LOCUS       NM_001166165            1511 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane protein 11 (Tmem11), transcript
            variant 2, mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001166165
VERSION     NM_001166165.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1511)
  AUTHORS   Rival,T., Macchi,M., Arnaune-Pelloquin,L., Poidevin,M., Maillet,F.,
            Richard,F., Fatmi,A., Belenguer,P. and Royet,J.
  TITLE     Inner-membrane proteins PMI/TMEM11 regulate mitochondrial
            morphogenesis independently of the DRP1/MFN fission/fusion pathways
  JOURNAL   EMBO Rep 12 (3), 223-230 (2011)
   PUBMED   21274005
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC158725.1 and DY316208.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and
            coding sequence compared to variant 1. The resulting isoform (2)
            has a shorter and distinct N-terminus compared to isoform 1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DY316208.1, FM058133.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-257               BC158725.1         1-257
            258-890             DY316208.1         1-633
            891-1511            BC158725.1         604-1224
FEATURES             Location/Qualifiers
     source          1..1511
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..1511
                     /gene="Tmem11"
                     /gene_synonym="RGD1309817"
                     /note="transmembrane protein 11"
                     /db_xref="GeneID:303196"
                     /db_xref="RGD:1309817"
     exon            1..305
                     /gene="Tmem11"
                     /gene_synonym="RGD1309817"
                     /inference="alignment:Splign:2.1.0"
     exon            306..592
                     /gene="Tmem11"
                     /gene_synonym="RGD1309817"
                     /inference="alignment:Splign:2.1.0"
     CDS             579..1109
                     /gene="Tmem11"
                     /gene_synonym="RGD1309817"
                     /note="isoform 2 is encoded by transcript variant 2;
                     transmembrane protein 11, mitochondrial"
                     /codon_start=1
                     /product="transmembrane protein 11, mitochondrial isoform
                     2"
                     /protein_id="NP_001159637.1"
                     /db_xref="GeneID:303196"
                     /db_xref="RGD:1309817"
                     /translation="MIVGMVSLSATDCYIVHEIYSGENAQDQFEYELEQALEAQYKYI
                     VIEPTRIGDETARWITVGNCLHKTAVLAGTACLFTPLALPLDYSHYISLPAGVLSLAC
                     CTLYGISWQFDPCCKYQVEYDAYKLSRLPLHTLTSSTPVVLVRKDDLHRKRLHNTIAL
                     AALVYCVKKVYELYAV"
     exon            593..1486
                     /gene="Tmem11"
                     /gene_synonym="RGD1309817"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgtccaggcg gtgggctcag cgactcgcac tttgcgactc ggagactctt tcctcaggcg
       61 gagcccacct ctcgccctct tgcgcgcggc agcttacagt aggcttccgg cgtgaggcat
      121 tgtgggcagt agagtccgct cgcaacctcc caacgcggac gcgcggctca ccggactacg
      181 tttcccttcg gcctgcgcgc gccccgagcc gcgtcggctc cagcccccga cgaaccgaga
      241 gtctccaaga tggccgcgtg gggaaggagg cgtctgggtc cgggcggcgg cagctcccga
      301 gagagggaaa caacagtatt tgtaatgaag aacatcaaac tctgagctgt aacctgaatt
      361 cttgtccaaa attgagcata ctgacagcaa gcacagcaaa cagattgcgt ttgtcctgct
      421 ggcctctttg aggcccactt acccacctag gaaagcagag caggtatccg tattccacca
      481 cctgtgccag cttggaccag ctctcagaca gccctgccta tccttccctg ggctacttgg
      541 tgctgctctc agagcccctg agcatctctg agatctccat gattgttgga atggttagcc
      601 tgtcagctac agattgctac attgtgcatg agatctacag tggggagaat gcccaggacc
      661 agtttgagta tgagctggag caggcgctgg aagcccagta caagtacatt gtgatagagc
      721 ccacccggat tggagacgag acagcacgct ggatcaccgt aggcaattgc ctgcacaaga
      781 cggccgtgtt ggcaggtact gcctgcctct tcaccccatt ggcactgccc ctggattact
      841 cccactacat ctccctgccc gctggtgtgc tgagcctggc ctgctgtacc ctctatggga
      901 tctcctggca gtttgaccct tgctgcaagt accaggtgga gtatgatgcc tataaactgt
      961 cccgcctgcc tctgcacacg ctcacctcct ccacaccagt ggtgctggtt cggaaggacg
     1021 acctgcacag aaagagactg cacaacacaa tagccctggc tgccctggtg tactgtgtaa
     1081 agaaggttta tgagctctac gccgtatgac tgcaggagag tgggacgaga agcagaacca
     1141 cagggcccac aggactcaga ttccctacag caacactggg ttttctctgt gaagcagcag
     1201 cacctgggaa agtgtttggt ttaatacttg ttattttttt aagcaaaaat aacagatcat
     1261 gggtgtgcca ggggtttcag ctcattacac taagatgtct atttccataa cccaggagtg
     1321 gctcccaggc tgtggaagtc tgactgagca gtggaatatg gatagagcca atgctacttt
     1381 ttgaggggta tgaacttgct gtgggggtgt cttaagtata ttgtttaact ataccattca
     1441 gaagccaacc ggaagctatt gaccattaaa attatgagaa tttcaaaaaa aaaaaaaaaa
     1501 aaaaaaaaaa a
//
