LOCUS       NM_001013193            1680 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Tia1 cytotoxic granule-associated RNA binding
            protein-like 1 (Tial1), mRNA.
ACCESSION   NM_001013193 XM_341937
VERSION     NM_001013193.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1680)
  AUTHORS   Guo,X., Sun,Y., Azad,T., Janse van Rensburg,H.J., Luo,J., Yang,S.,
            Liu,P., Lv,Z., Zhan,M., Lu,L., Zhou,Y., Ma,X., Zhang,X., Yang,X.
            and Xue,L.
  TITLE     Rox8 promotes microRNA-dependent yki messenger RNA decay
  JOURNAL   Proc Natl Acad Sci U S A 117 (48), 30520-30530 (2020)
   PUBMED   33203680
REFERENCE   2  (bases 1 to 1680)
  AUTHORS   Kornblihtt,A.R., Schor,I.E., Allo,M., Dujardin,G., Petrillo,E. and
            Munoz,M.J.
  TITLE     Alternative splicing: a pivotal step between eukaryotic
            transcription and translation
  JOURNAL   Nat Rev Mol Cell Biol 14 (3), 153-165 (2013)
   PUBMED   23385723
  REMARK    Review article
            Erratum:[Nat Rev Mol Cell Biol. 2013 Mar;14(3).
            doi:10.1038/nrm3560]
REFERENCE   3  (bases 1 to 1680)
  AUTHORS   Zou,T., Rao,J.N., Liu,L., Xiao,L., Cui,Y.H., Jiang,Z., Ouyang,M.,
            Donahue,J.M. and Wang,J.Y.
  TITLE     Polyamines inhibit the assembly of stress granules in normal
            intestinal epithelial cells regulating apoptosis
  JOURNAL   Am J Physiol Cell Physiol 303 (1), C102-C111 (2012)
   PUBMED   22555848
REFERENCE   4  (bases 1 to 1680)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 1680)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 1680)
  AUTHORS   Cok,S.J., Acton,S.J. and Morrison,A.R.
  TITLE     The proximal region of the 3'-untranslated region of
            cyclooxygenase-2 is recognized by a multimeric protein complex
            containing HuR, TIA-1, TIAR, and the heterogeneous nuclear
            ribonucleoprotein U
  JOURNAL   J Biol Chem 278 (38), 36157-36162 (2003)
   PUBMED   12855701
REFERENCE   7  (bases 1 to 1680)
  AUTHORS   Piecyk,M., Wax,S., Beck,A.R., Kedersha,N., Gupta,M., Maritim,B.,
            Chen,S., Gueydan,C., Kruys,V., Streuli,M. and Anderson,P.
  TITLE     TIA-1 is a translational silencer that selectively regulates the
            expression of TNF-alpha
  JOURNAL   EMBO J 19 (15), 4154-4163 (2000)
   PUBMED   10921895
REFERENCE   8  (bases 1 to 1680)
  AUTHORS   Jin,K., Li,W., Nagayama,T., He,X., Sinor,A.D., Chang,J., Mao,X.,
            Graham,S.H., Simon,R.P. and Greenberg,D.A.
  TITLE     Expression of the RNA-binding protein TIAR is increased in neurons
            after ischemic cerebral injury
  JOURNAL   J Neurosci Res 59 (6), 767-774 (2000)
   PUBMED   10700014
REFERENCE   9  (bases 1 to 1680)
  AUTHORS   Beck,A.R., Miller,I.J., Anderson,P. and Streuli,M.
  TITLE     RNA-binding protein TIAR is essential for primordial germ cell
            development
  JOURNAL   Proc Natl Acad Sci U S A 95 (5), 2331-2336 (1998)
   PUBMED   9482885
REFERENCE   10 (bases 1 to 1680)
  AUTHORS   Morino,P., Herrera-Marschitz,M., Meana,J.J., Ungerstedt,U. and
            Hokfelt,T.
  TITLE     Immunohistochemical evidence for a crossed cholecystokinin
            corticostriatal pathway in the rat
  JOURNAL   Neurosci Lett 148 (1-2), 133-136 (1992)
   PUBMED   1300485
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091409.1.
