LOCUS       XM_006236830            4503 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus TIA1 cytotoxic granule-associated RNA
            binding protein (Tia1), transcript variant X4, mRNA.
ACCESSION   XM_006236830
VERSION     XM_006236830.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006236830.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006236830.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4503
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4503
                     /gene="Tia1"
                     /note="TIA1 cytotoxic granule-associated RNA binding
                     protein; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 42 ESTs, 5 long SRA reads, 4
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 165 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312510"
                     /db_xref="RGD:1305742"
     CDS             254..1384
                     /gene="Tia1"
                     /codon_start=1
                     /product="cytotoxic granule associated RNA binding protein
                     TIA1 isoform X3"
                     /protein_id="XP_006236892.1"
                     /db_xref="GeneID:312510"
                     /db_xref="RGD:1305742"
                     /translation="MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDQTA
                     GNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGD
                     LSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQ
                     WLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPGNCTVYCGGVTSGLTEQ
                     LMRQTFSPFGQIMEIRVFPDKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKE
                     TLDMINPVQQQNQIGYPPAYGQWGQWYGNAQQIGQYVPNGWQVPAYGMYGQPWSQQGF
                     NQTQSSAPWMGPNYSVPPPQGQNGGMLPNQPAGYRVAGYETQ"
ORIGIN      
        1 ctgtgcgcat gcgcggcgcg ggtcactcgg ctgtcggctc ctaagcgtcc ggctcgccgc
       61 catcttggat cggggtttca ttgttcgcgg tgggacgggc atttttgtgt aatcgctgcc
      121 aaagaagaaa gcgaagtagc ctccagtcaa gcgaggaggc cggctcttcc gcagccatag
      181 ccacctcaac gatttgggag gtagcgaagg gcagggagct ggaccctgag gtgccgccgc
      241 gactgcagca gccatggagg acgagatgcc caagactcta tacgtcggta acctttctcg
      301 agatgtgaca gaagctctca tcctccagct ctttagccag atcggacctt gtaaaaactg
      361 caaaatgatt atggatcaga cggcaggaaa tgacccgtac tgtttcgtgg agttccatga
      421 gcatcgccac gcagctgcag ccctggctgc tatgaatggg cggaagataa tgggtaagga
      481 agtgaaagtg aattgggcaa caacccctag cagtcaaaag aaagatacaa gcaatcattt
      541 ccatgtgttt gttggtgacc tcagtccaga aatcacaact gaagacatca aagcagcttt
      601 tgcaccattt ggaagaattt cagatgcccg tgtggtaaaa gacatggcta ccgggaagtc
      661 taagggatat ggctttgtct cctttttcaa caaatgggat gcagaaaatg ccattcagca
      721 gatgggtggc cagtggcttg gtggaagaca aatcagaact aactgggcaa cccgaaagcc
      781 tccagctcca aagagtacat atgagtcaaa caccaaacag ctgtcatacg atgaggttgt
      841 gagtcagtct agtcccggca actgtaccgt gtactgtgga ggagtgacgt caggactgac
      901 agaacaacta atgcgtcaga ctttttctcc atttggacaa ataatggaaa tccgagtctt
      961 tccagataaa gggtactcat tcattcggtt cagttcccat gaaagtgcgg cacatgcaat
     1021 tgtttctgtt aacggtacta ccattgaagg gcatgtggtg aaatgttact ggggcaaaga
     1081 gactcttgac atgataaacc ccgtgcagca gcaaaatcaa attggatatc caccagcata
     1141 tggccagtgg ggccagtggt atggaaatgc acaacagatt ggccagtatg tacctaatgg
     1201 ttggcaagta cctgcctatg gaatgtatgg ccagccatgg agccagcagg gattcaatca
     1261 gacccagtct tctgcaccat ggatgggacc caattacagt gtgccgccac ctcaagggca
     1321 gaacggcggc atgctgccta atcagcctgc tgggtatcga gtggcagggt atgaaaccca
     1381 gtaaaaacag acgacagaat ggaagccagt ggcttgaagc cacagggagg gtaggaaagc
     1441 cgatgtttac ttcaagattt atcaaatcag tcagtacaaa tgccagatac aatgtattta
     1501 tttaaaagat tcatttttaa aatcatgaca ttacttttca tccacattgt tttaaaaagg
