LOCUS       NM_001009703            1446 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane p24 trafficking protein 9 (Tmed9),
            mRNA.
ACCESSION   NM_001009703 XM_341489
VERSION     NM_001009703.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1446)
  AUTHORS   Liu,L., Fujino,K. and Nishimura,M.
  TITLE     Pre-synaptic localization of the gamma-secretase-inhibiting protein
            p24alpha2 in the mammalian brain
  JOURNAL   J Neurochem 133 (3), 422-431 (2015)
   PUBMED   25438880
REFERENCE   2  (bases 1 to 1446)
  AUTHORS   Muppirala,M., Gupta,V. and Swarup,G.
  TITLE     Syntaxin 17 cycles between the ER and ERGIC and is required to
            maintain the architecture of ERGIC and Golgi
  JOURNAL   Biol Cell 103 (7), 333-350 (2011)
   PUBMED   21545355
REFERENCE   3  (bases 1 to 1446)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   4  (bases 1 to 1446)
  AUTHORS   Cao,Z., Li,C., Higginbotham,J.N., Franklin,J.L., Tabb,D.L.,
            Graves-Deal,R., Hill,S., Cheek,K., Jerome,W.G., Lapierre,L.A.,
            Goldenring,J.R., Ham,A.J. and Coffey,R.J.
  TITLE     Use of fluorescence-activated vesicle sorting for isolation of
            Naked2-associated, basolaterally targeted exocytic vesicles for
            proteomics analysis
  JOURNAL   Mol Cell Proteomics 7 (9), 1651-1667 (2008)
   PUBMED   18504258
REFERENCE   5  (bases 1 to 1446)
  AUTHORS   Mitrovic,S., Ben-Tekaya,H., Koegler,E., Gruenberg,J. and Hauri,H.P.
  TITLE     The cargo receptors Surf4, endoplasmic reticulum-Golgi intermediate
            compartment (ERGIC)-53, and p25 are required to maintain the
            architecture of ERGIC and Golgi
  JOURNAL   Mol Biol Cell 19 (5), 1976-1990 (2008)
   PUBMED   18287528
REFERENCE   6  (bases 1 to 1446)
  AUTHORS   Jenne,N., Frey,K., Brugger,B. and Wieland,F.T.
  TITLE     Oligomeric state and stoichiometry of p24 proteins in the early
            secretory pathway
  JOURNAL   J Biol Chem 277 (48), 46504-46511 (2002)
   PUBMED   12237308
REFERENCE   7  (bases 1 to 1446)
  AUTHORS   Barr,F.A., Preisinger,C., Kopajtich,R. and Korner,R.
  TITLE     Golgi matrix proteins interact with p24 cargo receptors and aid
            their efficient retention in the Golgi apparatus
  JOURNAL   J Cell Biol 155 (6), 885-891 (2001)
   PUBMED   11739402
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088422.1.
            
            On Jan 13, 2005 this sequence version replaced XM_341489.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088422.1, FQ219234.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1446
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1446
                     /gene="Tmed9"
                     /gene_synonym="RGD1307627"
                     /note="transmembrane p24 trafficking protein 9"
                     /db_xref="GeneID:361207"
                     /db_xref="RGD:1307627"
     exon            1..188
                     /gene="Tmed9"
                     /gene_synonym="RGD1307627"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..712
                     /gene="Tmed9"
                     /gene_synonym="RGD1307627"
                     /note="transmembrane emp24 domain-containing protein 9;
                     p24alpha2; p24 family protein alpha-2; transmembrane emp24
                     protein transport domain containing 9"
                     /codon_start=1
                     /product="transmembrane emp24 domain-containing protein 9
                     precursor"
                     /protein_id="NP_001009703.1"
                     /db_xref="GeneID:361207"
                     /db_xref="RGD:1307627"
                     /translation="MAAVRGVRVVGTSPGLLLGRGMRAFLLLLCLAARGGALYFHIGE
                     TEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQY
                     GSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDK
                     LSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIG
                     VWQMRHLKSFFEAKKLV"
     exon            189..289
                     /gene="Tmed9"
                     /gene_synonym="RGD1307627"
                     /inference="alignment:Splign:2.1.0"
     exon            290..415
                     /gene="Tmed9"
                     /gene_synonym="RGD1307627"
                     /inference="alignment:Splign:2.1.0"
     exon            416..562
                     /gene="Tmed9"
                     /gene_synonym="RGD1307627"
                     /inference="alignment:Splign:2.1.0"
     exon            563..1419
                     /gene="Tmed9"
                     /gene_synonym="RGD1307627"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caagatggct gcggtgcgag gcgtgcgagt tgtcggaacc tcacctggac tcttgctggg
       61 gagagggatg cgggccttcc tgctactgct gtgccttgca gcccgcggag gcgcgctcta
      121 tttccacata ggagagacag agaagaagtg cttcattgag gagattccgg acgagaccat
      181 ggtcatcgga aattaccgga cgcagctgta tgacaaacag cgggaggagt accagccagc
      241 cactcctggg cttggtatgt tcgtggaagt aaaagacccc gaggacaagg tcattctggc
      301 ccggcagtat ggctctgagg gcaggttcac attcacctcc cacacccccg gtgagcacca
      361 gatctgtctt cactcaaatt ctaccaagtt ctccctcttt gctggaggga tgctgagagt
      421 tcaccttgac atccaagtgg gcgaacacgc gaacgactat gcggaaatcg cggccaaaga
      481 caagctgagt gagctgcagc tgagagtccg acagctggtg gagcaggtgg agcagatcca
      541 aaaggagcag aactaccagc ggtggcgaga ggagcgcttc agacaaacca gcgaaagcac
      601 caaccagcga gtgctgtggt ggtccatcct acagactctc atcctcgtgg ccatcggcgt
      661 ctggcagatg cggcacctca agagcttttt tgaagccaag aagttggtgt agctgtccca
      721 agcctcacag gcaatctttc ttccaggctg tgggaaaagg acctggagcc agttcctctc
      781 tgggaggaca actggttttc agccatagat gttctggagg agagagggac tgcaatcatg
      841 tccccgttcc tcaggctcaa gtggaggacg gcaaccggct ggctaatgct aagcaggcag
      901 tgggaccagc cttccccacc tccacctctg gaccttctgc agtaatcact cgggggctgg
      961 tgatgccctt ggtgtctcag tgttactgat cagggatgtg ggttgctgtc tggggtaggt
     1021 ttcgggaggg acgtgggtgg gccagcaagc tgattttcct tgtcttcctt tgttaatgtg
     1081 ggattttgag caggtcaggg tgcatcagtg actccttgct attccagaaa cttgcttttc
     1141 ctgcctttgg cttagaacca gcctgctaac ctaaggtgtg tttgtgtgtc agtttaaggg
     1201 cgtggagggg ttgcagtgca cgaaaggggc ccagaggttg attttagttt ctcacggttg
     1261 tccttttggg gcttgagcag ccggtatcaa accaagcaga gactttggtg ctggttggag
     1321 acagagccta cagagtctta gttactgagt ttattttcaa tgagtgtggg tttgttacat
     1381 tggtttccca attaaaaaaa aaaaaagatg aagaagaaaa aaaaaaaaaa aaaaaaaaaa
     1441 aaaaaa
//
