LOCUS       NM_053467               1314 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus transmembrane p24 trafficking protein 10
            (Tmed10), mRNA.
ACCESSION   NM_053467
VERSION     NM_053467.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1314)
  AUTHORS   Del Olmo,T., Lacarriere-Keita,C., Normandin,C., Jean,D.,
            Boisvert,F.M. and Jean,S.
  TITLE     RAB21 interacts with TMED10 and modulates its localization and
            abundance
  JOURNAL   Biol Open 8 (9) (2019)
   PUBMED   31455601
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1314)
  AUTHORS   Osiecka-Iwan,A., Niderla-Bielinska,J., Hyc,A. and Moskalewski,S.
  TITLE     Rat chondrocyte-associated antigen identified as sialylated
            transmembrane protein Tmp21 belonging to the p24 protein family
  JOURNAL   Calcif Tissue Int 94 (3), 348-352 (2014)
   PUBMED   24271503
  REMARK    GeneRIF: chondrocyte-associated antigen Tmp21 may be considered a
            chondrocyte differentiation antigen
REFERENCE   3  (bases 1 to 1314)
  AUTHORS   Muppirala,M., Gupta,V. and Swarup,G.
  TITLE     Syntaxin 17 cycles between the ER and ERGIC and is required to
            maintain the architecture of ERGIC and Golgi
  JOURNAL   Biol Cell 103 (7), 333-350 (2011)
   PUBMED   21545355
REFERENCE   4  (bases 1 to 1314)
  AUTHORS   Teranishi,Y., Hur,J.Y., Welander,H., Franberg,J., Aoki,M.,
            Winblad,B., Frykman,S. and Tjernberg,L.O.
  TITLE     Affinity pulldown of gamma-secretase and associated proteins from
            human and rat brain
  JOURNAL   J Cell Mol Med 14 (11), 2675-2686 (2010)
   PUBMED   19754663
REFERENCE   5  (bases 1 to 1314)
  AUTHORS   Bonnon,C., Wendeler,M.W., Paccaud,J.P. and Hauri,H.P.
  TITLE     Selective export of human GPI-anchored proteins from the
            endoplasmic reticulum
  JOURNAL   J Cell Sci 123 (Pt 10), 1705-1715 (2010)
   PUBMED   20427317
REFERENCE   6  (bases 1 to 1314)
  AUTHORS   Gommel,D., Orci,L., Emig,E.M., Hannah,M.J., Ravazzola,M.,
            Nickel,W., Helms,J.B., Wieland,F.T. and Sohn,K.
  TITLE     p24 and p23, the major transmembrane proteins of COPI-coated
            transport vesicles, form hetero-oligomeric complexes and cycle
            between the organelles of the early secretory pathway
  JOURNAL   FEBS Lett 447 (2-3), 179-185 (1999)
   PUBMED   10214941
REFERENCE   7  (bases 1 to 1314)
  AUTHORS   Bremser,M., Nickel,W., Schweikert,M., Ravazzola,M., Amherdt,M.,
            Hughes,C.A., Sollner,T.H., Rothman,J.E. and Wieland,F.T.
  TITLE     Coupling of coat assembly and vesicle budding to packaging of
            putative cargo receptors
  JOURNAL   Cell 96 (4), 495-506 (1999)
   PUBMED   10052452
REFERENCE   8  (bases 1 to 1314)
  AUTHORS   Blum,R., Pfeiffer,F., Feick,P., Nastainczyk,W., Kohler,B.,
            Schafer,K.H. and Schulz,I.
  TITLE     Intracellular localization and in vivo trafficking of p24A and p23
  JOURNAL   J Cell Sci 112 (Pt 4), 537-548 (1999)
   PUBMED   9914165
REFERENCE   9  (bases 1 to 1314)
  AUTHORS   Xu,D.G., Crocker,S.J., Doucet,J.P., St-Jean,M., Tamai,K.,
            Hakim,A.M., Ikeda,J.E., Liston,P., Thompson,C.S., Korneluk,R.G.,
            MacKenzie,A. and Robertson,G.S.
  TITLE     Elevation of neuronal expression of NAIP reduces ischemic damage in
            the rat hippocampus
  JOURNAL   Nat Med 3 (9), 997-1004 (1997)
   PUBMED   9288726
REFERENCE   10 (bases 1 to 1314)
  AUTHORS   Blum,R., Feick,P., Puype,M., Vandekerckhove,J., Klengel,R.,
            Nastainczyk,W. and Schulz,I.
