LOCUS       NM_001107155            2167 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus transmembrane protein 119 (Tmem119), mRNA.
ACCESSION   NM_001107155 XM_001080457 XM_222278
VERSION     NM_001107155.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2167)
  AUTHORS   Mizuhashi K, Chaya T, Kanamoto T, Omori Y and Furukawa T.
  TITLE     Obif, a Transmembrane Protein, Is Required for Bone Mineralization
            and Spermatogenesis in Mice
  JOURNAL   PLoS One 10 (7), e0133704 (2015)
   PUBMED   26207632
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2167)
  AUTHORS   Tanaka K, Inoue Y, Hendy GN, Canaff L, Katagiri T, Kitazawa R,
            Komori T, Sugimoto T, Seino S and Kaji H.
  TITLE     Interaction of Tmem119 and the bone morphogenetic protein pathway
            in the commitment of myoblastic into osteoblastic cells
  JOURNAL   Bone 51 (1), 158-167 (2012)
   PUBMED   22579779
REFERENCE   3  (bases 1 to 2167)
  AUTHORS   Mizuhashi K, Kanamoto T, Ito M, Moriishi T, Muranishi Y, Omori Y,
            Terada K, Komori T and Furukawa T.
  TITLE     OBIF, an osteoblast induction factor, plays an essential role in
            bone formation in association with osteoblastogenesis
  JOURNAL   Dev Growth Differ 54 (4), 474-480 (2012)
   PUBMED   22416756
REFERENCE   4  (bases 1 to 2167)
  AUTHORS   Hisa I, Inoue Y, Hendy GN, Canaff L, Kitazawa R, Kitazawa S, Komori
            T, Sugimoto T, Seino S and Kaji H.
  TITLE     Parathyroid hormone-responsive Smad3-related factor, Tmem119,
            promotes osteoblast differentiation and interacts with the bone
            morphogenetic protein-Runx2 pathway
  JOURNAL   J Biol Chem 286 (11), 9787-9796 (2011)
   PUBMED   21239498
REFERENCE   5  (bases 1 to 2167)
  AUTHORS   Kanamoto T, Mizuhashi K, Terada K, Minami T, Yoshikawa H and
            Furukawa T.
  TITLE     Isolation and characterization of a novel plasma membrane protein,
            osteoblast induction factor (obif), associated with osteoblast
            differentiation
  JOURNAL   BMC Dev Biol 9, 70 (2009)
   PUBMED   20025746
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473973.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_222278.4, XM_001080457.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166820.1, EV780451.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2167
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..2167
                     /gene="Tmem119"
                     /gene_synonym="RGD1307573"
                     /note="transmembrane protein 119"
                     /db_xref="GeneID:304581"
                     /db_xref="RGD:1307573"
     exon            1..118
                     /gene="Tmem119"
                     /gene_synonym="RGD1307573"
                     /inference="alignment:Splign:2.1.0"
     exon            119..2167
                     /gene="Tmem119"
                     /gene_synonym="RGD1307573"
                     /inference="alignment:Splign:2.1.0"
     CDS             134..985
                     /gene="Tmem119"
                     /gene_synonym="RGD1307573"
                     /note="transmembrane protein 119 homolog"
                     /codon_start=1
                     /product="transmembrane protein 119 precursor"
                     /protein_id="NP_001100625.1"
