LOCUS       XM_006247819            3186 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus transmembrane channel-like 8 (Tmc8),
            transcript variant X2, mRNA.
ACCESSION   XM_006247819
VERSION     XM_006247819.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051345.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006247819.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006247819.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3186
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3186
                     /gene="Tmc8"
                     /note="transmembrane channel-like 8; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 8
                     ESTs, 4 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 50 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:688276"
                     /db_xref="RGD:1591150"
     CDS             502..2868
                     /gene="Tmc8"
                     /codon_start=1
                     /product="transmembrane channel-like protein 8 isoform X2"
                     /protein_id="XP_006247881.1"
                     /db_xref="GeneID:688276"
                     /db_xref="RGD:1591150"
                     /translation="MMFFQSLRFMTAGLCFAGGFSFLTSWRPFTAFDRQETKAFGPRW
                     SSAPLVTPASKDLACLSRAPTGMFRQWSVQSGPAPRRSESQASSEDLWKQEVERLCAS
                     RTPVRMLPYAMADKRFIRELREPEGVKNSCWQRWHRPRQVARQQLGEAAKRLGRGFGL
                     WEGALYEIGGLFGTGIQSYFTFLRFLLLLNLLTMLLTACFVLLPLLWLRSPEPGPALK
                     LSLQCSGSPLPQSDIPRFHNPLWNVLTGRAFNNTYLFYGAYRAGPESSSAYSIRLAYL
                     LSPLACLLLCFCVILQRMAEGLPQQTLVGQRYRTPLSAKVFSSWDFCIRVWEAATIKK
                     HEISNELKVELEEGHRLELAQQQTRAQKACRLLTYLRTNVLIVLLVIGAISAIFWATK
                     YSQDNKEESLFLVLQYLPPGVIALVNFLGPQLFTVLIQVENYPPSTEVNLTLFWCVVL
                     KLVSLGMFSFSLGQTVLCIGRNKTSCETYGYNACDYQCWENSVGEELYKLIIFNFLLT
                     VAFAFLVSLPRRLLVERFSGWFWTWLDREEFLVPKNVLDIVAAQTVTWMGLFYCPLLS
                     LLNSVFFFLTFYIKKYTLLRNSKASPRLFRASSSIFFFHLVLLLGLLLAAVPLAYVIS
                     STHSSWDCGLFTNYSAPWQVVPELVALQLPLPGQYALHYLSSHAFSFPLLFLLSLVLT
                     VCISQSRANARAIHELRKQLVWQVQEKWHLVDDLSRLLPELSPEPESPHFRASRPRSF
                     CPGFPCPGSPGPRTPWLGSSTRLSSSSLGTPSASVPASRFHFPSLTEL"
ORIGIN      
        1 caaggacagg aagtgcacgc agagggagag gaaactgtgc ggaaggcggg agtgggtgga
       61 ggggaggaga cgcagtgggc ccccaccccc gggttcctgt cacgtgaccc actccccact
      121 ccctcaccac cctgtttggt gtgttgagag ctggtcatag cagggggctc ctcggggagt
      181 ttagtccctt gcccctttgt gaactgcttg ccccgggacg ataaggacgg tgagagggga
      241 agaaggccaa ggctattgct tccttccgga cggtttggag ggggtacctt cttttctctt
      301 ggttggggat atagccacgc ctcctattct gggtccctta agaacgccag agcagacaca
      361 gcctgggcaa aacacacaga acggagccgt agtacatcca ggactggggt gttgcaggaa
      421 gctgtattgt aggagctgtc cgggttcagg acaggggtga cttcccaaaa aaaccaacca
      481 gcacatggaa aaagactggg gatgatgttt ttccaaagct taaggtttat gacagccggc
      541 ctttgctttg ccggtggctt ctctttcctc acatcctgga ggcctttcac cgcatttgac
      601 aggcaggaaa ctaaggcctt tgggccaagg tggagctcgg ctcccctcgt tactcctgcg