  TITLE     Tmp21 and p24A, two type I proteins enriched in pancreatic
            microsomal membranes, are members of a protein family involved in
            vesicular trafficking
  JOURNAL   J Biol Chem 271 (29), 17183-17189 (1996)
   PUBMED   8663407
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ004912.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ004912.1, EV777471.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1314
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     gene            1..1314
                     /gene="Tmed10"
                     /gene_synonym="Tmp21"
                     /note="transmembrane p24 trafficking protein 10"
                     /db_xref="GeneID:84599"
                     /db_xref="RGD:620970"
     CDS             1..660
                     /gene="Tmed10"
                     /gene_synonym="Tmp21"
                     /note="transmembrane emp24 domain-containing protein 10;
                     transmembrane protein Tmp21; 21 kDa
                     transmembrane-trafficking protein; transmembrane
                     emp24-like trafficking protein 10; integral membrane
                     protein Tmp21-I (p23); transmembrane trafficking protein
                     21; p24delta1; p24 family protein delta-1"
                     /codon_start=1
                     /product="transmembrane emp24 domain-containing protein 10
                     precursor"
                     /protein_id="NP_445919.1"
                     /db_xref="GeneID:84599"
                     /db_xref="RGD:620970"
                     /translation="MSGLSGPLSWPGPLLSALLFLFLLGPSSVLGISFHLPVNSRKCL
                     REEIHKDLLVTGAYEITDQSGGAGGLRTHLKITDSAGHILYAKEDATKGKFAFTTEDY
                     DMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSES
                     IVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLI
                     E"
     exon            1..225
                     /gene="Tmed10"
                     /gene_synonym="Tmp21"
                     /inference="alignment:Splign:2.1.0"
     exon            226..337
                     /gene="Tmed10"
                     /gene_synonym="Tmp21"
                     /inference="alignment:Splign:2.1.0"
     exon            338..411
                     /gene="Tmed10"
                     /gene_synonym="Tmp21"
                     /inference="alignment:Splign:2.1.0"
     exon            412..538
                     /gene="Tmed10"
                     /gene_synonym="Tmp21"
                     /inference="alignment:Splign:2.1.0"
     exon            539..1288
                     /gene="Tmed10"
                     /gene_synonym="Tmp21"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtctggtt tgtctggccc actatcctgg cctggccctc tcctatccgc cttgctcttt
       61 ctgttccttc tcggccccag ctcggtcctc ggcatctcct tccatctacc cgtgaactct
      121 cgcaagtgtc tccgcgagga gatccacaaa gacttgctgg ttacgggcgc gtacgagatc
      181 accgaccagt ctgggggcgc tggcggcctg cgcacccacc tcaagatcac agattctgct
      241 ggccatattc tgtatgccaa agaggatgca actaaaggga agtttgcctt taccacagaa
      301 gactatgaca tgtttgaagt atgctttgag agcaagggaa cagggcggat acctgaccaa
      361 ctagtgattc tagacatgaa gcatggagta gaggcgaaaa attatgaaga gatcgcaaaa
      421 gttgagaaac tcaaaccact ggaggtggag ctacggcgcc tcgaggacct ttcagagtct
      481 attgttaacg actttgccta catgaagaag cgggaagagg agatgaggga caccaacgag
      541 tccacaaaca cccgcgtcct gtacttcagc atcttttcca tgttctgcct cattggacta
      601 gccacctggc aggtcttcta cctgcgtcgc ttcttcaagg ccaagaagtt gatagagtaa
      661 tgaggctcag tcttctgtcc cctggagcca gcagaacatc gctgggacgt gcctggccta
      721 gcccaaggcc aagttactaa cagtatatca aggcgcacgt gagcatcttg ccagaactga
      781 tccttctggt gtgggagagc atgggcacca cccacaccca gcaagtcaga gaggactttt
      841 taatgcagta ggatttggac tggtttgcaa caagattatt aaagtcgcct atggaaaaac
      901 aaaacaaaac aaaacaacaa acaggggtta cctagataac gccaaagcca gcattcgtcc
      961 tgggtcgcct cacaggatcg gtttgagctg tttgcttttt ctctcccact tgctcaccgc
     1021 cttggtcctc cactctagtt ctcctccaag atttctctga cctcggtcag ctccttcata
     1081 tcagttgtct ctttggtttc cttgtgaaac accttgaact tctcttggtc cttagatgaa
     1141 atgtttacag agcttctggt gatatccttc ataattttat gtcttctaaa agggtcatgg
     1201 gtgggacaca aaacaaagtg agctttgaac tgtagataat ctcttaaaag aaaatctcat
     1261 tttagaccat taaaatgttt gtgctcaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
