LOCUS       NM_001109166            2000 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus T-cell leukemia, homeobox 1 (Tlx1), mRNA.
ACCESSION   NM_001109166 XM_001057997 XM_574674
VERSION     NM_001109166.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2000)
  AUTHORS   Brendolan A, Ferretti E, Salsi V, Moses K, Quaggin S, Blasi F,
            Cleary ML and Selleri L.
  TITLE     A Pbx1-dependent genetic and transcriptional network regulates
            spleen ontogeny
  JOURNAL   Development 132 (13), 3113-3126 (2005)
   PUBMED   15944191
  REMARK    Erratum:[Development. 2005 Aug;132(15):3575]
REFERENCE   2  (bases 1 to 2000)
  AUTHORS   Qian Y, Shirasawa S, Chen CL, Cheng L and Ma Q.
  TITLE     Proper development of relay somatic sensory neurons and D2/D4
            interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1
  JOURNAL   Genes Dev 16 (10), 1220-1233 (2002)
   PUBMED   12023301
REFERENCE   3  (bases 1 to 2000)
  AUTHORS   Kanzler B and Dear TN.
  TITLE     Hox11 acts cell autonomously in spleen development and its absence
            results in altered cell fate of mesenchymal spleen precursors
  JOURNAL   Dev Biol 234 (1), 231-243 (2001)
   PUBMED   11356032
REFERENCE   4  (bases 1 to 2000)
  AUTHORS   Dube ID, Kamel-Reid S, Yuan CC, Lu M, Wu X, Corpus G, Raimondi SC,
            Crist WM, Carroll AJ, Minowada J et al.
  TITLE     A novel human homeobox gene lies at the chromosome 10 breakpoint in
            lymphoid neoplasias with chromosomal translocation t(10;14)
  JOURNAL   Blood 78 (11), 2996-3003 (1991)
   PUBMED   1683261
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473986.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001057997.1, XM_574674.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN09345331,
                              SAMN11044071 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2000
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..2000
                     /gene="Tlx1"
                     /gene_synonym="RGD1563655"
                     /note="T-cell leukemia, homeobox 1"
                     /db_xref="GeneID:499361"
                     /db_xref="RGD:1563655"
     exon            1..778
                     /gene="Tlx1"
                     /gene_synonym="RGD1563655"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..1203
                     /gene="Tlx1"
                     /gene_synonym="RGD1563655"
                     /codon_start=1
                     /product="T-cell leukemia homeobox protein 1"
                     /protein_id="NP_001102636.1"
                     /db_xref="GeneID:499361"
                     /db_xref="RGD:1563655"
                     /translation="MEHLGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGE
                     YGLGCLVGGAYTYGGGGSAAGAGAGGTGAYGTGGPGGPGGPAGGGGGACSMGPLAGSY
                     NVNMALAGGPGPGGGGGGAGAGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTV
                     PSVPAVPGVNNLTGLTFPWMESNRRYTKDRFTGHPYQNRTPPKKKKPRTSFTRLQICE
                     LEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANR
                     ILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE"
     exon            779..980
                     /gene="Tlx1"
                     /gene_synonym="RGD1563655"
                     /inference="alignment:Splign:2.1.0"
     exon            981..2000
                     /gene="Tlx1"
                     /gene_synonym="RGD1563655"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaaggagaa gccggagagg ggaagaatac agctctccct ctctcctccc cctcccccct
       61 actttggccc ttctgcgcac ttcgccttca agtctcaccg cagcctggag cggcgattgc
      121 ctccgcgccc ctactcgctg cccgggtagt ccagcgcagc gagcgcccgc gcccgggccc
      181 ccgcgtgggg ccggggccag catggagcac ctgggtccgc accatctcca cccgggccac
      241 gcggagccca tcagcttcgg catcgaccag atcctcaaca gcccggacca gggcggctgc
      301 atggggcccg cctcgcgcct ccaggacgga gaatacggcc ttggctgttt ggtcggaggc
      361 gcctacactt atggcggagg gggttccgcc gctggagcgg gggccggggg cacaggcgct
      421 tacggcaccg gtggcccggg tggtcccgga ggcccggcgg gcggtggcgg aggtgcctgc
      481 agcatgggcc cactggccgg ctcctacaac gtgaacatgg ccttggcggg cggcccgggt
      541 ccgggaggcg gcggcggtgg cgcgggtgcc ggtggcgccg gtgcgctgag cgctgcaggg
      601 gtgatccggg tgcccgcgca caggccgcta gctggagctg tggcccatcc ccagcccctg
      661 gccaccggct tgcctactgt gccctctgtg cctgcggtgc cgggtgtcaa caacctcacc
      721 ggcctcacct tcccctggat ggagagtaac cgcagataca caaaggacag gttcacaggt
      781 cacccctatc agaaccggac gccccctaag aagaagaagc cgcgtacatc cttcacacgc
      841 ctgcagatct gtgagctgga aaagcgcttc caccgccaga agtacttggc ttcggcggag
      901 cgcgctgctc tggccaaagc gctcaaaatg accgatgcgc aagtcaaaac ctggttccag
      961 aacaggagga cgaaatggag gcgacagaca gcagaggagc gtgaggccga gaggcagcag
     1021 gcgaaccgca tcctcttgca gctgcagcag gaggccttcc agaagagcct ggcccagccg
     1081 ctgcctgcag acccactgtg cgtgcacaac tcgtcgctct ttgccctgca gaacctgcag
     1141 ccgtggtctg acgactccac caaaatcact agcgtcacgt ccgtggcttc ggcctgtgag
     1201 tgaggaccca agcccaattg agggctatcc ggagaaccag aactctcgat accttttctg
     1261 agtgcacgca ggaagggaac gggcttctca gcaaggctcc cagcaccgcc tcacacccct
     1321 gaggacactg tccggtcttc ggtggaagag ggtggagata gaggcagaag cctgcgtgat
     1381 cctgtctcac tctggaactg ttcagaatct cctctttttc tctatttcat aaaatttact
     1441 ctgattttaa catgggacag agagacccaa gggatgtagg gtcctgaagg cttctgggat
     1501 ccccaggcag ccatccgtac taaggctgga aacctctcta ttcctttcct cctacatcca
     1561 cacagaggtg ataccactgt ccctcctggc gtcaccttag agccacatgc aggggccgat
     1621 ggcagagcat cacagcacat acaggatcac aacaaatgac ccttgccgtt gggcacagtc
     1681 tagggtgaca cttggactcg cccaaacagc acggacctcc tcttactcga acacaaggcc
     1741 atagtcacat agtgacacac cagcccacac acaacagcta aacctggcct gtcaggtccc
     1801 tcgccacaca tcccagcggc acccaggtat gcacagacag gctttcacac aaatgcagcc
     1861 catttctcca gatcctgttt ggggaggggg gtaagttatg cacttataag ttatgcactt
     1921 ataaggtgtt ttctgtgtaa ccattttata aagtgcttgt gtaatttatg tggaaaaata
     1981 ataaaaccct cccgatcagg
//
