LOCUS       NM_001109648            1038 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus transmembrane protein 107 (Tmem107), mRNA.
ACCESSION   NM_001109648 XM_001078195 XM_001078214 XM_001078229
VERSION     NM_001109648.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Shylo,N.A., Christopher,K.J., Iglesias,A., Daluiski,A. and
            Weatherbee,S.D.
  TITLE     TMEM107 Is a Critical Regulator of Ciliary Protein Composition and
            Is Mutated in Orofaciodigital Syndrome
  JOURNAL   Hum Mutat 37 (2), 155-159 (2016)
   PUBMED   26518474
REFERENCE   2  (bases 1 to 1038)
  AUTHORS   Lambacher,N.J., Bruel,A.L., van Dam,T.J., Szymanska,K.,
            Slaats,G.G., Kuhns,S., McManus,G.J., Kennedy,J.E., Gaff,K.,
            Wu,K.M., van der Lee,R., Burglen,L., Doummar,D., Riviere,J.B.,
            Faivre,L., Attie-Bitach,T., Saunier,S., Curd,A., Peckham,M.,
            Giles,R.H., Johnson,C.A., Huynen,M.A., Thauvin-Robinet,C. and
            Blacque,O.E.
  TITLE     TMEM107 recruits ciliopathy proteins to subdomains of the ciliary
            transition zone and causes Joubert syndrome
  JOURNAL   Nat Cell Biol 18 (1), 122-131 (2016)
   PUBMED   26595381
REFERENCE   3  (bases 1 to 1038)
  AUTHORS   Christopher,K.J., Wang,B., Kong,Y. and Weatherbee,S.D.
  TITLE     Forward genetics uncovers Transmembrane protein 107 as a novel
            factor required for ciliogenesis and Sonic hedgehog signaling
  JOURNAL   Dev Biol 368 (2), 382-392 (2012)
   PUBMED   22698544
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001078195.1, XM_001078229.1, XM_001078214.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..1038
                     /gene="Tmem107"
                     /note="transmembrane protein 107"
                     /db_xref="GeneID:691750"
                     /db_xref="RGD:1595972"
     exon            1..218
                     /gene="Tmem107"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..554
                     /gene="Tmem107"
                     /codon_start=1
                     /product="transmembrane protein 107"
                     /protein_id="NP_001103118.1"
                     /db_xref="GeneID:691750"
                     /db_xref="RGD:1595972"
                     /translation="MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPE
                     EYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIF
                     ERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF"
     exon            219..286
                     /gene="Tmem107"
                     /inference="alignment:Splign:2.1.0"
     exon            287..387
                     /gene="Tmem107"
                     /inference="alignment:Splign:2.1.0"
     exon            388..484
                     /gene="Tmem107"
                     /inference="alignment:Splign:2.1.0"
     exon            485..1038
                     /gene="Tmem107"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcaaccg ggcggcgcct gagcacgcgg gaaggaggct taagtagaga ggtctggcct
       61 gcttgctctg ggagacttga tgagtgaccc tcctcagact tctacggcct ccgctttggg
      121 cccccgaggc catgggtcgg atctccgggc tcgtgccctc tcgattcctg acgctcttgg
      181 ctcatctggt gattgtcatc actttgttct ggtcccggga aagcaacatc caggcttgcc
      241 tgcctctcaa gttcaccccg gaggaatatg agaagcagga caaccaactg gtagcagcgc
      301 tctgcctcac cctgggcctc tttgcagtgg agctggctgg cttcctctca ggagtctcca
      361 tgtttaatag cacccagagc ctcctctcca ttgcagccca ctgtagcgcg tctgtggccc
      421 tatctttctt catattcgag cgatgggaat gtaccacgta ctggtacatt tttgccttct
      481 gcagcgcttt tccagctgtc actgaaactg cgttattcat cgctgtcttt gggctgaaaa
      541 agaaaccctt ctgatcacaa tccgatgaag agaccaaagc cggaaacgtg atgaactccc
      601 tcccattgct ggaagaagaa agggagaggc ttcagttttc tctcgcccta gtcttttgct
      661 cctcccaact gcgtctaaac agaaaatggc aatgttggga taagatctca caaatcttgg
      721 gttataattt tattagagtt ttgtaataaa attcatttta taataagagc aaggcttaga
      781 ctatttgtca gaagaccatt gggtaaatca aaaggctgat gtaaataaag gcttttttct
      841 agccttctgt acgtgagcta gtagcttatg cttctatttg gatttttacg gtacaaaata
      901 ggcggaagtg agtgggcggg aatatgtaaa taagaacctc acatagggct tctaatttgc
      961 tgtatgtgag cggagcatta tgggagaact ttgtttctct ctttctgcgc cgaatggaaa
     1021 aataaaatat ttcaggcg
//
