LOCUS       NM_001146035            2436 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus toll-like receptor 10 (Tlr10), mRNA.
ACCESSION   NM_001146035 XM_001078345 XM_223422
VERSION     NM_001146035.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2436)
  AUTHORS   Godfroy,J.I. 3rd, Roostan,M., Moroz,Y.S., Korendovych,I.V. and
            Yin,H.
  TITLE     Isolated Toll-like receptor transmembrane domains are capable of
            oligomerization
  JOURNAL   PLoS One 7 (11), e48875 (2012)
   PUBMED   23155421
REFERENCE   2  (bases 1 to 2436)
  AUTHORS   Kormann,M.S., Depner,M., Hartl,D., Klopp,N., Illig,T., Adamski,J.,
            Vogelberg,C., Weiland,S.K., von Mutius,E. and Kabesch,M.
  TITLE     Toll-like receptor heterodimer variants protect from childhood
            asthma
  JOURNAL   J Allergy Clin Immunol 122 (1), 86-92 (2008)
   PUBMED   18547625
REFERENCE   3  (bases 1 to 2436)
  AUTHORS   Hasan,U., Chaffois,C., Gaillard,C., Saulnier,V., Merck,E.,
            Tancredi,S., Guiet,C., Briere,F., Vlach,J., Lebecque,S.,
            Trinchieri,G. and Bates,E.E.
  TITLE     Human TLR10 is a functional receptor, expressed by B cells and
            plasmacytoid dendritic cells, which activates gene transcription
            through MyD88
  JOURNAL   J Immunol 174 (5), 2942-2950 (2005)
   PUBMED   15728506
  REMARK    GeneRIF: A complete TLR10 sequence is detected in the rat genome,
            indicating that a functional copy may be preserved in this species.
REFERENCE   4  (bases 1 to 2436)
  AUTHORS   Tantisira,K., Klimecki,W.T., Lazarus,R., Palmer,L.J., Raby,B.A.,
            Kwiatkowski,D.J., Silverman,E., Vercelli,D., Martinez,F.D. and
            Weiss,S.T.
  TITLE     Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism
            frequencies and preliminary association with the diagnosis of
            asthma
  JOURNAL   Genes Immun 5 (5), 343-346 (2004)
   PUBMED   15266299
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from FJ755908.1.
            
            On or before Mar 27, 2009 this sequence version replaced
            XM_223422.4, XM_001078345.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: FJ755908.1 [ECO:0000345]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2436
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..2436
                     /gene="Tlr10"
                     /note="toll-like receptor 10"
                     /db_xref="GeneID:305355"
                     /db_xref="RGD:1311569"
     CDS             1..2436
                     /gene="Tlr10"
                     /EC_number="3.2.2.6"
                     /codon_start=1
                     /product="toll-like receptor 10"
                     /protein_id="NP_001139507.1"
                     /db_xref="GeneID:305355"
                     /db_xref="RGD:1311569"
                     /translation="MRLISSIYTLYNIIMSTEAWAPRPTDERELISNYSNMALRKVPP
                     DVTPATTILDLSYNLLYQFQSSDFHSFSKLRFLILCHNSIQQLDTKIFDLNKELSYLD
                     LSYNRLQSITWSSLVDLRHLDLSFNDFDTLPACEEIGNMRHLETLGLSGAKIQRSDLQ
                     KIANLQFSTVFIGLNTLSHYEEGSLPVLNTTVLHIVLPMAANFWVLLCDGMKTSKVVE
                     MSNIGGKSQFVSYETPRTLSVENTKASTLIFHKVDLLWDDLLHVFQFVWQTSVECFQI
                     QDLTFGGMASRDHSSFDYSNTVMKAVILESIHFRIFFIPQNKIYLFFTQMDLENLTIS
                     DAQMPHLLFPSHPQSFQHLNFANNILTDDLFKNPIQMPYLKTLVLRGNQLETLSLVSL
                     FANHTSLLHLDLSQNLLQHGNGEKCMWPDTLILLNLSSNKFDGSVFRCLPKSIQTLDL
                     NNNKIRAVPKEIIYLKSLRELSIAFNFLTDLPGCDHFKRLSSLNIEMNLILSPSLDFF