      661 agcaaggatc ttgcctgtct gtcccgcgcg cccactggga tgtttcgcca gtggtcggtg
      721 cagtcaggac cagccccacg aagatctgaa tcccaggcgt cctcggagga tctgtggaag
      781 caagaagtgg agcggctatg cgcctcccgg acgcctgtgc ggatgctgcc ctacgccatg
      841 gcagataagc gcttcatccg ggaactgcgg gagcccgagg gcgtgaagaa ctcctgctgg
      901 cagcggtggc atcgcccgag gcaggtggca cgacagcagc tgggggaggc agcaaaacgg
      961 ctaggccgcg gtttcgggct ctgggaggga gctctctacg agattggagg cctcttcggg
     1021 accgggatcc agtcctactt cactttcctt cgcttcctgc tgctgctcaa cctgctgacc
     1081 atgctgctga ctgcctgctt tgtgctgctg cccctgctct ggctccgctc ccctgagcca
     1141 ggccctgccc tgaaactgag tctccagtgc tccggcagcc ccctgcccca gagtgacatt
     1201 ccaaggttcc acaacccact ttggaatgtt ttaactggca gggccttcaa caacacctat
     1261 ctcttctacg gtgcctaccg agcagggcca gagagcagct cagcgtacag catccgcctg
     1321 gcctacctcc ttagcccgtt ggcctgcctg ctcctatgct tctgtgtgat actgcagagg
     1381 atggcagaag gcctcccaca gcagacactc gtgggccagc gctacaggac gcccctcagc
     1441 gccaaagtgt tctcatcctg ggacttctgc atccgggtgt gggaagccgc caccatcaag
     1501 aagcacgaga tcagcaatga actgaaggtg gagctggaag agggccaccg cttggagctg
     1561 gctcaacagc agacccgggc ccagaaggcc tgccgccttc tcacctacct gcgtaccaac
     1621 gtcctcattg tactcctagt gatcggagcc atcagcgcca tcttctgggc caccaagtac
     1681 tcacaggaca acaaggagga gtcccttttt ttggtgctcc agtacctgcc tcctggagtc
     1741 atcgccctgg tcaacttcct gggtccccaa ctgttcacag tcttgatcca ggtggagaac
     1801 taccctccca gcaccgaagt caatctcacc ctgttctggt gcgtggtact gaagctagtc
     1861 agcttgggga tgttctcctt ctccctgggt cagacggtgc tgtgcatcgg cagaaacaag
     1921 accagctgtg agacctacgg ctacaacgct tgcgactacc agtgctggga gaactcggtg
     1981 ggtgaagaat tatataaatt aatcatcttc aacttcctgc tcaccgtggc cttcgccttc
     2041 ctggtcagcc tgcctcggag gctgttagta gagcgcttct caggctggtt ctggacttgg
     2101 ctggaccggg aggagttcct ggtgcccaaa aacgtgctgg acatcgtggc tgcacagact
     2161 gtcacctgga tgggtctctt ctactgcccc ctgctgtcac tactcaacag tgtcttcttc
     2221 tttctcacct tctacatcaa gaagtacacc ctcctgagga actccaaggc atccccacgg
     2281 cttttccgag cctccagctc catcttcttc ttccatctgg tgctgctcct tggcttgctt
     2341 ttggctgcag tgcctctggc ctacgtgatc agcagcaccc actcctcctg ggactgtggc
     2401 ctcttcacaa actactcggc cccctggcag gtggtaccag agctggtggc cctccagctc
     2461 ccacttcctg gccagtatgc cctccattac ctcagctccc atgccttcag cttcccactc
     2521 ctctttctgc tcagcctcgt cctgaccgtt tgcatctccc agtcccgggc gaatgccaga
     2581 gccatccatg agctgaggaa gcaactggtg tggcaagtcc aggagaagtg gcacctggtg
     2641 gatgacctgt cgcggctgct gccggagctg agcccagagc ccgagtcccc tcactttcga
     2701 gcttcgcgtc cacgatcctt ctgcccggga ttcccatgcc caggttcacc tggtcccagg
     2761 acaccctggc tgggatcctc caccaggctg agctcttcga gcctcggaac ccccagtgcc
     2821 tcggttcccg cctccagatt tcacttcccc agcctcacag agctgtagca ccgaccccac
     2881 gtccctcggc tctacctcag cttcctccag cgcctccact cccgcccttc cacctccttt
     2941 tgcccatgct ctctgcccca cccccacccc accccgaacc acggcctaca gatggctcct
     3001 ggccctctgg caaggttctc caaagtgagc cacaccctca ggtcaccaag aagaacagga
     3061 gaatttctac ctcttttatc tcattccttc aatttttatt gagtgttgta cagtgtacaa
     3121 aacagtatga atataaactc acgggtgcaa tttataaata tatatatatt ttttgaaaca
     3181 ctggaa
//
