LOCUS       NM_001144779            3219 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus toll-like receptor 11 (Tlr11), mRNA.
ACCESSION   NM_001144779 XM_001074442 XM_573751
VERSION     NM_001144779.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Biswas,B., Narmadha,G., Choudhary,M., French,F.S., Hall,S.H. and
            Yenugu,S.
  TITLE     Identification of Toll-like receptors in the rat (Rattus
            norvegicus): messenger RNA expression in the male reproductive
            tract under conditions of androgen variation
  JOURNAL   Am J Reprod Immunol 62 (4), 243-252 (2009)
   PUBMED   19703144
REFERENCE   2  (bases 1 to 3219)
  AUTHORS   Banas,M.C., Banas,B., Hudkins,K.L., Wietecha,T.A., Iyoda,M.,
            Bock,E., Hauser,P., Pippin,J.W., Shankland,S.J., Smith,K.D.,
            Stoelcker,B., Liu,G., Grone,H.J., Kramer,B.K. and Alpers,C.E.
  TITLE     TLR4 links podocytes with the innate immune system to mediate
            glomerular injury
  JOURNAL   J Am Soc Nephrol 19 (4), 704-713 (2008)
   PUBMED   18256364
REFERENCE   3  (bases 1 to 3219)
  AUTHORS   Palladino,M.A., Johnson,T.A., Gupta,R., Chapman,J.L. and Ojha,P.
  TITLE     Members of the Toll-like receptor family of innate immunity
            pattern-recognition receptors are abundant in the male rat
            reproductive tract
  JOURNAL   Biol Reprod 76 (6), 958-964 (2007)
   PUBMED   17314314
REFERENCE   4  (bases 1 to 3219)
  AUTHORS   Zhang,D., Zhang,G., Hayden,M.S., Greenblatt,M.B., Bussey,C.,
            Flavell,R.A. and Ghosh,S.
  TITLE     A toll-like receptor that prevents infection by uropathogenic
            bacteria
  JOURNAL   Science 303 (5663), 1522-1526 (2004)
   PUBMED   15001781
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Oct 11, 2012 this sequence version replaced NM_001144779.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ230537.1, FQ190487.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-132               JAXUCZ010000015.1  26018987-26019118
            133-3219            JAXUCZ010000015.1  26020340-26023426
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..3219
                     /gene="Tlr11"
                     /gene_synonym="RGD1564460"
                     /note="toll-like receptor 11"
                     /db_xref="GeneID:498491"
                     /db_xref="RGD:1564460"
     exon            1..132
                     /gene="Tlr11"
                     /gene_synonym="RGD1564460"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..2921
                     /gene="Tlr11"
                     /gene_synonym="RGD1564460"
                     /EC_number="3.2.2.6"
                     /codon_start=1
                     /product="toll-like receptor 11"
                     /protein_id="NP_001138251.2"
                     /db_xref="GeneID:498491"
                     /db_xref="RGD:1564460"
                     /translation="MLKESMPKMERHLFHSVLLILILLTLVSLNLTGLAWTIPDCIIA
                     DSLLFPNLSSYIPFCTLAPRLHLLASCSNVKNINQTLEKVPRNTEVLCLQGMVPTLPA
                     NAFDGFYSLQLLRLQLGTTNITSRTFQGLDQLQYLFFEHHAPCCLSLFLPPDSLESLR
                     SLSSLSFQGYCLTYSHSIYLPTTLRHLTMRNSCLTKLQELQRLFPDLLLGASSTPNTK
                     PRTPFLEVLDLSYNLQLKQAGIRDLYGLTLHSLILDGTPLRALDLTSSGLLHLHFLSL
                     VGTGIEKLPASVTGFSELCALDLGKNQIQNILGNGDILGLKALKFLSLHDNHLQSLPV
                     RFLRTLPQLQKLNLSMNKLGPILELPEGLFSTNLTVLDLSHNQLCEIPRGNFSFLSQL
                     QELWLSGNNISSLSNESLQGLRWLRTLDLSWNQIKVLKPGWLSHLPALTTLNLLGTYL
                     EHISGTQLQGPKMLRHLQLGSFPTLEIYRLWFPMLLSLEIQAETYIQFMVPSGEPFLF
                     LENLTLETSNLLLEPKTTTIHFPSLRRLTLRGYSIFLSTSQLQSFFPPQLPLLEYFFV
                     WCRNDDAVDLHLFEMPRLRVLELGNLNFFYESSTVKLEMLLNEVPQLQVLALSHLNLK
                     NLSVSSFKGLQSLKLLLLNSERALEMNSNLQELIPQIPQYVYFSDVTFACQCETSWLE
                     SWATRAPNTFVYGLEKPICMANASDYSKTLLFSFLATNCPHGTEFWGFLTSFSLLLLL
                     IILPLISCHKWSWLHHLWTLFHTCWWKLGGHRLRGQFNYDVFISYCEEDQDWVLEELV
                     PVLEKAPPEGEGLRLCLPARDFGIGNDRMESMIASMGKSRAILCVLTGQALASPWCNL
                     ELRLATYHLIARPGTTCLLLLFLEPLDRQKLHSYHRLSRWLQKEDYFDLSQGKMEWNT
                     FCEQLKQRLRKARKERED"
     exon            133..3219
