LOCUS       NM_001025649            2273 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane 9 superfamily member 4 (Tm9sf4),
            mRNA.
ACCESSION   NM_001025649 XM_215889
VERSION     NM_001025649.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2273)
  AUTHORS   Lozupone,F., Borghi,M., Marzoli,F., Azzarito,T., Matarrese,P.,
            Iessi,E., Venturi,G., Meschini,S., Canitano,A., Bona,R., Cara,A.
            and Fais,S.
  TITLE     TM9SF4 is a novel V-ATPase-interacting protein that modulates tumor
            pH alterations associated with drug resistance and invasiveness of
            colon cancer cells
  JOURNAL   Oncogene 34 (40), 5163-5174 (2015)
   PUBMED   25659576
REFERENCE   2  (bases 1 to 2273)
  AUTHORS   Perrin,J., Le Coadic,M., Vernay,A., Dias,M., Gopaldass,N.,
            Ouertatani-Sakouhi,H. and Cosson,P.
  TITLE     TM9 family proteins control surface targeting of glycine-rich
            transmembrane domains
  JOURNAL   J Cell Sci 128 (13), 2269-2277 (2015)
   PUBMED   25999474
REFERENCE   3  (bases 1 to 2273)
  AUTHORS   Paolillo,R., Spinello,I., Quaranta,M.T., Pasquini,L., Pelosi,E., Lo
            Coco,F., Testa,U. and Labbaye,C.
  TITLE     Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved
            in Cell Adhesion of Leukemic Cells
  JOURNAL   PLoS One 10 (5), e0126968 (2015)
   PUBMED   25961573
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2273)
  AUTHORS   Lozupone,F., Perdicchio,M., Brambilla,D., Borghi,M., Meschini,S.,
            Barca,S., Marino,M.L., Logozzi,M., Federici,C., Iessi,E., de
            Milito,A. and Fais,S.
  TITLE     The human homologue of Dictyostelium discoideum phg1A is expressed
            by human metastatic melanoma cells
  JOURNAL   EMBO Rep 10 (12), 1348-1354 (2009)
   PUBMED   19893578
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099133.1.
            
            On Jul 22, 2005 this sequence version replaced XM_215889.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099133.1, SRR8487226.33707.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2273
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..2273
                     /gene="Tm9sf4"
                     /note="transmembrane 9 superfamily member 4"
                     /db_xref="GeneID:296279"
                     /db_xref="RGD:1307768"
     exon            1..226
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     CDS             212..2143
                     /gene="Tm9sf4"
                     /note="transmembrane 9 superfamily protein member 4"
                     /codon_start=1
                     /product="transmembrane 9 superfamily member 4 precursor"
                     /protein_id="NP_001020820.1"
                     /db_xref="GeneID:296279"
                     /db_xref="RGD:1307768"
                     /translation="MAAAMIWWPRFLLLLCLTCKGSTFYVPGVAPINFHQNDPVEIKA
                     VKLTSSRTQLPYEYYSLPFCQPNKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEV
                     LCGQSNKPVILTVEQSRLVAERITEEYYVHLIADNLPVATRLELYSSNRDSDDKKKEK
                     DVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDTEEDQEHTYRVVRFEVIPQSIRLE
                     DLKIDEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSD
                     VQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGD
                     VFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGV
                     FGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTM
                     VALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAG
                     ILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDY
                     RWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTI
                     GFYAAYMFVRKIYAAVKID"
     exon            227..340
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            341..440
