LOCUS       XM_039107604            5567 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus TIA1 cytotoxic granule-associated RNA
            binding protein (Tia1), transcript variant X5, mRNA.
ACCESSION   XM_039107604
VERSION     XM_039107604.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5567
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5567
                     /gene="Tia1"
                     /note="TIA1 cytotoxic granule-associated RNA binding
                     protein; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 41 ESTs, 4 long SRA reads, 2
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 20 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312510"
                     /db_xref="RGD:1305742"
     CDS             1483..2448
                     /gene="Tia1"
                     /codon_start=1
                     /product="cytotoxic granule associated RNA binding protein
                     TIA1 isoform X4"
                     /protein_id="XP_038963532.1"
                     /db_xref="GeneID:312510"
                     /db_xref="RGD:1305742"
                     /translation="MNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVF
                     VGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM
                     GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPGNCTVYCGGVTSGL
                     TEQLMRQTFSPFGQIMEIRVFPDKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYW
                     GKETLDMINPVQQQNQIGYPPAYGQWGQWYGNAQQIGQYVPNGWQVPAYGMYGQPWSQ
                     QGFNQTQSSAPWMGPNYSVPPPQGQNGGMLPNQPAGYRVAGYETQ"
ORIGIN      
        1 ctgtgcgcat gcgcggcgcg ggtcactcgg ctgtcggctc ctaagcgtcc ggctcgccgc
       61 catcttggat cggggtttca ttgttcgcgg tgggacgggc atttttgtgt aatcgctgcc
      121 aaagaagaaa gcgaagtagc ctccagtcaa gcgaggaggc cggctcttcc gcagccatag
      181 ccacctcaac gatttgggag gtagcgaagg gcagggagct ggaccctgag gtgccgccgc
      241 gactgcagca gccatggagg acgagatgcc caagactcta tacgtcggta acctttctcg
      301 agatgtgaca gaagctctca tcctccagct ctttagccag atcggacctt gtaaaaactg
      361 caaaatgatt atggatgtaa gggtatttca ctcagtcact gttcttcctt ccttaacata
      421 ctaataaagg tgttgtaact gcagaacttc ttcattaatg tctattcata ggggtcggag
      481 tgaatttgta attaacctgt ttagtagaca accaagtttc ttttgctaag tgaatggcgt
      541 gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtgtgtgtgt gtaagttcta
      601 ttgaggtatc agaattgttt tacatgtagt gttaatcagc tgaatgacct ataagttcag
      661 ttattagatt gggaattgtg gtagacttac aatgaaaaaa tatataacaa acaatatttt
      721 tagcttcatt tttaaaggtt ttcttggatg tctgtcagac cttaacgttt agaaaactta
      781 atcatatggc tgatgttaac tgcgaataat atctagtttt tagaacaaag ttgattgtat
      841 gttagcaggt atgtggaggc cagacgtcaa cattggtggt tccttatgta tacgtagtag
      901 acagggtttt atactgtaat ccaggatgac taggaatgct gtataagctg tggtcttcct
      961 gacttagctt ctcagtgcta atattgcaat aggccaccac agcctggcaa tttatttatt