            
            On Apr 20, 2005 this sequence version replaced XM_341937.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091409.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1680
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q37"
     gene            1..1680
                     /gene="Tial1"
                     /note="Tia1 cytotoxic granule-associated RNA binding
                     protein-like 1"
                     /db_xref="GeneID:361655"
                     /db_xref="RGD:1595845"
     exon            1..240
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     CDS             209..1387
                     /gene="Tial1"
                     /note="RNA binding protein TIAR (TIA-1 related); Tial 1
                     cytotoxic granule-associated RNA- binding protein-like 1;
                     Tial1 cytotoxic granule-associated RNA binding
                     protein-like 1"
                     /codon_start=1
                     /product="nucleolysin TIAR"
                     /protein_id="NP_001013211.1"
                     /db_xref="GeneID:361655"
                     /db_xref="RGD:1595845"
                     /translation="MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQ
                     PDSRRVNSSVGFSVLQHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATT
                     PSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFV
                     SFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSS
                     PKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVS
                     VNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVP
                     PYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASFPTQ
                     "
     exon            241..337
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            338..487
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            488..542
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            543..630
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            631..706
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            707..815
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            816..911
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            912..996
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1120
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            1121..1260
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
     exon            1261..1658
                     /gene="Tial1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttttgttcat cctcctcctc ctcctgctcc tcctggttgg agcgcagtgt ccggagcggg
       61 ctggggggag cgagcccaag agccgggttc agtacctttt cctctgtccc cagccggcgc
      121 ccggagtccc cctccccttc cttcccgccc cctcccctcc ccagccctgc cctccccctt
      181 gtcccgggat cactccgtcg cacccaccat gatggaagac gacggacagc cccggactct
      241 atacgtaggt aacctctcca gagatgtgac agaagtcctt atccttcagt tattcagtca
      301 gatcggaccc tgtaaaagct gtaaaatgat aacagagcaa cccgatagca gaagggtcaa
      361 ctcttctgtt ggattttctg ttttgcagca tacaagcaat gacccatatt gctttgtgga
      421 attttatgaa cacagagatg cagctgctgc attagctgct atgaatggga gaaaaatttt
      481 gggaaaggag gtcaaagtaa actgggcaac aacaccaagt agccagaaaa aagacacttc
      541 caatcacttc catgtgtttg ttggggattt gagtccagaa attacaacag aagatatcaa
      601 gtcagcattt gccccctttg gtaaaatatc ggatgcccgg gtagttaaag atatggcaac
      661 tggaaagtcc aaaggctatg gttttgtatc tttttataac aaactggatg cagagaatgc
      721 aattgtgcat atggggggtc agtggttggg aggtcgacaa atcagaacca attgggccac
      781 acgtaaacca cctgccccta aaagtacaca agaaactaac actaagcagt tgagatttga
      841 agatgtagta aaccagtcaa gtccaaaaaa ctgcactgtg tactgtgggg ggatcgcttc
      901 ggggctgaca gatcaactta tgagacaaac attttcacca tttggacaaa ttatggagat
      961 aagagttttt ccagagaagg ggtattcgtt tgtcagattt tcaactcatg aaagtgcagc
     1021 ccatgctatt gtttctgtga acggtactac aatcgaagga catgtggtta aatgctattg
     1081 gggtaaagaa tctcctgata tgactaaaaa cttccaacag gttgactaca gtcagtgggg
     1141 ccaatggagc caagtgtatg gaaacccaca acagtacgga cagtatatgg caaatgggtg
     1201 gcaagtacct ccctatggag tatatgggca gccatggaac caacaaggat ttggagtaga
     1261 tcaatcacct tctgctgctt ggatgggtgg atttggtgct cagcctccac aaggacaagc
     1321 tccgccccct gtcatacctc ctccaaacca agctgggtat ggaatggcaa gtttcccaac
     1381 acagtgagtg agctgggact ctaaacacaa gtgtaaccca ccgcaggctg caggctcctg
     1441 tgacactctg aagacatgaa gagtaaacat cgggaatgaa aatatttatt ttaaaaattg
     1501 aaatgtttgg atcctttagc acagctttgc ttggtgaagg acacgtgtct tctagttctg
     1561 cctttttaag tttttttgtt catgatggat atgaacatga tttttctttg tgtacaaaaa
     1621 actaaaataa agtcaataaa gacaattctg actataaaaa aaaaaaaaaa aaaaaaaaaa
//
