LOCUS       NM_001389232             991 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus translocase of inner mitochondrial membrane 10B
            (Timm10b), transcript variant 2, mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001389232
VERSION     NM_001389232.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 991)
  AUTHORS   Vukotic,M., Nolte,H., Konig,T., Saita,S., Ananjew,M., Kruger,M.,
            Tatsuta,T. and Langer,T.
  TITLE     Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the
            TIM22 Protein Translocase in Mitochondria
  JOURNAL   Mol Cell 67 (3), 471-483 (2017)
   PUBMED   28712724
REFERENCE   3  (bases 1 to 991)
  AUTHORS   Muhlenbein,N., Hofmann,S., Rothbauer,U. and Bauer,M.F.
  TITLE     Organization and function of the small Tim complexes acting along
            the import pathway of metabolite carriers into mammalian
            mitochondria
  JOURNAL   J Biol Chem 279 (14), 13540-13546 (2004)
   PUBMED   14726512
REFERENCE   4  (bases 1 to 991)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   5  (bases 1 to 991)
  AUTHORS   Bauer,M.F., Rothbauer,U., Muhlenbein,N., Smith,R.J., Gerbitz,K.,
            Neupert,W., Brunner,M. and Hofmann,S.
  TITLE     The mitochondrial TIM22 preprotein translocase is highly conserved
            throughout the eukaryotic kingdom
  JOURNAL   FEBS Lett 464 (1-2), 41-47 (1999)
   PUBMED   10611480
REFERENCE   6  (bases 1 to 991)
  AUTHORS   Hadjiargyrou,M., Halsey,M.F., Ahrens,W., Rightmire,E.P.,
            McLeod,K.J. and Rubin,C.T.
  TITLE     Cloning of a novel cDNA expressed during the early stages of
            fracture healing
  JOURNAL   Biochem Biophys Res Commun 249 (3), 879-884 (1998)
   PUBMED   9731230
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ210619.1, SRR22399481.1504001.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-51                JAXUCZ010000001.1  169392355-169392405
            52-147              JAXUCZ010000001.1  169392548-169392643
            148-991             JAXUCZ010000001.1  169392813-169393656
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..991
                     /gene="Timm10b"
                     /gene_synonym="Fxc1; tim10b; Tim9b"
                     /note="translocase of inner mitochondrial membrane 10B"
                     /db_xref="GeneID:84384"
                     /db_xref="RGD:71097"
     exon            1..51
                     /gene="Timm10b"
                     /gene_synonym="Fxc1; tim10b; Tim9b"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..324
                     /gene="Timm10b"
                     /gene_synonym="Fxc1; tim10b; Tim9b"
                     /note="mitochondrial import inner membrane translocase
                     subunit Tim9 B; fracture callus protein 1; fracture callus
                     1; fractured callus expressed transcript 1; translocase of
                     inner mitochondrial membrane 10 homolog B"
                     /codon_start=1
                     /product="mitochondrial import inner membrane translocase
                     subunit Tim10 B"
                     /protein_id="NP_001376161.1"
                     /db_xref="GeneID:84384"
                     /db_xref="RGD:71097"
                     /translation="MEHQQQQLRNLRDFLLVYNRMTELCFQRCVPSLHHRALDAEEEA
                     CLHSCAGKLIHSNHRLMAAYVHLMPALVQRRMADYEAASAVPGVPAEQPRDSPSGS"
     exon            52..147
                     /gene="Timm10b"
                     /gene_synonym="Fxc1; tim10b; Tim9b"
                     /inference="alignment:Splign:2.1.0"
     exon            148..991
                     /gene="Timm10b"
                     /gene_synonym="Fxc1; tim10b; Tim9b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acgccatgcg ccctgggcgt gatggagcac cagcagcagc aactgagaaa cttgcgagac
       61 tttctgttgg tctacaatcg gatgacagaa ctgtgcttcc agcgctgtgt gcccagcctg
      121 caccaccgag ctctggacgc tgaggaggag gcctgcctgc acagctgtgc tgggaagctc
      181 atccattcta accaccgcct catggccgct tacgtgcacc tcatgcccgc cctggtccag
      241 cgccgcatgg cggactacga ggctgcctct gccgtgccag gtgttcctgc agaacagccc
      301 agagactcgc catcaggcag ctagctagct gtccctgacc gcaggagaga aggtgcttgg
      361 ataggctcct ctatggacct tgggcttgtc taaatatgta cagagagact gagcttgaaa
      421 gctgggtgct cttgctcctt ttcttggagc caataaaccc gtttttgtat tctggttaat
      481 ttacttggca agaacttttc tttattggta ccatccttta ttctgtcatc tactgcctgt
      541 ctagtgcctt tagccttggc agttgatgta ttaccttctt gtatgtagaa ggacaaattt
      601 agcattccca gcaccccagc aaaagcaagg attatggcta cagtttgaag gttggtaata
      661 acaatgggaa attggttcca aaaggagagt tctctgtgcc tgtcctaggg tctaactcaa
      721 gtacctgaat atacattggc tcttaactag tttttattct cagctgtcag acaaaagaat
      781 tgctgtagat ctaggggaag aaggtaatat caaacaacaa aagcaggaag aaaacagtgc
      841 ccccttaggt tttagtcact gcttcctagg agatcagtga caacagaaca aagacaagcc
      901 tctaagaatt taggaatgtt gaccatttcc ccaatttact ctcttagtat ttcctgcttt
      961 tgtgaaatta gaaataaaga ctttaaacaa a
//