     1021 tttgagatgt ggtctatgaa tttaattcag actgtcctga aacttgaaat gttcttccgc
     1081 ttgagtgata gaatgataga tgtgctatcg ccccacagaa tctcagttat tctagaataa
     1141 gagagtgttg actgaatgtc atgcttatct ctacgctctg aaattgtgaa ttagtttcct
     1201 ttaataattc ttaaaaagcc ttagaatgaa ttacaagaat tataaagtca tttttgttct
     1261 gtactagtaa gtccagatta ttagattgtt ttctgcttta atttttcata aaatatcttg
     1321 aagccaggtg tcatagtata tgcctgtcat ctcagaactc agtagcaggg aacgggatca
     1381 ctgttggagg ccgctctaat ctacatacag acggcaggaa atgacccgta ctgtttcgtg
     1441 gagttccatg agcatcgcca cgcagctgca gccctggctg ctatgaatgg gcggaagata
     1501 atgggtaagg aagtgaaagt gaattgggca acaaccccta gcagtcaaaa gaaagataca
     1561 agcagtagta ccgttgtcag cacacagcgt tcacaagatc atttccatgt gtttgttggt
     1621 gacctcagtc cagaaatcac aactgaagac atcaaagcag cttttgcacc atttggaaga
     1681 atttcagatg cccgtgtggt aaaagacatg gctaccggga agtctaaggg atatggcttt
     1741 gtctcctttt tcaacaaatg ggatgcagaa aatgccattc agcagatggg tggccagtgg
     1801 cttggtggaa gacaaatcag aactaactgg gcaacccgaa agcctccagc tccaaagagt
     1861 acatatgagt caaacaccaa acagctgtca tacgatgagg ttgtgagtca gtctagtccc
     1921 ggcaactgta ccgtgtactg tggaggagtg acgtcaggac tgacagaaca actaatgcgt
     1981 cagacttttt ctccatttgg acaaataatg gaaatccgag tctttccaga taaagggtac
     2041 tcattcattc ggttcagttc ccatgaaagt gcggcacatg caattgtttc tgttaacggt
     2101 actaccattg aagggcatgt ggtgaaatgt tactggggca aagagactct tgacatgata
     2161 aaccccgtgc agcagcaaaa tcaaattgga tatccaccag catatggcca gtggggccag
     2221 tggtatggaa atgcacaaca gattggccag tatgtaccta atggttggca agtacctgcc
     2281 tatggaatgt atggccagcc atggagccag cagggattca atcagaccca gtcttctgca
     2341 ccatggatgg gacccaatta cagtgtgccg ccacctcaag ggcagaacgg cggcatgctg
     2401 cctaatcagc ctgctgggta tcgagtggca gggtatgaaa cccagtaaaa acagacgaca
     2461 gaatggaagc cagtggcttg aagccacagg gagggtagga aagccgatgt ttacttcaag
     2521 atttatcaaa tcagtcagta caaatgccag atacaatgta tttatttaaa agattcattt
     2581 ttaaaatcat gacattactt ttcatccaca ttgttttaaa aaggaacaag atggtggatg
     2641 tctgccaatt tttgcttcat tatctttttg ataaagtctc tcagatcctt gtttctcaga
     2701 caaatgcagg gcttgctgcc actttgttaa aataagaggc agagaattgc acaatggtga
     2761 attttttcca ctgaaatagt gtgcagttta agtttgcatt cctgatatga tataaaacat
     2821 gtaatataga tgtaaaaaaa aagtcaaact tgtgcaaggt ctagaagttc tttgtgactt
     2881 tcagcgcgtg cacagttgtc ttaggttaaa gggtaggcat tatgtgagct ataccatctc
     2941 cactattatc cctttggaat ttttaaatgt aaattattag tttatatcat tttgtatcca
     3001 cagttttttc acaaattgtc cggccttatg aaaaaatctg taaaatactc ttaaatgaaa
     3061 aaaatgatgt tcacttagat tgaaaacttt tctcagatgg actgataatt acattcatct
     3121 tgtttttata tgagaaggtg cctcaaggat tccctgttgg acttgtttaa aaggactttt
     3181 tatcttctgt gataaccttt gccatatacc aggaactagg aaaacaagga acttgttact
     3241 aaagagaatc tgcagtgata agtcctcacc cacatgagct tcgtgtgtca acgtctgtgt
