LOCUS       NM_001011970            2074 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane 7 superfamily member 3 (Tm7sf3),
            mRNA.
ACCESSION   NM_001011970 XM_216312
VERSION     NM_001011970.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2074)
  AUTHORS   Isaac,R., Goldstein,I., Furth,N., Zilber,N., Streim,S.,
            Boura-Halfon,S., Elhanany,E., Rotter,V., Oren,M. and Zick,Y.
  TITLE     TM7SF3, a novel p53-regulated homeostatic factor, attenuates
            cellular stress and the subsequent induction of the unfolded
            protein response
  JOURNAL   Cell Death Differ 24 (1), 132-143 (2017)
   PUBMED   27740623
REFERENCE   2  (bases 1 to 2074)
  AUTHORS   Beck,A., Isaac,R., Lavelin,I., Hart,Y., Volberg,T.,
            Shatz-Azoulay,H., Geiger,B. and Zick,Y.
  TITLE     An siRNA screen identifies transmembrane 7 superfamily member 3
            (TM7SF3), a seven transmembrane orphan receptor, as an inhibitor of
            cytokine-induced death of pancreatic beta cells
  JOURNAL   Diabetologia 54 (11), 2845-2855 (2011)
   PUBMED   21853325
REFERENCE   3  (bases 1 to 2074)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   4  (bases 1 to 2074)
  AUTHORS   Akashi,H., Han,H.J., Iizaka,M., Nakajima,Y., Furukawa,Y.,
            Sugano,S., Imai,K. and Nakamura,Y.
  TITLE     Isolation and characterization of a novel gene encoding a putative
            seven-span transmembrane protein, TM7SF3
  JOURNAL   Cytogenet Cell Genet 88 (3-4), 305-309 (2000)
   PUBMED   10828615
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC090030.1.
            
            On Feb 11, 2005 this sequence version replaced XM_216312.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC090030.1, SRR8487226.198147.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2074
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q44"
     gene            1..2074
                     /gene="Tm7sf3"
                     /note="transmembrane 7 superfamily member 3"
                     /db_xref="GeneID:297725"
                     /db_xref="RGD:1306752"
     exon            1..172
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..1794
                     /gene="Tm7sf3"
                     /codon_start=1
                     /product="transmembrane 7 superfamily member 3 precursor"
                     /protein_id="NP_001011970.1"
                     /db_xref="GeneID:297725"
                     /db_xref="RGD:1306752"
                     /translation="MWRLRLLVLAVLAAGSAEAQANSSDGFLEFSVGKFTYFVLSRRF
                     PQEAVLRHISSNVTFLLFQIHSQYQNTTVSYTKTLLPSTSGTGNDRGLVFILRPEQTV
                     CTWYLETEDTKPVQSVAVTLSYSERDPIPGGCNLEFDLDIDPNIYLDYNFFETTIKFA
                     PANIGYARAAEPPPCDVSTGQESRWRLRYHVYQYFLPEGDLTEASLLQHLQRMAQVVQ
                     VMASAVKVVTLTADDKTVVSFSSLPGQGVIYNVIVWDPSLNTSAAYVPVHTYACSFDS
                     VDGNCVPPGRVSTKVFSTLFALLGLFTCFFGHRFWKTELFFVGFIFLGFFFYILITRL
                     TALKYEVRLVLTAVAGSIGGLLLVASWWRFGILTLCMLCVGLVLGFLVSSGTFFTPLG
                     NLNVFHDDGVFWVTFSCIALLVPVIFLGCLRILNILACGIVGSYSVVLAINSYMFTSL
                     SYITLNVLRRALNADFRGAFIRVPFQTNDYIILAVWGMLAVTGITLQIRRERGRPPFP
                     PHPYKLWKQERERRVTNILDPSHHIPPLRERLYGWVARIKELFQKEQPAGERTPLLL"
     exon            173..327
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            328..478
