LOCUS       NM_001127654            1412 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus transmembrane 6 superfamily member 2 (Tm6sf2),
            mRNA.
ACCESSION   NM_001127654 XM_001068287
VERSION     NM_001127654.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1412)
  AUTHORS   Mahdessian,H., Taxiarchis,A., Popov,S., Silveira,A.,
            Franco-Cereceda,A., Hamsten,A., Eriksson,P. and van't Hooft,F.
  TITLE     TM6SF2 is a regulator of liver fat metabolism influencing
            triglyceride secretion and hepatic lipid droplet content
  JOURNAL   Proc Natl Acad Sci U S A 111 (24), 8913-8918 (2014)
   PUBMED   24927523
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158807.1.
            
            On May 25, 2008 this sequence version replaced XM_001068287.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158807.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1412
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..1412
                     /gene="Tm6sf2"
                     /note="transmembrane 6 superfamily member 2"
                     /db_xref="GeneID:689029"
                     /db_xref="RGD:1597457"
     exon            1..108
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..1150
                     /gene="Tm6sf2"
                     /codon_start=1
                     /product="transmembrane 6 superfamily member 2"
                     /protein_id="NP_001121126.1"
                     /db_xref="GeneID:689029"
                     /db_xref="RGD:1597457"
                     /translation="MDIPPLAGRTVAMSLGALPVSYVLNQVSAFSQPLCVVLTSALVL
                     GLLFMAVYSLSHGEITYDPLYAVFVVFSFTSVVDLVIALQEDGYLMGLMDFYAKEGEP
                     YLRTAHGIFICYWDGTVHYLLYLTMAGAIRKRKRYRNLGLYWLGSFAMSLLVFLPGNI
                     LGKYSSEIRPTFFLAILYMLVPCWAGMRIFNQSPAPSSCTCDVVQEEQKKSLLQRPAD
                     LTLIVYLILAAFFTVFRGLVVLDCPADACFIYIYQYEPYLRDPVAYPKLQMLMYLFYA
                     LPFYCLAAYALTFPGCSWLPDWALVFAGAIGQAQFSHMGASMHLRTPFTYRVPEDTWA
                     TFLLSNLLFALGPHLLALRCLWRPAFFLRAAPPSSPQDQGKKQQ"
     exon            109..212
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            213..310
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            311..414
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            415..497
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            498..622
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            623..724
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            725..817
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            818..937
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1387
                     /gene="Tm6sf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggtgccgct gccatggaca tcccgccgct agccggcagg actgtggcga tgtcactcgg
       61 tgctctgcca gtgtcctacg tactcaacca agtttcggcg ttctcacagc ccctgtgtgt
      121 ggtgctgacg agtgctctgg tactgggtct gcttttcatg gctgtctaca gcctatctca
      181 tggggagatc acctatgacc ctctctatgc tgtctttgtg gtcttctcct tcacctcggt
      241 ggtggacctg gtcattgcac tccaagaaga tggctacttg atgggcctta tggatttcta
      301 cgccaaggag ggcgagccct acctacgcac agcgcacggc atcttcatct gctactggga
      361 tggtactgtg cactacctgc tctatctaac aatggctggt gccatccgca aaaggaaaag
      421 gtaccggaac cttgggctct actggctggg gtccttcgct atgagcctcc tggtgtttct
      481 cccaggaaac atccttggta aatacagttc agagatcaga cctaccttct tccttgccat
      541 cctgtacatg ctggttccat gctgggccgg tatgaggatc ttcaaccagt cgcctgcacc
      601 aagctcctgc acctgtgatg tggtacagga agaacagaag aaaagcctcc tacagcgccc
      661 ggctgacctg acactcatag tttacctcat ccttgctgca tttttcactg tcttccgggg
      721 cctggtagta cttgactgcc ccgcagatgc ctgcttcatc tatatttacc aatatgaacc
      781 ataccttcgg gaccctgtgg cctacccaaa gttgcagatg ctgatgtatt tgttctatgc
      841 tctaccattc tactgcctgg ctgcctatgc tctcaccttc cctggctgct cctggctgcc
      901 ggattgggcc ttggtatttg ctggagccat tggccaggcg cagttctcac acatgggtgc
      961 ctccatgcac ctacgcacac ccttcaccta ccgcgtgcca gaggacacct gggccacctt
     1021 tcttctgagc aacctgctgt ttgcactggg tccccacctg ctggctctcc gctgcctgtg
     1081 gcggccggcc ttctttttgc gtgcagcacc gccatcttcg ccccaggacc aaggcaagaa
     1141 gcagcagtga gcatgtgcac ctctctgcta agacttctac ctatgcaacc gtcgttgccc
     1201 tctaggtgtg ggttggccat ggaatgatgg acatgcggag aaattgcgat ccaggccaga
     1261 aaggagcatc agtgttcttg ctactacgtt actgtgcctc aaaggtcaca aggactttag
     1321 tgccctctcc tgaaatctag ccatcgcctc ccccatcctt taataaaaac cgttctctta
     1381 tctagaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
