LOCUS       NM_001008343            1415 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus translocase of inner mitochondrial membrane 21
            (Timm21), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001008343 XM_225675
VERSION     NM_001008343.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1415)
  AUTHORS   Wenz,L.S., Opalinski,L., Wiedemann,N. and Becker,T.
  TITLE     Cooperation of protein machineries in mitochondrial protein sorting
  JOURNAL   Biochim Biophys Acta 1853 (5), 1119-1129 (2015)
   PUBMED   25633533
  REMARK    Review article
REFERENCE   3  (bases 1 to 1415)
  AUTHORS   Schulz,C., Schendzielorz,A. and Rehling,P.
  TITLE     Unlocking the presequence import pathway
  JOURNAL   Trends Cell Biol 25 (5), 265-275 (2015)
   PUBMED   25542066
  REMARK    Review article
REFERENCE   4  (bases 1 to 1415)
  AUTHORS   Mick,D.U., Dennerlein,S., Wiese,H., Reinhold,R., Pacheu-Grau,D.,
            Lorenzi,I., Sasarman,F., Weraarpachai,W., Shoubridge,E.A.,
            Warscheid,B. and Rehling,P.
  TITLE     MITRAC links mitochondrial protein translocation to
            respiratory-chain assembly and translational regulation
  JOURNAL   Cell 151 (7), 1528-1541 (2012)
   PUBMED   23260140
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085823.1.
            
            On Dec 16, 2004 this sequence version replaced XM_225675.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085823.1, BQ193395.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.3"
     gene            1..1415
                     /gene="Timm21"
                     /gene_synonym="RGD1307279"
                     /note="translocase of inner mitochondrial membrane 21"
                     /db_xref="GeneID:307210"
                     /db_xref="RGD:1307279"
     exon            1..511
                     /gene="Timm21"
                     /gene_synonym="RGD1307279"
                     /inference="alignment:Splign:2.1.0"
     CDS             214..951
                     /gene="Timm21"
                     /gene_synonym="RGD1307279"
                     /note="TIM21-like protein, mitochondrial; mitochondrial
                     import inner membrane translocase subunit Tim21;
                     translocase of inner mitochondrial membrane 21 homolog"
                     /codon_start=1
                     /product="mitochondrial import inner membrane translocase
                     subunit Tim21 precursor"
                     /protein_id="NP_001008344.1"
                     /db_xref="GeneID:307210"
                     /db_xref="RGD:1307279"
                     /translation="MICAFLRVVRHAEKLHGSLGRQLLLPHFVLTKACLKTQPLRWGL
                     REQKKTVQPRTVLGFTQKTFWTQGPDPRKAKEDSSKQVSINRNQREETGVSTSQKVKE
                     AGRDVTYLIVVLFGVSITGSLLYTIFKELFSSSSPNIIYGKALGKCRTHPEVISVFGE
                     PVKGYGEMSRRGRRQHVSFTEYANNGLKRIRVKFYIEGSEPGKQGTVHAEVEENPRSG
                     QFDFRYIFVDVAPKRSIVVEDNRFQQS"
     exon            512..574
                     /gene="Timm21"
                     /gene_synonym="RGD1307279"
                     /inference="alignment:Splign:2.1.0"
     exon            575..672
                     /gene="Timm21"
                     /gene_synonym="RGD1307279"
                     /inference="alignment:Splign:2.1.0"
     exon            673..746
                     /gene="Timm21"
                     /gene_synonym="RGD1307279"
                     /inference="alignment:Splign:2.1.0"
     exon            747..852
                     /gene="Timm21"
                     /gene_synonym="RGD1307279"
                     /inference="alignment:Splign:2.1.0"
     exon            853..1321
                     /gene="Timm21"
                     /gene_synonym="RGD1307279"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgaatgtca gtaggacggt aaatagggca ttttaattca agagagagaa aaaaaataaa
       61 gtgtacctaa cttctcttgt agattattca tcttgatatt cgcctgacac aggatgtaat
      121 gtgaatggtt tggtttcacg tcttgtccgc ctgagtgtgt ggattacgaa cctttagaag
      181 ttgcagttcg gaagtctcac agtgtttgtg aacatgattt gtgcttttct acgagttgtt
      241 cggcatgcgg agaagctgca cgggtcgttg ggcaggcagt tgttgttgcc acactttgta
      301 ctcaccaaag cttgcttgaa aacccagcct ttgagatggg ggctgcgaga gcagaagaaa
      361 acagtgcaac ctagaactgt ccttgggttc acccagaaaa ccttctggac acaaggaccg
      421 gacccccgga aagcaaagga ggacagtagc aagcaagtgt ctattaacag gaatcaaaga
      481 gaggaaaccg gtgtctcaac atctcagaaa gtgaaagaag ccgggagaga cgtcacctac
      541 ctgatagtgg tgctctttgg agtcagcatt acaggcagct tgttatatac gatcttcaaa
      601 gaactgtttt cctcatccag tcctaacatc atctatggga aagccttagg gaaatgcaga
      661 acacaccctg aggtgatcag tgtctttggc gagcctgtga aaggctatgg ggaaatgtcg
      721 agacgtgggc ggagacaaca tgtcagcttt actgaatatg caaacaacgg gctaaagcgc
      781 atccgtgtga agttctatat cgagggctct gagccaggga agcaaggaac ggtacacgca
      841 gaagtggaag agaacccgag gagtggccag tttgattttc gatatatatt tgtggacgtg
      901 gctcctaaaa gatctattgt tgttgaagat aaccgtttcc aacaaagtta aaagcctcaa
      961 gccagtgcag tgcttcctgc cgagaatgaa gggatccgtt ctcactgcga tcctcacaac
     1021 tctcttccag aatttgttca aaaaaacaag aataaagtat gtcacatgga aaggaggtgc
     1081 aatgtgagtg agtgttcatg agtttggaga agcagatctt tcttgtgaaa aatcatgaga
     1141 tgtagcaaat tctatattat ccttgacttg ccgatcatga ccgtatttca gctctacatt
     1201 catggtaaac ctttgttact aaaatttata caccacataa gtaaaacctt caatatttta
     1261 tgctatttaa tattgtatgg cttttatata atcaacagaa taaagattaa actaacaaaa
     1321 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1381 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
//
