LOCUS       NM_001399273            3681 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus transmembrane protein 108 (Tmem108), mRNA.
ACCESSION   NM_001399273 XM_039082600
VERSION     NM_001399273.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3681)
  AUTHORS   Jiao,H.F., Sun,X.D., Bates,R., Xiong,L., Zhang,L., Liu,F., Li,L.,
            Zhang,H.S., Wang,S.Q., Xiong,M.T., Patel,M., Stranahan,A.M.,
            Xiong,W.C., Li,B.M. and Mei,L.
  TITLE     Transmembrane protein 108 is required for glutamatergic
            transmission in dentate gyrus
  JOURNAL   Proc Natl Acad Sci U S A 114 (5), 1177-1182 (2017)
   PUBMED   28096412
REFERENCE   2  (bases 1 to 3681)
  AUTHORS   Xu,C., Fu,X., Zhu,S. and Liu,J.J.
  TITLE     Retrolinkin recruits the WAVE1 protein complex to facilitate
            BDNF-induced TrkB endocytosis and dendrite outgrowth
  JOURNAL   Mol Biol Cell 27 (21), 3342-3356 (2016)
   PUBMED   27605705
REFERENCE   3  (bases 1 to 3681)
  AUTHORS   Fu,X., Yang,Y., Xu,C., Niu,Y., Chen,T., Zhou,Q. and Liu,J.J.
  TITLE     Retrolinkin cooperates with endophilin A1 to mediate BDNF-TrkB
            early endocytic trafficking and signaling from early endosomes
  JOURNAL   Mol Biol Cell 22 (19), 3684-3698 (2011)
   PUBMED   21849472
REFERENCE   4  (bases 1 to 3681)
  AUTHORS   Liu,J.J., Ding,J., Wu,C., Bhagavatula,P., Cui,B., Chu,S.,
            Mobley,W.C. and Yang,Y.
  TITLE     Retrolinkin, a membrane protein, plays an important role in
            retrograde axonal transport
  JOURNAL   Proc Natl Acad Sci U S A 104 (7), 2223-2228 (2007)
   PUBMED   17287360
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Jan 5, 2022 this sequence version replaced XM_039082600.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.360539.1,
                                           SRR26643295.33203.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-77                JAXUCZ010000008.1  113238847-113238923 c
            78-190              JAXUCZ010000008.1  113230088-113230200 c
            191-276             JAXUCZ010000008.1  113071864-113071949 c
            277-1686            JAXUCZ010000008.1  112959635-112961044 c
            1687-1841           JAXUCZ010000008.1  112950363-112950517 c
            1842-3681           JAXUCZ010000008.1  112944928-112946767 c
FEATURES             Location/Qualifiers
     source          1..3681
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..3681
                     /gene="Tmem108"
                     /gene_synonym="RGD1311530"
                     /note="transmembrane protein 108"
                     /db_xref="GeneID:300967"
                     /db_xref="RGD:1311530"
     exon            1..77
                     /gene="Tmem108"
                     /gene_synonym="RGD1311530"
                     /inference="alignment:Splign:2.1.0"
     exon            78..190
                     /gene="Tmem108"
                     /gene_synonym="RGD1311530"
                     /inference="alignment:Splign:2.1.0"
     exon            191..276
                     /gene="Tmem108"
                     /gene_synonym="RGD1311530"
                     /inference="alignment:Splign:2.1.0"