     1561 aacaagatgg tggatgtctg ccaatttttg cttcattatc tttttgataa agtctctcag
     1621 atccttgttt ctcagacaaa tgcagggctt gctgccactt tgttaaaata agaggcagag
     1681 aattgcacaa tggtgaattt tttccactga aatagtgtgc agtttaagtt tgcattcctg
     1741 atatgatata aaacatgtaa tatagatgta aaaaaaaagt caaacttgtg caaggtctag
     1801 aagttctttg tgactttcag cgcgtgcaca gttgtcttag gttaaagggt aggcattatg
     1861 tgagctatac catctccact attatccctt tggaattttt aaatgtaaat tattagttta
     1921 tatcattttg tatccacagt tttttcacaa attgtccggc cttatgaaaa aatctgtaaa
     1981 atactcttaa atgaaaaaaa tgatgttcac ttagattgaa aacttttctc agatggactg
     2041 ataattacat tcatcttgtt tttatatgag aaggtgcctc aaggattccc tgttggactt
     2101 gtttaaaagg actttttatc ttctgtgata acctttgcca tataccagga actaggaaaa
     2161 caaggaactt gttactaaag agaatctgca gtgataagtc ctcacccaca tgagcttcgt
     2221 gtgtcaacgt ctgtgtttac atgtatgttt ctaagatact tcagcaagcc acagtttgca
     2281 gttagcagac tttgtctgtc atttccttcc tacaggtgtc atgaagcggt gatgtacgac
     2341 agattttaca cttgcatgtg aatatcacat acatactttg atagtctttg atacaaactc
     2401 atctgctctt gtttttcaag aattttgaga cacaaagttg tatgtatcag aatatattaa
     2461 ttagatattt tagttagatt tacttaagaa gtgaatccac tttgatatgt acagatggta
     2521 gctgtgaaac tgtggctgtc cctctatcag gcttggggtt cattaagacc tctaaactag
     2581 cctgaagggc cagccaggca agacagtttt aaatattcac aggccaaaat agaacaaaca
     2641 aataaaccct taagtcctac ctccttaaac agccttcaag gaaatgctcc tgagcactgt
     2701 gtggctttgg tccttcagta ccaggtcccc tggagctctc acattactat ttttgaggtt
     2761 tgctctctgt tggcattgat ctagccttag ggtttctaat atatttcaga gtctcttggt
     2821 ttggtgtggt ttcagtgatg accacaacct tctccttgac aggagagagg aaggagcccc
     2881 tgtgcattgt gggttttgag acctgcggag agctcccagc attttactca ggcctgtgga
     2941 actggaagca tttcctggcc tgtatctttc aggtaggagc acacaactct aacctgtgtc
     3001 taagccagtc cccttgtcca acagcccagg aagacagtcc caatgtgtgc ttctctggag
     3061 ctcagttcta tgcagttgtg ctaatgtttc attaagtcac tgtgtatttt taagtactaa
     3121 aacattgaaa tttgctttat ggaagatgaa taaatttttt aaatacttgg aaattttatt
     3181 tctttgtaaa cttcttcaga ttaggacagg caataaaagc agcttaaata aaatactaaa
     3241 agcaaaaaga ttaaaaactc acgcatgagg aagctatttt tagttttttc tggatttgtc
     3301 tcttatttta gcatcctcag tatctctgtt taagactttt tcttcttttg taagtttagg
     3361 ctgcaggatc ttttgggcat aagtagttta ttttgtgcaa aagtgtagtt tcttcttttg
     3421 actctgtcga ggactaagga cgtttattag tagcatattc tttttttttt tttttttttt
     3481 ggttcttttt tttcggagct ggggactgaa cccagggcct tgcgcttcct aggtaagcac
     3541 tctaccactg agctaaatcc ccagcccctt agtagcatat tcttattgca tatcctacag
     3601 tcacgttgat ttgctgttgg gagggtagtg gtgctgtgtt cctgatgaag gactgacatt
     3661 tcaggaacat ggctgttgtt agtttaaatg aatcatttaa atcatttctc aacctgaaaa
     3721 acttcatcct ggtataagaa tcaggcaagg aaatgaaggt ttttaaagtc aacttccctg
     3781 caatatgcat tcaggtttta ctctctggta ctgtgaagaa cctgagtggc tcttggtggg
     3841 tcatggagcc agtattcttt atcctgactg tttggatgtt aaaattcctc tatgttttat
     3901 atgaccagtg gggtcttctt gcagtgatta ttgtgtgtga gatcccccac ccaagtgttc
     3961 atattactaa ctctcaggtt caccttatcc cagaagccat ggtctgcata ggttccagag
     4021 gctctgcact ctgcagcctt agctaactgt gaagccagag tttggtcttc ctggtgaaaa
     4081 cgagactcac tgtctagctt atccttctct tgttttaccc ctgtgctcat cttcctttta
     4141 gattcgtgct agagttccat ttcattttca gaggactcga atactccaca gaaggagtag
     4201 acagactcct aagggctatc catgctactg agattatagt ctacttagat caacaaaata
     4261 tattcatagg aaaattgaaa aagcaagact tttaaatgag cggtgatttc taaaaattat
     4321 tttttattgg tgtagtgacc tggtttatca ggtaaaggtg actgccatca accaagcctg
     4381 atgacctgag ttgaacacac tcggtggaag tagagaatta actctctcaa caaactatcc
     4441 tcttccctcc acatgtgtgc accctaccac ggccacatat ataaataaat ctttaaaact
     4501 gtt
//