                     QSCQEVKTLNAGRNPFRCICEFRDFIWLEKHSKGLMSEWPDSYACEYPLSLKGTPLKD
                     VYLPELACNTTLLIVTIVLVILVLGLVVAFCILKFDMLWYLRVLAQCIRTQHRVRKTV
                     REERKRSVQFHAFISYAAHDSVWVKNELIPNLETEDGSVLLCLPERNFDPDRSIAENI
                     ISCTEKSYKSIFVLSPNFVQNGWCHNELYLAHHNPFRDNYDYIIPILLEPIPSYCVPT
                     KFPKLKALLEKKVYLEWPKDRRKHGLFWANLRAAINVNLSDTRGRCELQTFTKPNADC
                     QGSTISLVRTDSF"
     exon            1..2436
                     /gene="Tlr10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgagactca tcagcagcat ctataccctt tataacatca ttatgtcaac agaagcctgg
       61 gctccaagac ccacagatga aagggaactg atctccaact actccaacat ggctttaagg
      121 aaggttcccc cagatgtgac cccagccaca accatactgg atttatccta caacctcctc
      181 tatcaattcc agagctcaga tttccactcc ttctccaaac tgcgttttct gatcctgtgc
      241 cataacagca tccaacagct ggacaccaag atctttgacc ttaacaagga gctaagctat
      301 ttagacttgt cttacaatag actacagtcc atcacttggt cttccttggt agatctcaga
      361 catttagatc tttcttttaa cgacttcgat actctgcctg cctgtgagga gattggcaac
      421 atgcgacatc tggaaacctt aggtttgagt ggggccaaaa tccaaagatc agatctccag
      481 aaaattgcta atttgcaatt cagcactgtg ttcatagggc tgaatactct ttctcactat
      541 gaagaaggca gcctgcctgt cctaaacacg acagtgcttc acatagtttt accaatggct
      601 gctaacttct gggtgcttct gtgtgatgga atgaagactt caaaggtagt cgaaatgtca
      661 aacataggtg gcaagagcca gtttgtaagt tatgagactc cgagaactct ttctgtggag
      721 aataccaagg cgtccactct tatattccat aaagttgacc tgctctggga tgaccttctc
      781 cacgtttttc agtttgtgtg gcagacttca gtggaatgct tccagattca ggacctgact
      841 tttggaggga tggctagtcg ggaccacagt tcatttgact actcaaatac cgtaatgaaa
      901 gctgtaatct tggagagcat acatttcaga atctttttca ttccccagaa taaaatctac
      961 ttgtttttca cccaaatgga tttagaaaac ctgacgatat cagatgcaca aatgccacat
     1021 cttctcttcc ctagtcaccc ccaaagtttc caacatttaa attttgccaa taacatctta
     1081 acagatgacc tgtttaaaaa ccccatccag atgccttatc tgaaaactct cgttttgagg
     1141 ggcaaccaac tggagactct ttctctagtg agtctctttg ccaaccacac gtccttgctt
     1201 cacctggatc tgagccagaa cctattgcaa catggaaacg gggagaaatg catgtggccc
     1261 gacaccttga tcctcttgaa cttgtcatcc aataaatttg atggttctgt tttcagatgt
     1321 ttgcctaaaa gtatccagac acttgatctg aacaataaca aaattcgagc agtccctaaa
     1381 gagattatat acctaaaatc tttacgagag ctaagtattg cttttaattt tctgactgac
     1441 ctccctgggt gtgatcactt caaacggctc tctagtctga acattgaaat gaatttgatt
     1501 ctcagcccat ctctggattt tttccagagc tgccaggagg taaagactct aaacgcaggg
     1561 cgaaatccat tccggtgtat ctgtgaattt agagacttca tttggcttga gaaacattcc
     1621 aagggcctga tgtctgaatg gccagactcc tacgcctgcg aatacccttt gagtctaaag
     1681 gggactccat taaaagatgt ttatcttccc gaattagctt gcaacacaac tttgctgatt
     1741 gtcaccattg tgctggttat cctggttctg ggtttggttg tagcattctg cattctaaaa
     1801 tttgacatgc tttggtatct cagggtgctg gcccagtgca tccggacaca gcatagggtt
     1861 aggaagacag ttcgagagga gcgtaagaga agtgtacagt tccatgcatt tatctcctac
     1921 gctgcacatg attctgtctg ggtgaagaat gaactgattc ccaatctgga gacagaagat
     1981 ggctctgtct tgctttgtct tcccgagagg aactttgacc ctgacaggag cattgctgaa
     2041 aatattataa gctgcactga gaaaagctat aagtccatct ttgtgctgtc ccccaacttt
     2101 gtgcagaatg ggtggtgcca taatgaactc tatctggccc accacaatcc tttccgtgac
     2161 aattatgatt acatcattcc catcttacta gaacccattc cctcctactg tgttcctacc
     2221 aagttcccta agctgaaagc tcttttggaa aagaaagtat acttagagtg gcccaaggac
     2281 aggcgcaaac atgggctttt ttgggcaaac cttcgagctg ccattaacgt aaatttatca
     2341 gacacaaggg gaaggtgtga actacagaca ttcacaaagc ctaacgcgga ttgccaaggt
     2401 tctaccatct ctctggtaag aacagacagc ttctaa
//