     CDS             237..1964
                     /gene="Tmem108"
                     /gene_synonym="RGD1311530"
                     /codon_start=1
                     /product="transmembrane protein 108 precursor"
                     /protein_id="NP_001386202.1"
                     /db_xref="GeneID:300967"
                     /db_xref="RGD:1311530"
                     /translation="MKRSLQALYCQLLSFLLTLALTKALVLAVQGPSPRESLQTLPSG
                     SPPGTMVTATHSPTRLSSVMTLSPKPDGRSSQAAATMETTVSHPEGHPPTDTVSTVMV
                     TAAVPHPESPLPTGSPPAAMATTSSHSESRPPGDDAPAATTLPTKPAGTTTRPTVSPR
                     VPTRRPPRPPGSSRKGTGGSSRTFPLVPGGHSARKESQRGRNQSSTHLGPKRPLGKIF
                     QIYKGNFTGSVEPDPSALTPRTPLGGYFSSTQPQTVSPATGPRSTSWVPPTTSLVPAT
                     DKPDLTRANQGSGPTFTSPGGEPDATAASGAPDSTQPAPVPSRSPHGDVQDSSSHSDS
                     WLAVTPDTDRPTSASSRVFTAATGPTQAAFDASVSAPPPGIPQGPSATPPAPAWPSGV
                     SESIVSPAKEEAEASPTTTDRGPRPLSTVPSTATGNFLNRLVPAGTWKPGTVANISHV
                     AEGDKPQHRATICLSKMDIAWVILAISVPISSCSVLLTVCCMRRKKKTANPENNLSYW
                     NNAITMDYFNRHAVELPREIQSLETSEDQLSEPRSPANGDYRDTGMVLVNPFCQETLF
                     VGNDQVSEI"
     exon            277..1686
                     /gene="Tmem108"
                     /gene_synonym="RGD1311530"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1841
                     /gene="Tmem108"
                     /gene_synonym="RGD1311530"
                     /inference="alignment:Splign:2.1.0"
     exon            1842..3681
                     /gene="Tmem108"
                     /gene_synonym="RGD1311530"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagagcgcga gtgcgcgtgc gcgagcggcg gggctttctc cggagccgtc ggagggagcc
       61 ggagcgcttc tcccgagatc gcttagctgt ggtccagcat gcagaagtga gcgtgtggtg
      121 aaaggcagca gacccaatgg gttgcgagga tgtaagagtg tttgaaggct tccacaccct
      181 ctcctccagg gcagaatcat gaataaactg gaggacaagc aggaccagat gataccatga
      241 agagaagttt acaggccctc tattgccaac tgttaagctt tctcctaacc ttggcactga
      301 ccaaagcact ggtactcgcc gtccagggac catctcccag ggaatctctg cagaccctcc
      361 cctcaggcag ccccccaggc accatggtga cagcaactca cagccctacc agactctcct
      421 ctgtgatgac cctgagccct aaacctgatg gccgctcatc acaggctgca gctactatgg
      481 aaacgacagt atctcatcca gaagggcacc ctcccacaga cactgtgtcc acagtgatgg
      541 tgacagctgc cgtcccccat cctgaaagcc ctctgcccac aggttcccct ccagctgcca
      601 tggcaaccac atcgtcccac tcagagagcc gccccccagg ggatgatgcc cctgccgcca
      661 ccaccctgcc aacaaagcca gcaggaacca ccacccgccc cacagtgtcc ccacgggtcc
      721 caactcgtag gccccccagg cccccaggct cttccaggaa ggggactggt ggctcgtctc
      781 gcactttccc acttgtaccc ggtggccact cagcaaggaa ggaaagccag aggggacgaa
      841 atcagagctc aacacatctg gggccgaagc gtcctctggg gaagatattc caaatctaca
      901 aaggtaactt tacggggtct gtggagccag acccctctgc tctcactccc aggaccccac
      961 tcgggggcta cttctcttcg acacagcctc agacagtatc tccagctaca ggacccagaa
     1021 gcacctcgtg ggtgcccccc acaacttccc tggtacctgc aacggacaag ccagacctta
     1081 ccagagccaa ccaggggagt ggccccacat ttaccagccc aggaggggag ccagatgcca
     1141 cagcagcttc aggtgcccct gacagtacac agcccgcccc agtgccttct cggagccctc
