LOCUS       NP_001401263            1073 aa            linear   ROD 31-MAR-2024
DEFINITION  transmembrane protein 132E precursor [Rattus norvegicus].
ACCESSION   NP_001401263 XP_008766187
VERSION     NP_001401263.1
DBSOURCE    REFSEQ: accession NM_001414334.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1073)
  AUTHORS   Li,J., Zhao,X., Xin,Q., Shan,S., Jiang,B., Jin,Y., Yuan,H., Dai,P.,
            Xiao,R., Zhang,Q., Xiao,J., Shao,C., Gong,Y. and Liu,Q.
  TITLE     Whole-exome sequencing identifies a variant in TMEM132E causing
            autosomal-recessive nonsyndromic hearing loss DFNB99
  JOURNAL   Hum Mutat 36 (1), 98-105 (2015)
   PUBMED   25331638
REFERENCE   2  (residues 1 to 1073)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 18, 2022 this sequence version replaced XP_008766187.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.62626.1,
                                           SRR21887623.2207906.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     Protein         1..1073
                     /product="transmembrane protein 132E precursor"
                     /calculated_mol_wt=114084
     sig_peptide     1..23
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2322
     Region          45..174
                     /region_name="TMEM132D_N"
                     /note="Mature oligodendrocyte transmembrane protein,
                     TMEM132D, N-term; pfam15705"
                     /db_xref="CDD:464813"
     Region          449..795
                     /region_name="TMEM132"
                     /note="Transmembrane protein family 132; pfam16070"
                     /db_xref="CDD:465003"
     Region          <875..940
                     /region_name="TMEM132D_C"
                     /note="Mature oligodendrocyte transmembrane protein,
                     TMEM132D, C-term; pfam15706"
                     /db_xref="CDD:464814"
     CDS             1..1073
                     /gene="Tmem132e"
                     /gene_synonym="RGD1565522"
                     /coded_by="NM_001414334.1:130..3351"
                     /db_xref="GeneID:287564"
                     /db_xref="RGD:1565522"
ORIGIN      
        1 mapgmlgrrg aallclsvll ahaasrshpa spsppgpqas pvlpvsyrls htrlafflke
       61 arpptptamn gslqrsepfv vfqtkelpvl nvslgpfsts qvvarellqp sstldiperl
      121 tvnwkvrafi vrarvpasqp vaqvlfyvag rdwddfgvte rlpcvrlhaf rdarevrssc
      181 rlggalatcl vraelplawf gppapaapps trrkspdgle peataesqqv elyytlhapd
      241 aaggcgsarr gsgpgpaara esptqhpllr igsislfrpp prramqehrl dsnlmirlpd
      301 rplrpgevls illylapnss saaspslehf tlrvkakkgv tllgtksrng qwhvtsellt
      361 gakhstatvd vawaqgtplp pwesqgplei lqldfemenf tsqsvkrrim whidyrghsa
      421 lpdleravte ltviqrdvqa ilplamdtei intailtgrt vaipvkviai evtgvvldvs
      481 dlvecqshre diikvssscd yvfvsgkesr gsmnarvtfr ydvlsaplem tvwvpklplh
      541 ielsdarlsq vkgwrvpilp drrsaresed eeeeeeerrq sanrgctlqy qhatlqvftq
      601 fhttssegte qvvtmlgpdw lvevtdlvsd fmrvgdprva hlvdsntlag lepgttpfkv
      661 vsplteavlg etlltvteek vsitqlqaqv vasltlslrp spgsshtila ttaaqptlss
      721 vkqeallslw lsysdgttap lslysprdyg llvnslderv atvtqdkafp llvaeaegag
      781 dllraeltis escqktkrks vlattpvglr vhfgrdeedp tydypgpsqp gpgggedear
      841 gagppgtaip agevpglgta gpmpptedfl plptgflqmp rgltdleigm yallgvfcla
      901 ilvflinciv fvlryrhkri ppegqtsmdh shhwvflgng qplrvqgels ppagsaletv
      961 pacchgdhhs sgssqtsvqs qvhgrgdgss ggsardqted passptskrk rvkfttfttl
     1021 pseelaydsv pageedeede edlgwgcpdv agttrptppp dlhnymrrik dia
//