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            479..599
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            600..771
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            772..949
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1036
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1117
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1118..1270
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1368
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1531
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
     exon            1532..2050
                     /gene="Tm7sf3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcaggtgca cgcgcggggc cagcgggtga gagcgatgcg cgcgggctct ccggggtaga
       61 gccccgaccc ggcctgcgcg cccccggccc gcagtgatgt ggcggctgcg cctgctggtc
      121 ctggcggtgc tggcggcggg cagcgcggag gcccaggcga actccagcga cggtttcctt
      181 gaattttctg tgggaaaatt tacgtacttt gtgctcagca ggcgctttcc acaggaggcc
      241 gttctgcgcc acatttcaag caatgtgacc tttcttcttt tccaaataca ctcacagtat
      301 cagaacacca cagtttcata tactaagact ctcctcccca gcacctcagg aacaggcaac
      361 gacagaggac tggttttcat tcttagacca gagcagactg tgtgcacttg gtacttggag
      421 acagaagaca ctaagcccgt tcagagtgtg gccgttacac tctcctactc agaaagagat
      481 cccattcctg gaggctgtaa tttggaattt gatttagata tagatcccaa catctacttg
      541 gactataatt tttttgaaac aactatcaag tttgctccag caaacatagg ctatgcaaga
      601 gctgcagagc ccccaccgtg tgacgtgagc acaggccagg agtccaggtg gaggctgcgc
      661 taccatgtgt atcagtactt tctgcccgag ggcgacctca ccgaggcctc tctgctccag
      721 catcttcaga ggatggccca ggtggtccag gtgatggcca gtgctgtcaa ggtggttact
      781 ctaacagctg acgataagac agtcgtgtcc ttctcttccc ttccgggaca aggggtcatc
      841 tataatgtca tcgtttggga tccctccctc aatacctctg ctgcttatgt gcccgtgcac
      901 acgtatgcct gcagtttcga ttcagtggat ggtaactgcg ttcctcctgg aagagtatct
      961 acgaaagtgt tctccactct gtttgccctg ctcgggctct tcacttgttt ctttggacac
     1021 agattctgga aaacagaatt attcttcgtg ggtttcatct tcctggggtt cttcttttac
     1081 atcctgatca ccagactgac ggccctgaag tacgaagttc gcctggtcct caccgccgta
     1141 gctggcagca ttggtggact cctcctggtg gcctcgtggt ggcgattcgg gatcctcaca
     1201 ctgtgcatgc tgtgtgtggg gctcgtgctg ggcttcctcg tctcttctgg gactttcttc
     1261 actcccctgg gaaacctaaa tgtctttcat gatgatggag tgttctgggt gacgttctcc
     1321 tgcatagctc tgcttgttcc agtcatcttc cttggctgcc tgaggatact gaacatcctg
     1381 gcttgtggaa tagtgggctc ctactccgtg gtgttggcca ttaacagtta catgttcacg
     1441 agcctctcct acatcacgct gaacgtcctc aggagagctc tcaacgcgga ttttcgaggg
     1501 gctttcatca gagtgccttt ccagaccaac gactacatca tcctggccgt gtggggaatg
     1561 ctggctgtca ctggaattac acttcagatt cgaagagaaa ggggtcggcc gcccttccca
     1621 ccccatccct acaagctatg gaagcaagag agagaacgca gagtgaccaa cattctggac
     1681 cccagccatc acatccctcc cctgagagag aggctttatg gctgggttgc tcggatcaaa
     1741 gagctcttcc agaaggaaca accggctgga gagcggacac ccctgcttct gtagagggcc
     1801 atgtgcttgc cctggagttc tcttctagac tgcccagctg tcccaggtcc agtggggggg
     1861 gggtcagctg gggtcagtga tcaggtgacc ccttgttggc atacagcagt ggtaaggtga
     1921 gaaaagtcac caaaaagttg gttgtagatg tttttcctca ttttccacaa tcttgagacg
     1981 ataccttttg gtttataaat agatgatgtc ttttataaaa tacactaaaa aataaaaatt
     2041 tctccttaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