                     /gene="Tlr11"
                     /gene_synonym="RGD1564460"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acatatcacc aataacatag ttctgtgcag cagagcaggt ggagggaaga gaaaggtttt
       61 cctctctggc tatgggtgat gaaagagaac tctcttgaga acgtgaatat ctccaccacc
      121 tcatgctcaa agaatcaatg ccaaagatgg aaagacatct gttccactct gttctcctca
      181 ttctgatact actgactttg gtgagcctta acttgaccgg cttggcatgg actatccctg
      241 attgcatcat agcagacagc ttgttatttc ctaacctttc ctcctacatc ccattctgta
      301 ccttggcccc aaggctgcat cttttggcat cttgttccaa tgttaaaaac ataaatcaaa
      361 ccctagaaaa agtgcccaga aatacagagg tgctttgcct ccagggcatg gttcctactc
      421 tgccagcaaa tgcctttgat ggcttctact ccctacagct tctaaggctt caattgggta
      481 caaccaacat cacatctagg actttccaag gcctggacca gctacagtac cttttttttg
      541 agcatcacgc tccctgttgc ctaagtctgt tcctccctcc agatagttta gagtctctca
      601 gatcccttag tagtctttcc tttcaaggat actgcctgac ttatagccac agcatctact
      661 tgccaaccac tctcaggcat ctaaccatga ggaacagctg cctgacaaag ttgcaggaac
      721 ttcaaagact cttcccagat cttctgctgg gtgcctcttc tacacccaat accaaaccaa
      781 ggacaccctt tctagaggtg ctggatttat cttacaacct tcagctgaag caggcaggta
      841 tcagagactt gtatggcctc acactccatt ccctaatatt ggatggcacc ccactaagag
      901 cacttgatct cacaagctca ggactgctcc acttgcactt cctctccctc gtgggtacgg
      961 gtatagaaaa actgcctgca agtgtgaccg gcttctctga gctttgtgca cttgatcttg
     1021 ggaagaatca aatccaaaac atcttaggaa atggagatat cctaggtttg aaagccctga
     1081 aattcctcag ccttcatgat aaccatctgc aatcacttcc cgtcaggttt ctgcgtactc
     1141 taccccagct tcagaagctc aacctatcta tgaataagct tggcccaatc ttggagcttc
     1201 cagaaggact ctttagcaca aatctaacag tgctagatct gtcccacaat caactctgtg
     1261 aaataccccg tgggaatttc tccttccttt cacagctcca ggagctctgg ctgagtggca
     1321 ataacatctc tagtttatcc aatgagagcc tgcagggact gaggtggctg aggacactag
     1381 acttgagttg gaatcaaatt aaagtactca aaccaggatg gctctctcat cttcctgcgc
     1441 tgactacctt gaaccttctg ggcacttact tagagcatat ctcaggcaca caacttcagg
     1501 gtcccaagat gctaagacat ctacaactgg gttcttttcc aacgctggaa atatatcgtc
     1561 tctggttccc aatgctcctc agcttagaaa tacaagcaga aacatatatc cagtttatgg
     1621 ttccaagcgg agagccattc ttattcttgg agaaccttac cttagagact tccaatctgt
     1681 tactggaacc aaaaaccacc acaattcatt ttccctccct acgtcgcctc accttgcgtg
     1741 gctacagtat cttcttgtca accagtcaac tccagagttt cttcccacca cagcttcccc
     1801 tcctggagta cttctttgta tggtgtagaa atgacgatgc agtagacctc catctattcg
     1861 agatgcccag gctgcgtgtg ctagagctgg gcaaccttaa ttttttctac gagtcaagta
     1921 cggtgaagct agagatgctg ctcaacgagg tgcctcagtt acaggtactg gcattgagtc
     1981 acctaaatct caagaacctc tctgtgtcca gctttaaggg tttgcagagc ctcaaactgc
     2041 tgctgctcaa ctccgaaaga gccctggaga tgaacagcaa ccttcaggag ttaattcctc
     2101 agattcctca gtatgtttat ttctcagatg tcacctttgc ctgccagtgt gaaacttcct
     2161 ggctggagtc ttgggctaca cgggccccaa acactttcgt ttatgggctg gaaaaaccca
     2221 tctgcatggc taatgcctcc gactactcca aaactctact gttctccttc cttgctacca
     2281 attgcccaca tggcactgag ttttggggct tcctcaccag tttctccctg ctgcttctgc
     2341 tgataatcct tcctctaatt agctgtcata aatggtcctg gctccatcac ctctggacac
     2401 tctttcacac ctgttggtgg aaattaggcg gacatagact cagagggcaa ttcaactacg
     2461 atgtctttat atcctattgt gaagaggacc aagattgggt gctggaagaa ctggttccgg
     2521 ttttggagaa agcccctcct gaaggtgagg gcttgaggct ctgcttgcct gccagggact
     2581 ttgggattgg aaatgacagg atggaatcca tgattgccag catgggcaaa agcagagcca
     2641 tcctctgtgt gctcacaggt caggccttag caagtccctg gtgcaatcta gagttaagac
     2701 tggccactta ccatttgata gccaggcccg ggaccacttg ccttctgctg ctgtttctgg
     2761 agccccttga taggcagaag ctccatagtt accaccgcct ctcccgatgg ctccagaagg
     2821 aggactattt tgatttgtcc caagggaaaa tggagtggaa cactttctgt gagcaactga
     2881 agcaacggct cagaaaagct agaaaagaaa gagaagatta agggctgtct gggatgttgc
     2941 tgtgcagaaa atcctttcag cagcagcaag aatgctctct catcactaga gcacggactc
     3001 aaaagtgggg caaaaatagt atatttttaa atgctatatt aaatgctact ggttgggaag
     3061 tcttttaaaa cactggaaaa tattcattta gaaaacaatt cttttacgtg ctagtgcatt
     3121 ccagcacgag atattgctca gcacacaagg caaagaggtt tgtgcaatcc tgtgtatgtt
     3181 ttttacaaaa cttttcaaaa taaatccatc ctgctacta
//
