LOCUS       NM_001108670            1000 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus TM2 domain containing 1 (Tm2d1), mRNA.
ACCESSION   NM_001108670 XM_001059680 XM_342866
VERSION     NM_001108670.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Kajkowski,E.M., Lo,C.F., Ning,X., Walker,S., Sofia,H.J., Wang,W.,
            Edris,W., Chanda,P., Wagner,E., Vile,S., Ryan,K.,
            McHendry-Rinde,B., Smith,S.C., Wood,A., Rhodes,K.J., Kennedy,J.D.,
            Bard,J., Jacobsen,J.S. and Ozenberger,B.A.
  TITLE     beta -Amyloid peptide-induced apoptosis regulated by a novel
            protein containing a g protein activation module
  JOURNAL   J Biol Chem 276 (22), 18748-18756 (2001)
   PUBMED   11278849
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Aug 6, 2021 this sequence version replaced NM_001108670.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF110699.1, CB607031.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760393,
                                           SAMEA5760434 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-205               JAXUCZ010000005.1  118166272-118166476 c
            206-279             JAXUCZ010000005.1  118164054-118164127 c
            280-388             JAXUCZ010000005.1  118156600-118156708 c
            389-480             JAXUCZ010000005.1  118151132-118151223 c
            481-554             JAXUCZ010000005.1  118147680-118147753 c
            555-683             JAXUCZ010000005.1  118138938-118139066 c
            684-1000            JAXUCZ010000005.1  118136299-118136615 c
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q33"
     gene            1..1000
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /note="TM2 domain containing 1"
                     /db_xref="GeneID:362545"
                     /db_xref="RGD:1305442"
     exon            1..205
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..665
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /note="beta-amyloid binding protein; TM2 domain-containing
                     protein 1"
                     /codon_start=1
                     /product="TM2 domain-containing protein 1 precursor"
                     /protein_id="NP_001102140.1"
                     /db_xref="GeneID:362545"
                     /db_xref="RGD:1305442"
                     /translation="MAAAWPAGRASPAAGPPALLRTLWLVTVAAGHCGAAASGAVGGE
                     ETPKCEDLRVGQYICKEPKINDATQEPVNCTNYTAHVQCFPAPNITCKDLSGNETHFT
                     GSEVGFLKPISCRNVNGYSYKVAVALSLFLGWLGADRFYLGYPALGLLKFCTVGFCGI
                     GSLIDFVLISMQIVGPSDGSSYIIDYYGTRLTRLSVTNETFRKTQLYP"
     exon            206..279
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            280..388
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            389..480
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            481..554
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            555..683
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /inference="alignment:Splign:2.1.0"
     exon            684..1000
                     /gene="Tm2d1"
                     /gene_synonym="Bbp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggcggaa ccggaagcgc gaggacgcgg tgcccaacat ggcggccgcc tggcccgcgg
       61 gtcgggcttc tccagcggcg gggcctccgg ccctcctccg cactctgtgg ctcgtgacgg
      121 tcgccgcggg acattgtggg gctgctgcct ctggcgctgt cggaggcgag gagacgccca
      181 agtgtgagga cctcagagtg ggacaatata tttgtaaaga accaaaaata aatgatgcta
      241 cgcaagaacc agttaattgt acaaactaca cagctcatgt tcaatgtttt ccagcaccca
      301 acataacttg taaggatttg agtggtaatg aaacacattt tactggaagt gaagttggtt
      361 ttctcaagcc catatcttgc cgaaatgtga atggctattc atacaaagtg gcagttgcac
      421 tatctctttt tttgggatgg ctgggagcag atcgatttta cctcggatat cctgccttag
      481 gcttgttaaa gttttgcact gtgggatttt gcggaattgg gagcctaatt gatttcgtcc
      541 ttatttcaat gcagatcgtc ggcccttcgg atgggagtag ttacattata gactattatg
      601 gaaccagact cacgagactc agcgttacta atgagacatt tagaaaaaca cagttgtatc
      661 catgagtgtt tgaaagagga acagatttga gcctccctga tttcaatcaa gagccctgtg
      721 tgtggaattc cagatttcct tttcctttag tatcacttta tgggttctag atgatgtttg
      781 acatgtgctc aaccttgatt tgttgattta gttagagtat actattccta gatttattta
      841 atagtctttc ttaaaatcag tatactatgt ttcgagggct tctgtctcta tgagacagct
      901 agtctatcac tttgttacta ttgtattact gtcatgtcct ttacacgtca cttgtcattt
      961 ttatttgtga aaaataaaaa gataacttat tcacatttga
//