                     /db_xref="GeneID:304581"
                     /db_xref="RGD:1307573"
                     /translation="MVPCFLLSLLLLVRPAPVVAYSVSLPASFLEEVAGSGEAEGSSA
                     SSPSLLPPRTPAFSPTPGRTQPTAPVGPVPPTNLLDGIVDFFRQYVMLIAVVGSLTFL
                     IMFIVCAALITRQKHKATAYYPSSFPEKKYVDQRDRAGGPHAFSEVPDRAPDSRQEEG
                     LDSSQQLQADILAATQNLRSPARALPGSGEGTKQVKGGSEEEEEKEEEVFSGQEEPRE
                     APVCGVTEEKPEVPDETASAEAEGVPAASEGQGEPEGSFSLAQEPQGAAGPSERSCAC
                     NRISPNV"
ORIGIN      
        1 gccagagcag ctggcggcag acagtcggac cgagacagtt ggaccgagac agtcgaacgg
       61 tctaacaggg cctggcttgc ctacctggca gctgcacccg gtccttttcc cagagctggt
      121 tctgtgggtc aacatggtcc cctgcttcct cctgtctctg ctgctacttg tgaggcctgc
      181 gcctgtggtg gcctactctg tgtccctccc ggcctccttc ctggaggaag tggcgggcag
      241 tggggaagct gagggttctt cagcctcttc cccaagcctg ctgccgcccc ggactccagc
      301 cttcagtccc acaccaggga ggacccagcc cacagctccg gtcggccctg tgccacccac
      361 caacctcctg gatgggatcg tggacttctt ccgccagtat gtgatgctca ttgcggtggt
      421 gggctcgctg acctttctca tcatgttcat agtctgcgcg gcactcatca cgcgccagaa
      481 gcacaaggcc acagcctact acccgtcctc tttccccgaa aagaagtatg tggaccagag
      541 agaccgggct ggggggcccc atgccttcag cgaggtccct gacagggcac ctgacagccg
      601 gcaggaagag ggcctggact cctcccagca gctccaggct gacattctgg ctgctactca
      661 gaacctccgg tctccagcta gagccctgcc aggcagtggg gagggaacaa aacaggtgaa
      721 gggtgggtcg gaggaggagg aggagaagga agaggaggtg ttcagtggcc aggaggagcc
      781 ccgggaagcc ccagtatgtg gggtcactga agagaagccg gaggtccctg acgagacagc
      841 ctcagcagag gctgaagggg ttcccgcagc cagcgagggc caaggggaac cagaagggtc
      901 tttctcctta gcccaggaac cccagggagc agctggtcct tccgaaaggt cctgtgcctg
      961 caacagaatc tcccctaatg tgtaacaggc cccagaactg tgaggcctga ctcttgggtc
     1021 ctcgaaggtc acctccttgg tcaagaaagg cattcagctt tgactgcttc ttgacaccct
     1081 gccttggcca ttgtgggtgc caatcctgac cctgaatggg caaagctgct ggcctctggt
     1141 gtaccccagg aaacaccacc ccaagttcca gcgcccttaa tgactctcac catcctgggg
     1201 gcttcacccc gaagcaccac ttctctggaa ggggaaggtc agacacatcc cagttggagc
     1261 cgcaatgagg cagtcctcag aacagaaggg gaacaggcca gaggctgtct gtgacataca
     1321 cagtaaacac ccctgcttgc accttggctg tggagacaag aggggctgtt gattcagatg
     1381 ggcctgcggt gtcctctctg ccgttgtgcc ctgcaggata gcaaggtgca gtccgtgtct
     1441 ggtaatgcca gggactgcag agtccttcgc atctcctgat caccgcagtg tctctgtcac
     1501 gctgcccctg ttcagtggac ttgattagtt aggaagcttc tggaagggac ccctaattat
     1561 atcacggagt ttccccatgg aaacacaaac tccaaatcat gtgactttag gagccaccgt
     1621 gcccctccaa agactgacat ggctactcta agggttccca ctgggctggc tttgctacgc
     1681 tttcttcacg ttgcttcatt attaccagga ggtctcatag ctacaaagtc caatctcaca
     1741 gcacccagtc tggaaaacag tgttctcagg ttttctccaa ggcaccccac ttcctgattg
     1801 gttcagagtt ggaatgtggc acgcagggcg tccggctcac tcaagtgtca agtgaccctg
     1861 acttgggtgt gtgcaagaca tcttgctgtc aatgctgggg tgagggagaa gccaagggga
     1921 tgtttggggg tcacagccat tctggattct gacacccagc ctggagcagg ggcctggccc
     1981 attctacgct cacacagtgg tctagcagcc tgaacccaca ccgttcctca accctcaaca
     2041 gtgctgaggc tctgtcctgt tggggatttt ggggttcact acacctgcat tcagggctcc
     2101 ccgagatgtc agctcttcag gtgtggatat atgacacact agcataataa accttgatct
     2161 ggcttga
//
