LOCUS       NM_001034104            2309 bp    mRNA    linear   ROD 05-AUG-2024
DEFINITION  Rattus norvegicus transmembrane channel-like 4 (Tmc4), mRNA.
ACCESSION   NM_001034104 XM_218186
VERSION     NM_001034104.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2309)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Mar 2, 2022 this sequence version replaced NM_001034104.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100657.1, SRR26643294.845.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN09345330, SAMN16676784
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               JAXUCZ010000001.1  74455135-74455249
            116-317             JAXUCZ010000001.1  74455831-74456032
            318-463             JAXUCZ010000001.1  74456937-74457082
            464-696             JAXUCZ010000001.1  74457373-74457605
            697-818             JAXUCZ010000001.1  74457748-74457869
            819-966             JAXUCZ010000001.1  74461633-74461780
            967-1134            JAXUCZ010000001.1  74462311-74462478
            1135-1298           JAXUCZ010000001.1  74462652-74462815
            1299-1425           JAXUCZ010000001.1  74463021-74463147
            1426-1523           JAXUCZ010000001.1  74463358-74463455
            1524-1707           JAXUCZ010000001.1  74465108-74465291
            1708-1838           JAXUCZ010000001.1  74465586-74465716
            1839-1994           JAXUCZ010000001.1  74465809-74465964
            1995-2073           JAXUCZ010000001.1  74466625-74466703
            2074-2309           JAXUCZ010000001.1  74466808-74467043
FEATURES             Location/Qualifiers
     source          1..2309
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..2309
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /note="transmembrane channel-like 4"
                     /db_xref="GeneID:308310"
                     /db_xref="RGD:1304811"
     exon            1..115
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..2142
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /note="transmembrane channel-like protein 4; transmembrane
                     channel-like gene family 4; transmembrane channel-like
                     protein 4-like; transmembrane channel-like 4B"
                     /codon_start=1
                     /product="voltage-gated chloride channel TMC4"
                     /protein_id="NP_001029276.2"
                     /db_xref="GeneID:308310"
                     /db_xref="RGD:1304811"
                     /translation="MEESPREAWAQFPAWSSSRKARTGPSLASVLNDLPSAATLRYRG
                     PGVLPWGTLDENDDEGRSLQAFAETAQMESQPSRELPWPMQARRAHRKSQAREQVASG
                     SESRAAYWTQQLSRTKGKMKEGFQTIQPWAWTLKKIGGQFGAGTESYFSLLRFLLFLN
                     LGASVIEVCMKLIPTWLEGAPPGPPGPNISSPCGSYIPHTQGLVTFPTQLFNLLSGEG
                     YLEWSPLFYGFYPPRSNLAITYLCSVFAIGLIYLLFILHRSVSGLKETLLAESDVLTS
                     YSHRVFSAWNFGLCGDMHVRLRQRIILYELQVDLEEAAVRRRATEQTLGQRVKVWSMR
                     ALLNLLVLALLGAAFYGIYWATEYTVTLQETPVVQQTPLLKLLVNYLPSIFISVFNFV
                     LPPAFAFIASLEGYTHSRQIVLILLRTVFLRLASLVFLLFSLWNQITCGGNMEAEECK
                     ACGYNYKEIPCWETRLGQEMYKLVLFDLLMGLLVTLLIQFPRKILCGLCPGALGRLSG
                     TLEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLINTAKFLILFWLKKITLFSIYSPASR
                     TFRASTANFFFPLVLLVGLAISAVPVLYSIFLIPPSKLCGPFQGKLSIWAQIPESIES
                     LPQTAQNFLYFLGTQAFTVPLLIVSSILMMYTVALANCYGRLISELKRQIETEVQNKV
                     FLAQRAVALSSRNGVS"
     exon            116..317
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            318..463
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            464..696
