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2191
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /note="transmembrane protein 143"
                     /db_xref="GeneID:308593"
                     /db_xref="RGD:1305013"
     exon            1..35
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..1389
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /codon_start=1
                     /product="transmembrane protein 143"
                     /protein_id="NP_001100983.1"
                     /db_xref="GeneID:308593"
                     /db_xref="RGD:1305013"
                     /translation="MTVARWLRLWEKGQAMLHVTWGSRVRVWSLVPALLGTPRALSSL
                     ENRMGAYRKMWNPKEPCNWAQQYRERFIPFSREQLLRLLIQEFHSSPAERAALEAFSA
                     HVDFCTLSHYHQLLARLQALYDPINPDRETLDQPSLTDPERLSSEKEVLQALKPLLAQ
                     ANFSPLSEDALAYALVVHHPQDEVQVTINLDQYIYIQFWALGQRVGQMPHKSSVGSKR
                     GFFRKLPPVERRYFKRVVLAARTKGGHLVLKSFKDTPLEGLEQLLPELKVRTPMMQRA
                     LLNLMLVVSGVVFFVNVGMVILSDLKMATSLLLLLFAAFMGIRASKVFGQRRSAQALE
                     LAHMLYYRSTSNNSELLSALALRAQEEHIKEALLAHSFLGRQPGGPQGTPEETSRWLQ
                     SEVESWLLAQSGCDVTFNGPRALAHLQALTPSFGLFPPPELPQLDPLVLGTPEAPQAA
                     LGSSYPSP"
     exon            36..267
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /inference="alignment:Splign:2.1.0"
     exon            268..372
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /inference="alignment:Splign:2.1.0"
     exon            373..567
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /inference="alignment:Splign:2.1.0"
     exon            568..698
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /inference="alignment:Splign:2.1.0"
     exon            699..978
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /inference="alignment:Splign:2.1.0"
     exon            979..1168
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..2191
                     /gene="Tmem143"
                     /gene_synonym="RGD1305013"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagaaggct caatgacagt cgcgcgctgg ctaaggctct gggaaaaggg gcaggccatg
       61 ttgcatgtga cctgggggtc cagggtccga gtatggtccc tggtgcctgc tctcctcggg
      121 actccccggg ctctgtcgtc cctggagaac aggatggggg cgtaccgcaa gatgtggaac
      181 cccaaggagc cctgcaactg ggcccagcag taccgcgagc gcttcattcc attctccagg
      241 gagcagctgc tccgcctcct gatacaggag ttccactcca gcccagcaga gagagcagct
      301 ttggaggcat tctcagctca tgtggacttc tgtaccctgt ctcactacca tcagctcctg
      361 gccaggctgc aggccttgta tgaccccatt aaccctgaca gggaaaccct ggaccagccg
      421 tcccttactg accctgagcg cctgtccagt gagaaggaag tgctccaggc tctgaagccc
      481 ctgctggccc aggccaactt ctctccactc tctgaagatg ccctggccta tgcacttgtc
      541 gtccatcacc ctcaggatga ggtccaggtg acaataaatt tggatcagta tatctacata
      601 cagttctggg ccttgggcca gagagttggg cagatgcccc acaagtccag tgtgggctcc
      661 aagcgtggct tcttcagaaa gttgccccct gtggagagga gatatttcaa gcgtgtggtg
      721 ctggcagccc ggacgaaagg agggcacctg gtcctgaaga gcttcaagga caccccactg
      781 gagggcttag agcagctgct gccggagctg aaggtgcgca cgcccatgat gcagcgcgcc
      841 ctgctcaacc tgatgctggt ggtctcgggc gttgtgttct tcgtcaacgt gggcatggtg
      901 atactgtctg acctcaagat ggccacctcc ctgctgctgc tgctcttcgc tgccttcatg
      961 ggcatcaggg cctccaaggt gtttgggcag cgccgtagcg cccaggccct ggagctggca
     1021 cacatgctgt actatcgaag cacatccaac aactcagaac tgctcagtgc cctggctctc
     1081 cgagcacagg aggaacacat caaggaagcc ctactggctc acagcttcct aggtcgccag
     1141 ccagggggcc cccaaggcac acctgaagag acctccaggt ggctgcagtc tgaagtggaa
     1201 agctggcttc tggcccagtc aggctgtgat gtaaccttca atggacctcg ggccctggcc
     1261 catctgcaag ccctgacccc cagctttgga ttgttcccac cacctgaatt gccacaactg
     1321 gacccgctgg tcctaggcac tccagaggcc ccgcaggctg cactgggtag tagctaccct
     1381 tcaccctgac cacttactac caggccctgc acagccaggg tgccaagctc cgcctcctcc
     1441 gtggcaagct gtcaatcgtg gcaactgcat ctccttcctg gactttcagt tgtttacagg
     1501 ctattatttc tgctaggcca ttaattttgc tatgctatag agttaagagt agccaatcag
     1561 ggctgctggc agttgctagg cagcctcctg aggccagcca atcaaagcca tttatttcgg
     1621 cttgttattt tatttcttag acccgtccct ggcgggaacc tcaccaaggt cggtggaaga
     1681 ggcggggcct ggggggagcg ggggagaggc tggacgcagc tgctggattg cagctgccag
     1741 ccttggccac actgagatgg gccaggctgt gaaagctgca ctgggaggcc ctgcttcgtc
     1801 atctgtttag cctgcacaga atggcccgcc acatgcacct gagcagggcc cactgcaacc
     1861 caagagctgt ttggttccgg tacacagtga gtgacagaca cagggcacct cagccacagg
     1921 cagccaatca gaatgtgtgg aggaacctcc tcagaatcca tgagatgagc catctgttct
     1981 gcagctgatc tgttctggtt ggaggcactg gaaacttctg gccccaaaaa agactttcag
     2041 gattccaccc caggattact ccagctcagg ccccagcagg ctcctaggcc tgctctgcct
     2101 tgctgtagaa atcacgttag cctgggtctc cctatctgta cactgtgtgt cacttcaccc
     2161 tcttccaaag gaataaatca tgcttaataa a
//