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            441..609
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            610..742
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            743..866
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            867..985
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            986..1097
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1168
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1301
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1383
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1459
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1460..1543
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1719
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1720..1783
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1784..1903
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1904..1993
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
     exon            1994..2250
                     /gene="Tm9sf4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctccaata gttacaccgt atgttctctt cacctagtca gagacctcac tgccagacca
       61 gtttgtcaag gagaaattaa gcttctttta cctcctcact actgcgacta cagaagaatt
      121 tgaaccaagg agtcccctta gtggggatac actcggtacc cacagaagca ccacttccgc
      181 tgacgtcatc acgctgacac gtggatccaa gatggcggcg gcgatgattt ggtggccgag
      241 gttcctacta cttctctgtc taacgtgtaa aggaagcacc ttctatgtcc ctggagtcgc
      301 gccaatcaac ttccaccaaa acgacccagt agagatcaag gctgtgaagc ttaccagctc
      361 tcgaacccag cttccttatg agtactattc attgcccttc tgccagccca acaagataac
      421 ctacaaggca gagaatctag gagaggtgct gagaggggac cggattgtca acaccccttt
      481 ccaagttctc atgaacagtg agaagaagtg tgaagttctg tgcggccagt ccaacaagcc
      541 agtaatcttg acagtggaac agagccggct ggtggccgag cgaatcacag aagagtacta
      601 tgttcacctc attgctgaca acctgcctgt ggccacccgg ctggagctct actccagcaa
      661 ccgtgacagt gatgacaaga agaaagaaaa agacgtgcag tttgaacatg gctacagact
      721 tggcttcacg gatgtcaaca agatctacct gcacaatcac ctctcgttca tcctttatta
      781 ccatcgggag gacacggaag aggatcagga gcacacgtac cgagtcgtcc gcttcgaggt
      841 gattccccag agcatcaggc tggaggacct caaaatagac gagaagagct catgtaccct
      901 acccgagggt gccaactcct taccccaaga aattgacccc actaaggaga atcagctgta
      961 cttcacctac tctgtgcact gggaggaaag tgacatcaag tgggcctctc gatgggacac
     1021 ttacctaacc atgagtgatg tgcagatcca ctggttttcc atcattaact ctgtcgtggt
     1081 ggtcttcttc ctgtcaggca tcctcagcat gattatcatc cggacgctgc ggaaggacat
     1141 cgccaactac aacaaggagg atgacattga agacactatg gaggagtctg ggtggaagct
     1201 tgtgcatggt gacgtcttca ggccgcccca gtatcccatg atcctcagct ctctgctagg
     1261 ctcaggcatt cagctcttct gcatgatcct gattgtcatc tttgtggcca tgcttgggat
     1321 gctgtcgccc tccagccggg gagcgctcat gaccacagcc tgcttcctct tcatgttcat
     1381 gggggtattt ggtggatttt ctgctggccg cctttacaga actctaaagg gccatcggtg
     1441 gaagaaagga gccttctgta cagcgacact gtatcctggc gtggtttttg gcatctgctt
     1501 tgtgttgaat tgcttcatct ggggaaagca ctcatcagga gcggtaccct ttcccaccat
     1561 ggtggcgttg ctgtgtatgt ggttcgggat ctccctgccc cttgtctact taggctacta
     1621 tttcggcttc cgcaagcagc catatgacaa ccctgtgcgc acaaaccaga ttccccggca
     1681 gatccctgag caacggtggt acatgaaccg atttgtgggc atcctcatgg ctgggatcct
     1741 gccctttggt gccatgttta ttgagctgtt cttcatcttc agtgcaatct gggagaacca
     1801 gttctattac ctcttcggtt tcctattcct tgttttcatc atcctggtgg tatcctgttc
     1861 acagatcagc atcgtcatgg tgtacttcca actgtgtgca gaggattacc gctggtggtg
     1921 gaggaatttc cttgtctcag ggggatctgc attctacgtc ctggtttatg ccatctttta
     1981 ttttgttaac aagctggaca tcgtggagtt catcccttct ctcctctact ttggctacac
     2041 caccctcatg gtcctgtcct tctggctgct cacagggacc atcggcttct atgcagccta
     2101 catgtttgtc cgcaagatct atgctgctgt gaagatagac tgagtgggtg aaccaacact
     2161 aggcccactg gatcctcgga caggaagcca ccctgcgtgg ggaactgcag gcacacaaaa
     2221 taaaataact cctgctcatt tggaatgtaa aaaaaaaaaa aaaaaaaaaa aaa
//
