LOCUS       NM_023020               2506 bp    mRNA    linear   ROD 04-FEB-2024
DEFINITION  Rattus norvegicus transmembrane protein with EGF-like and two
            follistatin-like domains 1 (Tmeff1), mRNA.
ACCESSION   NM_023020 XM_001055768
VERSION     NM_023020.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2506)
  AUTHORS   Gery,S., Yin,D., Xie,D., Black,K.L. and Koeffler,H.P.
  TITLE     TMEFF1 and brain tumors
  JOURNAL   Oncogene 22 (18), 2723-2727 (2003)
   PUBMED   12743596
REFERENCE   2  (bases 1 to 2506)
  AUTHORS   Eib,D.W., Holling,T.M., Zwijsen,A., Dewulf,N., de Groot,E., van den
            Eijnden-van Raaij,A.J., Huylebroeck,D. and Martens,G.J.
  TITLE     Expression of the follistatin/EGF-containing transmembrane protein
            M7365 (tomoregulin-1) during mouse development
  JOURNAL   Mech Dev 97 (1-2), 167-171 (2000)
   PUBMED   11025219
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC129093.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by NM_023020.3.
            
            On Jan 10, 2007 this sequence version replaced NM_023020.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC129093.1, AJ250730.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2506
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..2506
                     /gene="Tmeff1"
                     /note="transmembrane protein with EGF-like and two
                     follistatin-like domains 1"
                     /db_xref="GeneID:63845"
                     /db_xref="RGD:62005"
     exon            1..483
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     CDS             309..1430
                     /gene="Tmeff1"
                     /note="tomoregulin-1; TR-1; transmembrane protein with
                     EGF-like and one follistatin-like domain"
                     /codon_start=1
                     /product="tomoregulin-1 precursor"
                     /protein_id="NP_075409.1"
                     /db_xref="GeneID:63845"
                     /db_xref="RGD:62005"
                     /translation="MGAQAPLRLPAAPPLAVCGYTSVLLLFAFCLPGSGASNQPAGGG
                     GDCPGGRGKSINCSELNLRESDIRACDESSCKYGGVCKEDGDGLKCACQFQCHTNYIP
                     VCGSNGDTYQNECFLRRAACKHQKDITVVARGPCYSDNGSGSGEGEEEGSGAGAHRKH
                     SKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIRQE
                     QIDIRHLGHCTDTDDTSLLGKKDDGLQYRPDVKDAGDQREDVYIGSHMPCPENLNGYC
                     IHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQI
                     AIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSETSSRMV"
     exon            484..593
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     exon            594..723
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     exon            724..750
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     exon            751..847
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     exon            848..996
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1062
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1186
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1345
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
     exon            1346..2482
                     /gene="Tmeff1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgacggccgc gcggacacaa agggaaggcg agcctgcgag ctagaggctg cgtccgtccc
       61 cgccccgcgc cccccgcgcg cgccccagct ccgtgttccc cacgcggcgc gctccctggc
      121 ctcgcgcgcc cgcgcccctc gcccgcgccg gggtccccca acgaggctgt cccgagcgcg
      181 gagggccggg gcctggcggg gatgctgcgg ggctgccccg ggcggcggca cggctgctag
      241 gaggcggcac ggggccggtg tgcccggcct gccgctccct gagctccccg ccgtgcgtcc
      301 gcgacagcat gggcgcccag gcgccgctcc ggctgccggc cgcgcccccg ctcgccgtct
      361 gcggctacac gtcggtgctt ctgctcttcg ccttctgcct gcccgggagc ggcgcgtcca
      421 accagcccgc gggcggcggc ggggactgtc ccggaggcag aggcaagagc atcaactgct
      481 cagaattaaa tctgagagaa tctgacatcc gagcgtgtga tgaatcatcg tgtaagtatg
      541 gaggtgtctg caaagaagac ggagatggtt tgaaatgcgc atgccagttt cagtgccata
      601 caaattacat tcctgtctgt ggatcaaacg gggacactta ccagaatgag tgttttctca
      661 ggagggctgc ttgcaagcac cagaaagaca taacagtggt ggcacgtgga ccttgctact
      721 ctgataacgg ctctggatct ggagaaggag aggaggaagg ctcaggagcc ggggctcaca
      781 ggaagcattc caagtgtgga ccgtgcaagt acaaggctga gtgtgacgag gatgcggaaa
      841 acgttgggtg tgtgtgtaac atagactgca gcgggtacag ctttaacccg gtgtgtgctt
      901 ccgatgggag ttcctataac aatccctgtt tcgttcgaga agcgtcttgt ataaggcaag
      961 aacagatcga cataaggcac cttggccact gcacagacac agatgacaca agtttgttgg
     1021 gaaagaagga tgacgggctg cagtatcggc cagatgtgaa agatgctggt gatcaaaggg
     1081 aagatgttta tatcggaagc cacatgcctt gccctgaaaa cctcaatggg tactgcatcc
     1141 acgggaagtg tgaattcatc tactctactc agaaggcctc ttgtagatgc gaatctggtt
     1201 atactggaca gcactgtgag aagacggact ttagtattct ctatgtagtg ccaagtaggc
     1261 agaagctcac ccatgttctt atcgcagcca ttattggagc agtacagatc gccattatag
     1321 tagcaattgt catgtgcata acaagaaaat gccccaagaa caacagagga cgacggcaga
     1381 agcaaaacct aggtcacttt acttcagaga cttcatccag gatggtttga gctgctgact
     1441 tttatatgca cactgaccac gtgatgtaca tttattatgt ctttttttaa agaatggaaa
     1501 tatttatttc agaggcctta tttttggaca tttttagtgt agtactgttg gctcgtattt
     1561 agaatattca gctacaacag tttttgactg tttagtagtc tccgtcttat gtttttaaat
     1621 atggaaattg gctccacgga tttgtaacac atggtaatac taagacttgc tctttatcca
     1681 tggaatgtaa tatttttgca gagacggatg gacccacttc atagtcgtta taaagtcata
     1741 ctttcttccc caatgaccac agcaaatgac aaagcatgaa ctaaaagtaa agatgtttac
     1801 agattacttt tcttacaaaa aagaaaaaaa atctagagga cactgtgttt aaatagatat
     1861 tcaaatgttt tttgagattt agtacctggt tttttttaga tacttcccct attgcatgag
     1921 ctgcaaagct gtgtgtgtgt tagatgtaac atatttataa gctgaacgaa ctggaactga
     1981 ccatttctct ctttggagaa gtaatcctaa taattttaaa aggtacctgg gaattaacaa
     2041 tggaacagat cgttgaaaat agacttagat attgtcaaga tagggtgttt taatgagcag
     2101 atcgggagaa aacctacagt atcagttaaa ctactttaat gcgcgttcat ttttaaacat
     2161 tgtatctgtt ttcatataaa tgtacaaatt gtatcagtgt ttgtgaatac aacgcagaaa
     2221 taattgttga tgatcggtgc tctgaaagcg agcttaaaaa atgacctaag acctctaatt
     2281 cgaatctgtc ctgcagtagc tctattaata gattgttggt gtttaaaagt ctgagctgtg
     2341 agtagaatgt tatcgaggtg tttaatgtgt agtttagcca gtcaaaatta tgcatgtaga
     2401 atttaaagac tatgtttaaa cttaaatatt aattttaata atttgatttg gaaaagcatg
     2461 ttataatata atgttttcac taaaaaaaaa aaaaaaaaaa aaaaaa
//
