LOCUS       NM_001007713            2099 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus transmembrane BAX inhibitor motif containing 1
            (Tmbim1), mRNA.
ACCESSION   NM_001007713 XM_237311
VERSION     NM_001007713.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2099)
  AUTHORS   Shukla S, Fujita K, Xiao Q, Liao Z, Garfield S and Srinivasula SM.
  TITLE     A shear stress responsive gene product PP1201 protects against
            Fas-mediated apoptosis by reducing Fas expression on the cell
            surface
  JOURNAL   Apoptosis 16 (2), 162-173 (2011)
   PUBMED   21107705
REFERENCE   2  (bases 1 to 2099)
  AUTHORS   Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta
            R, Wang NS and Knepper MA.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   3  (bases 1 to 2099)
  AUTHORS   Schroder B, Wrocklage C, Pan C, Jager R, Kosters B, Schafer H,
            Elsasser HP, Mann M and Hasilik A.
  TITLE     Integral and associated lysosomal membrane proteins
  JOURNAL   Traffic 8 (12), 1676-1686 (2007)
   PUBMED   17897319
REFERENCE   4  (bases 1 to 2099)
  AUTHORS   Zhao H, Ito A, Sakai N, Matsuzawa Y, Yamashita S and Nojima H.
  TITLE     RECS1 is a negative regulator of matrix metalloproteinase-9
            production and aged RECS1 knockout mice are prone to aortic
            dilation
  JOURNAL   Circ J 70 (5), 615-624 (2006)
   PUBMED   16636500
REFERENCE   5  (bases 1 to 2099)
  AUTHORS   Zhao H, Ito A, Kimura SH, Yabuta N, Sakai N, Ikawa M, Okabe M,
            Matsuzawa Y, Yamashita S and Nojima H.
  TITLE     RECS1 deficiency in mice induces susceptibility to cystic medial
            degeneration
  JOURNAL   Genes Genet Syst 81 (1), 41-50 (2006)
   PUBMED   16607040
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079087.1.
            
            On Nov 29, 2004 this sequence version replaced XM_237311.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079087.1, SRR8487226.205060.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434, SAMN16676789
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2099
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q33"
     gene            1..2099
                     /gene="Tmbim1"
                     /note="transmembrane BAX inhibitor motif containing 1"
                     /db_xref="GeneID:316516"
                     /db_xref="RGD:1359409"
     exon            1..16
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            17..258
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..986
                     /gene="Tmbim1"
                     /note="transmembrane BAX inhibitor motif-containing
                     protein 1"
                     /codon_start=1
                     /product="protein lifeguard 3"
                     /protein_id="NP_001007714.1"
                     /db_xref="GeneID:316516"
                     /db_xref="RGD:1359409"
                     /translation="MSNPTAPPPYEDHNPLYPGRPPPGGYGQPSVLPGGYPAYPAYPQ
                     PGYGHPAGYPQPIPPVHPMPMNYGHDYSEEERAGSDSFGPGEWDDRKVRHTFIQKVYC
                     IISVQLLITVAIIAVFTFVEPVSEYVRSNVAVYYVSYAVFIVTYLILVCCQGPRRRFP
                     WNIILLTIFTLALGFMTGAISSMYETKAVIIAMIITAVVSISVTIFCFQTKVDFTSCT
                     GLICVLGIVLAVTGAVTSVVLFFEYIYWLHMVYAGLGAICFTLFLAYDTQLVLGNRKH
                     TISPEDYITGALQIYTDIVYIFTFVLQLVGNRD"
     exon            259..353
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            354..418
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            419..472
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            473..523
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            524..563
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            564..601
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            602..689
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            690..785
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            786..839
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
     exon            840..2068
                     /gene="Tmbim1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccggaaca gcgcaggtcc cagaagctag ggtttcccct cagcccttga gtggccatgt
       61 ccaatcccac tgccccacct ccctatgagg accacaaccc cctgtaccct ggccgtccac
      121 ctcctggggg ctacggacag ccgtctgtcc tgcctggtgg ttaccctgcc taccccgcct
      181 accctcaacc tggttacggg caccctgctg gctacccaca gccgattcct cctgtccatc
      241 caatgcccat gaactacggc catgactata gtgaggagga gagagcagga agtgacagct
      301 ttggtcctgg agaatgggat gaccggaaag tccgacatac cttcatccaa aaggtgtact
      361 gcatcatttc tgtccagctg ctcatcactg tggccatcat tgctgtcttc acctttgtgg
      421 aaccagtcag tgaatatgtg aggagcaatg tggcggtgta ctacgtgtcc tatgctgtct
      481 tcattgtcac ctacctgatc cttgtctgct gccagggacc cagacgccga ttcccatgga
      541 acattatcct gctaaccatc tttactttgg ctttgggctt tatgacaggc gctatttcca
      601 gtatgtatga aaccaaagct gtcatcattg ctatgatcat cactgccgtg gtatccattt
      661 ctgtcaccat cttctgcttt cagactaagg tggacttcac ctcatgtaca ggcctcatct
      721 gtgtgctggg aatagtgttg gcagtaaccg gtgctgtcac aagcgtagtg ctgttttttg
      781 aatatattta ctggctccac atggtctacg caggtctggg ggccatctgt ttcaccctgt
      841 tcctggctta tgacacgcag ctggtcctgg ggaaccggaa gcataccatc agcccagagg
      901 actacatcac aggcgccctg cagatctaca cagatatagt ctacatcttc acctttgtgc
      961 tccagcttgt aggaaatcga gactgagaca gagagggaga gagatgtccc tttcactggc
     1021 ctgggactca cattgtctcc cctcaagtaa tctgctcagt ttcctctccg tcctggggat
     1081 gggagggtct ctggctgtgt tctgtgagag ccatgagtgc tggggttact ggcacctctt
     1141 gcccttggtg ggcttgataa gaactagatt gaaggtgttt ctccttccct tcacccacaa
     1201 tgagtatgca ccaaactttt catgtgtgtg tgtgtgtgga gggggagtag ggagccggtg
     1261 aacacaggag ctctgaggtg aagagggtcc tctcccacct cggccacagg gttctaggct
     1321 aggagctgga gctgtttccc tcctggatcc aataaagcca gatgcttcac ctctagctcc
     1381 agtgctcata ggccacttat gctgtctgaa ctctttaggc ttggcatctc ttagctttag
     1441 aagctagaag agatctgtgc cctggggtct ctctgttcca accccatctt ccagtaacac
     1501 gtatccatta tttatctggg ctaggggaaa agacagtgag caaagacagt atggggggag
     1561 agtagcacag aatggtgtcc ccctgactgg cacccatctt ggctaccatc caggtccaaa
     1621 gtgcttgagg ccttctgagg cttttaaaat ctgacctaga gggacctcct actttgcttt
     1681 gacacacaga ggtggaggtc agcaagtaag gtggattgtg ggatgagtgg ggacagggaa
     1741 agtgccttgg gtgcccctct ggtttgagaa actgaaacgt actctggtat gtagcaacct
     1801 tcctccccaa cacaagttca atctgttctg tgttcctact gggagatttt agactaaaac
     1861 ccctcttcaa gccagctgct gtttctctgt aatccaagtg cctccaactg gcaccatggt
     1921 ggggatagaa gccagtttat caggtggagt agaaacctta ttagcccaag gacatagttc
     1981 agagctattc tgtccagtac ttgattctga atctaataca aagggacgca actagaaata
     2041 taataaagtt ctatgtttgg caagaagaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