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            697..818
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            819..966
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1134
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1298
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1425
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1523
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..1707
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1708..1838
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1994
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            1995..2073
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
     exon            2074..2309
                     /gene="Tmc4"
                     /gene_synonym="Tmc4b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagacggaa acaacgggtg cagaaagtac agtccatcca caaacatgga agaaagtccc
       61 agggaagcct gggcccaatt cccggcctgg tctagttccc ggaaagccag aacaggccca
      121 tcattggcgt ctgtgctgaa tgacctcccg agtgctgcta cgcttcgata ccgtggccct
      181 ggtgtgctcc cttgggggac actggatgaa aatgatgatg aaggaagaag ccttcaggcc
      241 tttgcagaga ctgcccaaat ggaatctcag ccttcccggg aacttccctg gcctatgcaa
      301 gcaaggcggg cacacaggaa gagccaggct agagagcagg tggcttctgg ctctgaatct
      361 agggctgcct actggaccca acagctttcc agaaccaagg ggaaaatgaa agaaggcttt
      421 caaactatac agccctgggc atggacactg aagaaaattg ggggccagtt tggagcaggc
      481 actgagtcct acttctctct gctgcgcttc ctgctctttc tcaacctggg ggcatctgta
      541 attgaagtct gcatgaagct gatccccacc tggttggaag gggctcctcc aggtccacct
      601 ggccctaaca tctcctcacc ttgtggttcc tatattcccc acactcaagg cctggtcacc
      661 ttccccaccc agctcttcaa cttgctctct ggagagggtt acctagagtg gtcccctctg
      721 ttctatgggt tctacccacc ccgatcgaac ctggccatca cctatctgtg ctccgtcttt
      781 gccatcggcc tcatctactt gctgttcatc ctacaccgtt cggtgtccgg gttgaaagag
      841 acactgttgg ccgagtcaga tgttctgacc agctacagtc atcgagtgtt ctcagcttgg
      901 aattttggcc tctgcgggga catgcacgtg cggctgcgcc agcgcatcat tttgtatgaa
      961 ctgcaggtgg acctagagga agcagcagtc cggcgccgtg ctacggagca gacgctgggc
     1021 caacgagtca aggtgtggtc gatgagggcg ctgctcaact tgctagtcct cgcgctcctg
     1081 ggggctgcct tctatggcat ctactgggcc acagagtaca ccgtgacact gcaggagaca
     1141 ccagttgtcc aacagacccc actactcaag cttctggtga attatcttcc atctatcttc
     1201 atttccgtgt tcaactttgt gctgcctcct gcgttcgcgt tcattgcctc actagagggc
     1261 tacactcaca gccgtcagat cgtcttgatc ctgcttagga ctgtgttttt gcgtctggcc
     1321 tccctggtgt ttcttctgtt ctctctgtgg aatcagatca cgtgtggagg aaacatggag
     1381 gcagaagaat gcaaggcttg tggctacaat tacaaagaaa ttccgtgctg ggagactcga
     1441 ctgggccagg agatgtacaa acttgtgctc tttgatctgc tgatgggcct gttggtcacg
     1501 ctgttgatcc agtttcctag gaagatactc tgtggcctct gtcctggggc attgggtcgt
     1561 ctgtcgggaa ctctggagtt ccaggtgccc gatgaagtgc tgggactcat ctatgctcag
     1621 accgtggtct gggtaggaag ctttttctgc cctttactac ctttgatcaa caccgccaag
     1681 ttcctcatac ttttttggct gaagaagatc acactcttct ccatctactc accggcttcc
     1741 cgaaccttcc gagcatccac agcaaatttc tttttccccc tggtactcct tgtgggtctg
     1801 gcaatctctg ctgtccctgt gctttacagt atcttcctga tcccaccttc taagctgtgt
     1861 ggcccattcc aagggaagtt gtccatttgg gcccagatcc ctgagtccat tgagagcctc
     1921 cctcagactg cccagaattt tctctacttt ctgggaaccc aggcttttac tgtacccctt
     1981 ctgatcgtct ctagcatcct gatgatgtat acagtagccc tggctaactg ttatggacgc
     2041 ctcatctctg agctcaaacg ccagatagag acggaagtac aaaataaagt cttcctagcc
     2101 cagcgagctg tagctctgag ctcaaggaat ggagtttcct gattagtctg gctggacctt
     2161 cagcccctca cacccatcat aaacttcatt gacttcatat accaagcagt ggggccctct
     2221 catctctgga atcaaacccc acgccttctg ccaccgaatg ccacactctc aattgaacca
     2281 tgttaataaa caatagccaa gtccattaa
//
