LOCUS       NM_001106296            1729 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus TLC domain containing 3B (Tlcd3b), mRNA.
ACCESSION   NM_001106296 XM_001077731 XM_215066
VERSION     NM_001106296.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1729)
  AUTHORS   Yamashita-Sugahara Y, Tokuzawa Y, Nakachi Y, Kanesaki-Yatsuka Y,
            Matsumoto M, Mizuno Y and Okazaki Y.
  TITLE     Fam57b (family with sequence similarity 57, member B), a novel
            peroxisome proliferator-activated receptor gamma target gene that
            regulates adipogenesis through ceramide synthesis
  JOURNAL   J Biol Chem 288 (7), 4522-4537 (2013)
   PUBMED   23275342
  REMARK    Erratum:[J Biol Chem. 2020 Apr 10;295(15):5176. PMID: 32277067]
REFERENCE   2  (bases 1 to 1729)
  AUTHORS   Thompson PJ, Norton KA, Niri FH, Dawe CE and McDermid HE.
  TITLE     CECR2 is involved in spermatogenesis and forms a complex with SNF2H
            in the testis
  JOURNAL   J Mol Biol 415 (5), 793-806 (2012)
   PUBMED   22154806
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC161920.1.
            
            On Apr 13, 2008 this sequence version replaced NM_001106296.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161920.1, CB605876.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1729
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q36"
     gene            1..1729
                     /gene="Tlcd3b"
                     /gene_synonym="Fam57b; RGD1308215"
                     /note="TLC domain containing 3B"
                     /db_xref="GeneID:293493"
                     /db_xref="RGD:1308215"
     exon            1..287
                     /gene="Tlcd3b"
                     /gene_synonym="Fam57b; RGD1308215"
                     /inference="alignment:Splign:2.1.0"
     CDS             163..990
                     /gene="Tlcd3b"
                     /gene_synonym="Fam57b; RGD1308215"
                     /note="family with sequence similarity 57, member B; TLC
                     domain ceramide synthase 3B"
                     /codon_start=1
                     /product="ceramide synthase"
                     /protein_id="NP_001099766.2"
                     /db_xref="GeneID:293493"
                     /db_xref="RGD:1308215"
                     /translation="MLTPMVAGGVVFPGLFLLSKNTLQRLPQLRWEEADAVIVSARLV
                     SSVQAIMASTAGYIVSTSCKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQV
                     KGHGGEDGTPRALGSTWAVVRGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLG
                     CMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRH
                     AGLPLLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFRPRGSPPRSPCQTQD"
     exon            288..371
                     /gene="Tlcd3b"
                     /gene_synonym="Fam57b; RGD1308215"
                     /inference="alignment:Splign:2.1.0"
     exon            372..606
                     /gene="Tlcd3b"
                     /gene_synonym="Fam57b; RGD1308215"
                     /inference="alignment:Splign:2.1.0"
     exon            607..702
                     /gene="Tlcd3b"
                     /gene_synonym="Fam57b; RGD1308215"
                     /inference="alignment:Splign:2.1.0"
     exon            703..1705
                     /gene="Tlcd3b"
                     /gene_synonym="Fam57b; RGD1308215"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcccatcct gtccccgccc tggccccttt gtgcctcccc ctccctcttt ctctctccct
       61 cactagcttg gccatccctt ctccacctcc aactccctcc ctcagtttgg ccttcctgtc
      121 ctttctggac cctctggtct ccctgcctgg gtccaagtca ccatgcttac cccaatggtg
      181 gctggggggg tggtgttccc cggactcttc ctcctatcca agaacacgct ccagaggctg
      241 ccccagctgc gctgggagga ggccgacgca gtcattgtct ccgccaggct ggtgtcctct
      301 gtccaagcca tcatggcctc cacagctggc tacatagtct ccacatcctg caagcacatc
      361 atagatgacc agcactggct gtcctcggcc tacacacagt ttgcagttcc ctacttcatc
      421 tacgacatct atgccatgtt cctttgccac tggcacaagc accaggttaa agggcatgga
      481 ggagaagacg ggacgccccg agccctgggc agtacctggg ccgtggtgcg tggctacctg
      541 cacaaggagt tcctcatggt gctccaccac gcggccatgg tgctggtgtg cttcccactc
      601 tctgtggtgt ggagacaagg caagggagat ttctttctag gctgcatgtt gatggccgag
      661 gtcagcacac ctttcgtctg cctgggcaag atcctcatcc agtacaagca gcagcacaca
      721 ttgctgcaca aggtgaatgg agccctgatg ctactcagct tcttgtgctg ccgggtgctg
      781 ctcttccctt acctgtactg ggcctacggg cgccacgctg gcctgcccct gctctcagtg
      841 cccatggcta tcccggccca cgtcaacttg ggcgctgcgc tactcctcgc accccagctc
      901 tactggttct tcctcatttg ccgcggggcc tgccgcctct tccgaccccg aggttcccca
      961 ccacgctctc cttgtcagac ccaggactga ggctaggccc tggaaccccc caccctccct
     1021 ccccggcccc tgtggagaca gtgctttggg gctaatcggt gtgtgtgtgg gggggtgaga
     1081 gccaggagtc ccttgccttg acagccccaa gacagatgga cttagaataa ggaggagcta
     1141 tatacccttg ggagctgagg tcagattggc aggcaggaag agaggggacc gggacgaaga
     1201 gcctcttctt gcctctgtgc taacaaaatg aaagggaatg ggaggagatg gggctcactg
     1261 ggaccaagga gtcatgggac atgggggtgg ccccgctgcc aaggacatcc tagccctgct
     1321 gctgcaaatc cctctctgct ctccatcacc cgggagagag aagacaccct aactcacccc
     1381 atatgggccc tgagagggca ggagaccccc acagctcctt cctgtggaga ccaatctgag
     1441 gaatcttatt tatttattca cccacatcaa actaatttgt tggggtgagg ggagggaggc
     1501 agttgctccc ctacaaccct tccagcgctg agcagccctg ggggcaggcg ccaggccagt
     1561 cccttctgtc aggggcacat ttagccctcg gccccggctt gtccctggtg ctacaggcca
     1621 atcgcggctt cctccagtct gggggccaca gaccccggga ggtgctttta cagaccgcta
     1681 ataaagacga tcttcctgaa cgccaaaaaa aaaaaaaaaa aaaaaaaaa
//