     3301 ttacatgtat gtttctaaga tacttcagca agccacagtt tgcagttagc agactttgtc
     3361 tgtcatttcc ttcctacagg tgtcatgaag cggtgatgta cgacagattt tacacttgca
     3421 tgtgaatatc acatacatac tttgatagtc tttgatacaa actcatctgc tcttgttttt
     3481 caagaatttt gagacacaaa gttgtatgta tcagaatata ttaattagat attttagtta
     3541 gatttactta agaagtgaat ccactttgat atgtacagat ggtagctgtg aaactgtggc
     3601 tgtccctcta tcaggcttgg ggttcattaa gacctctaaa ctagcctgaa gggccagcca
     3661 ggcaagacag ttttaaatat tcacaggcca aaatagaaca aacaaataaa cccttaagtc
     3721 ctacctcctt aaacagcctt caaggaaatg ctcctgagca ctgtgtggct ttggtccttc
     3781 agtaccaggt cccctggagc tctcacatta ctatttttga ggtttgctct ctgttggcat
     3841 tgatctagcc ttagggtttc taatatattt cagagtctct tggtttggtg tggtttcagt
     3901 gatgaccaca accttctcct tgacaggaga gaggaaggag cccctgtgca ttgtgggttt
     3961 tgagacctgc ggagagctcc cagcatttta ctcaggcctg tggaactgga agcatttcct
     4021 ggcctgtatc tttcaggtag gagcacacaa ctctaacctg tgtctaagcc agtccccttg
     4081 tccaacagcc caggaagaca gtcccaatgt gtgcttctct ggagctcagt tctatgcagt
     4141 tgtgctaatg tttcattaag tcactgtgta tttttaagta ctaaaacatt gaaatttgct
     4201 ttatggaaga tgaataaatt ttttaaatac ttggaaattt tatttctttg taaacttctt
     4261 cagattagga caggcaataa aagcagctta aataaaatac taaaagcaaa aagattaaaa
     4321 actcacgcat gaggaagcta tttttagttt tttctggatt tgtctcttat tttagcatcc
     4381 tcagtatctc tgtttaagac tttttcttct tttgtaagtt taggctgcag gatcttttgg
     4441 gcataagtag tttattttgt gcaaaagtgt agtttcttct tttgactctg tcgaggacta
     4501 aggacgttta ttagtagcat attctttttt tttttttttt ttttggttct tttttttcgg
     4561 agctggggac tgaacccagg gccttgcgct tcctaggtaa gcactctacc actgagctaa
     4621 atccccagcc ccttagtagc atattcttat tgcatatcct acagtcacgt tgatttgctg
     4681 ttgggagggt agtggtgctg tgttcctgat gaaggactga catttcagga acatggctgt
     4741 tgttagttta aatgaatcat ttaaatcatt tctcaacctg aaaaacttca tcctggtata
     4801 agaatcaggc aaggaaatga aggtttttaa agtcaacttc cctgcaatat gcattcaggt
     4861 tttactctct ggtactgtga agaacctgag tggctcttgg tgggtcatgg agccagtatt
     4921 ctttatcctg actgtttgga tgttaaaatt cctctatgtt ttatatgacc agtggggtct
     4981 tcttgcagtg attattgtgt gtgagatccc ccacccaagt gttcatatta ctaactctca
     5041 ggttcacctt atcccagaag ccatggtctg cataggttcc agaggctctg cactctgcag
     5101 ccttagctaa ctgtgaagcc agagtttggt cttcctggtg aaaacgagac tcactgtcta
     5161 gcttatcctt ctcttgtttt acccctgtgc tcatcttcct tttagattcg tgctagagtt
     5221 ccatttcatt ttcagaggac tcgaatactc cacagaagga gtagacagac tcctaagggc
     5281 tatccatgct actgagatta tagtctactt agatcaacaa aatatattca taggaaaatt
     5341 gaaaaagcaa gacttttaaa tgagcggtga tttctaaaaa ttatttttta ttggtgtagt
     5401 gacctggttt atcaggtaaa ggtgactgcc atcaaccaag cctgatgacc tgagttgaac
     5461 acactcggtg gaagtagaga attaactctc tcaacaaact atcctcttcc ctccacatgt
     5521 gtgcacccta ccacggccac atatataaat aaatctttaa aactgtt
//