     1201 atggtgacgt gcaagacagc tccagccaca gtgactcttg gcttgctgtc acccctgaca
     1261 ctgacagacc cacgtctgcc agctccaggg tcttcacggc tgccacgggg cccacccagg
     1321 ctgccttcga tgccagtgtc tcagcccctc ccccgggcat ccctcaggga ccatctgcaa
     1381 cccctccggc cccagcctgg ccctctgggg tctcagaaag tattgtttct ccagcaaagg
     1441 aagaggctga ggcctccccc acaaccaccg acagggggcc cagaccgctt tccacagtgc
     1501 cgtctacagc cacgggcaac ttcctcaacc gcctggtccc cgcggggacc tggaagccgg
     1561 gaactgtggc caacatctcc catgtggctg aaggggacaa gccccagcac agagccacca
     1621 tctgcctgag caagatggat attgcctggg tcatcttggc catcagtgtg cccatctctt
     1681 cctgctccgt cctgttgaca gtgtgctgta tgagaaggaa gaagaagaca gccaaccctg
     1741 agaacaacct gagctactgg aacaacgcca tcaccatgga ctacttcaac agacatgccg
     1801 tggagctccc gagggagatc cagtccctag agacctcaga ggaccagctc tcagagcccc
     1861 gctccccagc caatggcgac taccgagaca ctgggatggt cctcgtgaac cccttctgcc
     1921 aggaaacact gttcgtggga aacgaccaag tttctgagat ctagatgcag cagcctccgc
     1981 tttgccactc cctatttttg tccctaaatt ataaatatac aaatatatat attataaata
     2041 taacctttgt gtaaccccga cttaataaga gacattttca gctttttttc ttaagaattg
     2101 tcaacatctt ttttacaagt gtggtttaaa aaaaaaattt acagaacgac cccatggctt
     2161 tataaaataa aggtatttct aagcaaagcg gctgcaccaa ttgcttctct taactgatct
     2221 gggcatggag aggttccagg agccctgggc aggtgaggaa agagaccagt ctccctcgga
     2281 agctgaacgt tagtgtggcc aaatgagtgg ccatctgtgt ggtcttggtg ctctggttcc
     2341 cttgactcag tgtgcccacc tgccctgtct ttttgtattt tttcccctag tggtgggaac
     2401 tggggcacca gggcagaaga ctcaggcaag tatacaaaac tgtcttgtca gcctggagcc
     2461 tcactctacc gtcactgaat gtcagtgaaa gccatcagga ggccccggcc cccttttctg
     2521 accccacaga tgttcccacc atgctagaag aaacaggact gctgcctttg tctggcagaa
     2581 aagtggtccc tagaaaccct tctcagcatc ccttccagca ccacacctgc ctcggacccc
     2641 atgcttcctc ccttcctaga ggacagacgc acatctcagc ctaggggctg tgcagctcct
     2701 acttgccctt ccctgtccag gggtccggtg tttgttggga ttctctactg ctttctccaa
     2761 aggcaatgat cttgtgcccc tgagaaacag gtttatctag aaagccttgt ggtgtagaac
     2821 tatttttttt aacctccccc cattaaatct ttaaagaaag agattgccaa atgaatcact
     2881 tgaaagaagt gccactctgt ctccaggcag aagcacggca gacctgccca caaactcgcc
     2941 atgccatcct ctttcactgt cccctgcctc cccttctctt gttcccctgg gtccaggtcc
     3001 agctgccatc ccagcccaca ctgtacccag tttgaccaac aaggaacaga ctctcagaac
     3061 cccaagaggg gctttctggg tccaatcgct tttctctgtt actttcctaa cccaccatgg
     3121 ctagggattt aacttcaacc cctctcccct tctctaaaag aaaaatagtt tgatagtata
     3181 ttttgaatat agatgttctt attatcagat tggagcttga atttgactgt tgattcgatg
     3241 tctgtgttgt tgctgtggtc ttctttatca taactgcctc ttttcttcca tccccccgtt
     3301 ccaaaagaac gacggccttc aaaactcatg tgtgttctca atgttctatg gacctaccta
     3361 acacgagtct gcttgtctct cttcaaagac ttcaacccac aaagaagcag gttaaatgtt
     3421 gtgccgagat cttgctctct accatgttgc tgtctgacct taaccttatc atgatatttc
     3481 tgttagctac tgcattgaat atgccaatgt gtgtgagtat gtattgagaa aaacatgttt
     3541 gtaaagtaaa atttatatat aatatatgtc atcacagata catatgttat atatatacat
     3601 ttgtggatgt atgacttatt ttccgtatcc acagaattca gctaccatgt atatataaat
     3661 aaacttattt tattacccag a
//
