LOCUS       NM_001106434            1950 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane 4 L six family member 1 (Tm4sf1),
            mRNA.
ACCESSION   NM_001106434 XM_001060042 XM_215576
VERSION     NM_001106434.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1950)
  AUTHORS   Hong,J., Wong,B., Huynh,C., Tang,B., Ruffenach,G., Li,M., Umar,S.,
            Yang,X. and Eghbali,M.
  TITLE     Tm4sf1-marked Endothelial Subpopulation Is Dysregulated in
            Pulmonary Arterial Hypertension
  JOURNAL   Am J Respir Cell Mol Biol 68 (4), 381-394 (2023)
   PUBMED   36252184
  REMARK    GeneRIF: Tm4sf1-marked Endothelial Subpopulation Is Dysregulated in
            Pulmonary Arterial Hypertension.
REFERENCE   2  (bases 1 to 1950)
  AUTHORS   Cui,W., Dai,X., Marcho,C., Han,Z., Zhang,K., Tremblay,K.D. and
            Mager,J.
  TITLE     Towards Functional Annotation of the Preimplantation Transcriptome:
            An RNAi Screen in Mammalian Embryos
  JOURNAL   Sci Rep 6, 37396 (2016)
   PUBMED   27869233
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1950)
  AUTHORS   Marken,J.S., Bajorath,J., Edwards,C.P., Farr,A.G., Schieven,G.L.,
            Hellstrom,I., Hellstrom,K.E. and Aruffo,A.
  TITLE     Membrane topology of the L6 antigen and identification of the
            protein epitope recognized by the L6 monoclonal antibody
  JOURNAL   J Biol Chem 269 (10), 7397-7401 (1994)
   PUBMED   7510285
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474003.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215576.4, XM_001060042.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ220762.1, CK601973.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16093042, SAMN16093043
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1950
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q26"
     gene            1..1950
                     /gene="Tm4sf1"
                     /note="transmembrane 4 L six family member 1"
                     /db_xref="GeneID:295061"
                     /db_xref="RGD:1309652"
     exon            1..516
                     /gene="Tm4sf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             340..948
                     /gene="Tm4sf1"
                     /note="transmembrane 4 superfamily member 1"
                     /codon_start=1
                     /product="transmembrane 4 L6 family member 1"
                     /protein_id="NP_001099904.1"
                     /db_xref="GeneID:295061"
                     /db_xref="RGD:1309652"
                     /translation="MCYVKCARYIGFSLVWAAVFCIVANVLLYFPNGETKYATEGHLS
                     RFVWYFAGIVGGGLLMLLPAFLFIRLEEEDCCGCCGYENYGKRCSMLSSVLAALIGIT
                     GSGYCVIVASLGLAEGPKCSDANGVWNYTFASTEGQYLLDSSMWSKCYEPKHIVEWHV
                     TLFSILLAFAAIEFILCLIQVINGVLGGTCGYCCSRQQQYNC"
     exon            517..606
                     /gene="Tm4sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            607..752
                     /gene="Tm4sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            753..933
                     /gene="Tm4sf1"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1950
                     /gene="Tm4sf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgagcaagc ggcgtagtgg attagtcatt ttctctcctg caggtgactg aggatgtttc
       61 tcacatccta ctacagggtt tcgttgtccc aaggatttca tttgaagggt ggggcactcc
      121 ttcacttcct tccacccgga ccggagactg aagtctggac caatgaaagc ggagaacctc
      181 atttactggc actaagaact ggcactattt aagtggtagc aggaatgggt tgtgagcgtc
      241 ggctttctct acaaaggggc actccatcat cccatctgtg gcaccgctga gctgaagaga
      301 gggaacagag caaagcagtg caggactcct gctgccacta tgtgctatgt aaagtgtgca
      361 agatacatcg gattctctct ggtgtgggct gctgtcttct gcatcgtagc taatgttttg
      421 ctctactttc ctaatgggga aacaaaatac gctaccgagg gccacctcag ccgcttcgtg
      481 tggtactttg ctggcattgt aggaggaggc ttgctgatgc tcctgccggc gtttttgttc
      541 attcggctgg aggaagagga ctgttgtggc tgctgcggct atgaaaacta cggcaagaga
      601 tgctcgatgc tctcttctgt actggctgct ctgattggaa tcacgggatc tggctactgt
      661 gttattgtgg catcgctggg tttggcagaa ggaccaaagt gtagcgatgc caacggagtg
      721 tggaactaca cctttgccag cactgaggga cagtaccttc tggattcctc tatgtggtcc
      781 aagtgctatg agcccaagca tattgtggag tggcatgtga ctctattttc tatcctcttg
      841 gcttttgctg ccattgaatt catcttgtgt ctcattcaag taataaacgg agtgcttggg
      901 ggcacgtgtg gctattgctg ctctcgccaa cagcaatata actgctaaaa aagaacagaa
      961 gacagattgg catgcttcct gtatttcatt gtaatttgta tattttacct gtgttgtgag
     1021 actttgcacc attgtgtggt atcccaccct ttctgctttc ataaggaaat gtgctgacat
     1081 catggcatga tgtcagtgct tacattcata aaacaaactt tggtttgaag aatgtgacag
     1141 caaactgcac tctctcagaa gggattttac agacttaatg actgttctca gcatagctga
     1201 gataaactct tcaatgtttg agataaaaaa tcatatctaa ctattgtgca tatgtgcatt
     1261 tgtttttttt taaataaaag acctctggct tccttttaaa gatcaagaag gataaagaag
     1321 gatatatttt attgtttata tgctgttacc cttttgtatg tgaacacgtc tctaagagac
     1381 ccaaagtgag agaaaagcac ttgcctgatt aagaaatctt attgagaaag cgctaacacg
     1441 agtatggcag agaaactatg taaagctgtc agtggttgtg aacactacta gatgctgaag
     1501 ctttctagca tgtagaaagc tttttgccct tcaaagtcaa aggctgtttc tttaaagaag
     1561 aaggtcagga tagttagaca agaagggaaa tgagaaatgg aaaaaagtgg ttgatcatca
     1621 tggtgggaaa atgggagagg taaagcaggg tcaggaagct cacaagggaa tgcttcccag
     1681 acttggttgt tgacaataaa gttaaggatt catcaccatt cagctgtggt tttagtttta
     1741 tgtctgaagt gacaccctct ctcattaggc aatttatcac tgtcacgtag agaggacttc
     1801 ttcctaacgt ttaggaagat ctattacctt ttttggatga caaaagatat tttcagagta
     1861 cagtcttttg ggtatggaga tctggtttct aacttaatag aatttgactt gaaaggttac
     1921 acacagtgaa tacacccagt aggacaagtc
//
