LOCUS       XM_006236828            4536 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus TIA1 cytotoxic granule-associated RNA
            binding protein (Tia1), transcript variant X1, mRNA.
ACCESSION   XM_006236828
VERSION     XM_006236828.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006236828.4.
            
            On Jan 21, 2021 this sequence version replaced XM_006236828.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4536
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4536
                     /gene="Tia1"
                     /note="TIA1 cytotoxic granule-associated RNA binding
                     protein; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 44 ESTs, 5 long SRA reads, 2
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 168 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:312510"
                     /db_xref="RGD:1305742"
     CDS             254..1417
                     /gene="Tia1"
                     /codon_start=1
                     /product="cytotoxic granule associated RNA binding protein
                     TIA1 isoform X1"
                     /protein_id="XP_006236890.1"
                     /db_xref="GeneID:312510"
                     /db_xref="RGD:1305742"
                     /translation="MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDQTA
                     GNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQR
                     SQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWD
                     AENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPGNCTVY
                     CGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFIRFSSHESAAHAIVSVNGTTIE
                     GHVVKCYWGKETLDMINPVQQQNQIGYPPAYGQWGQWYGNAQQIGQYVPNGWQVPAYG
                     MYGQPWSQQGFNQTQSSAPWMGPNYSVPPPQGQNGGMLPNQPAGYRVAGYETQ"
ORIGIN      
        1 ctgtgcgcat gcgcggcgcg ggtcactcgg ctgtcggctc ctaagcgtcc ggctcgccgc
       61 catcttggat cggggtttca ttgttcgcgg tgggacgggc atttttgtgt aatcgctgcc
      121 aaagaagaaa gcgaagtagc ctccagtcaa gcgaggaggc cggctcttcc gcagccatag
      181 ccacctcaac gatttgggag gtagcgaagg gcagggagct ggaccctgag gtgccgccgc
      241 gactgcagca gccatggagg acgagatgcc caagactcta tacgtcggta acctttctcg
      301 agatgtgaca gaagctctca tcctccagct ctttagccag atcggacctt gtaaaaactg
      361 caaaatgatt atggatcaga cggcaggaaa tgacccgtac tgtttcgtgg agttccatga
      421 gcatcgccac gcagctgcag ccctggctgc tatgaatggg cggaagataa tgggtaagga
      481 agtgaaagtg aattgggcaa caacccctag cagtcaaaag aaagatacaa gcagtagtac
      541 cgttgtcagc acacagcgtt cacaagatca tttccatgtg tttgttggtg acctcagtcc
      601 agaaatcaca actgaagaca tcaaagcagc ttttgcacca tttggaagaa tttcagatgc
      661 ccgtgtggta aaagacatgg ctaccgggaa gtctaaggga tatggctttg tctccttttt
      721 caacaaatgg gatgcagaaa atgccattca gcagatgggt ggccagtggc ttggtggaag
      781 acaaatcaga actaactggg caacccgaaa gcctccagct ccaaagagta catatgagtc
      841 aaacaccaaa cagctgtcat acgatgaggt tgtgagtcag tctagtcccg gcaactgtac
      901 cgtgtactgt ggaggagtga cgtcaggact gacagaacaa ctaatgcgtc agactttttc
      961 tccatttgga caaataatgg aaatccgagt ctttccagat aaagggtact cattcattcg
     1021 gttcagttcc catgaaagtg cggcacatgc aattgtttct gttaacggta ctaccattga
     1081 agggcatgtg gtgaaatgtt actggggcaa agagactctt gacatgataa accccgtgca
     1141 gcagcaaaat caaattggat atccaccagc atatggccag tggggccagt ggtatggaaa
     1201 tgcacaacag attggccagt atgtacctaa tggttggcaa gtacctgcct atggaatgta
     1261 tggccagcca tggagccagc agggattcaa tcagacccag tcttctgcac catggatggg
     1321 acccaattac agtgtgccgc cacctcaagg gcagaacggc ggcatgctgc ctaatcagcc
     1381 tgctgggtat cgagtggcag ggtatgaaac ccagtaaaaa cagacgacag aatggaagcc
     1441 agtggcttga agccacaggg agggtaggaa agccgatgtt tacttcaaga tttatcaaat
     1501 cagtcagtac aaatgccaga tacaatgtat ttatttaaaa gattcatttt taaaatcatg
     1561 acattacttt tcatccacat tgttttaaaa aggaacaaga tggtggatgt ctgccaattt
     1621 ttgcttcatt atctttttga taaagtctct cagatccttg tttctcagac aaatgcaggg
     1681 cttgctgcca ctttgttaaa ataagaggca gagaattgca caatggtgaa ttttttccac
     1741 tgaaatagtg tgcagtttaa gtttgcattc ctgatatgat ataaaacatg taatatagat
     1801 gtaaaaaaaa agtcaaactt gtgcaaggtc tagaagttct ttgtgacttt cagcgcgtgc
     1861 acagttgtct taggttaaag ggtaggcatt atgtgagcta taccatctcc actattatcc
     1921 ctttggaatt tttaaatgta aattattagt ttatatcatt ttgtatccac agttttttca
     1981 caaattgtcc ggccttatga aaaaatctgt aaaatactct taaatgaaaa aaatgatgtt
     2041 cacttagatt gaaaactttt ctcagatgga ctgataatta cattcatctt gtttttatat
     2101 gagaaggtgc ctcaaggatt ccctgttgga cttgtttaaa aggacttttt atcttctgtg
     2161 ataacctttg ccatatacca ggaactagga aaacaaggaa cttgttacta aagagaatct
     2221 gcagtgataa gtcctcaccc acatgagctt cgtgtgtcaa cgtctgtgtt tacatgtatg
     2281 tttctaagat acttcagcaa gccacagttt gcagttagca gactttgtct gtcatttcct
     2341 tcctacaggt gtcatgaagc ggtgatgtac gacagatttt acacttgcat gtgaatatca
     2401 catacatact ttgatagtct ttgatacaaa ctcatctgct cttgtttttc aagaattttg
     2461 agacacaaag ttgtatgtat cagaatatat taattagata ttttagttag atttacttaa
     2521 gaagtgaatc cactttgata tgtacagatg gtagctgtga aactgtggct gtccctctat
     2581 caggcttggg gttcattaag acctctaaac tagcctgaag ggccagccag gcaagacagt
     2641 tttaaatatt cacaggccaa aatagaacaa acaaataaac ccttaagtcc tacctcctta
     2701 aacagccttc aaggaaatgc tcctgagcac tgtgtggctt tggtccttca gtaccaggtc
     2761 ccctggagct ctcacattac tatttttgag gtttgctctc tgttggcatt gatctagcct
     2821 tagggtttct aatatatttc agagtctctt ggtttggtgt ggtttcagtg atgaccacaa
     2881 ccttctcctt gacaggagag aggaaggagc ccctgtgcat tgtgggtttt gagacctgcg
     2941 gagagctccc agcattttac tcaggcctgt ggaactggaa gcatttcctg gcctgtatct
     3001 ttcaggtagg agcacacaac tctaacctgt gtctaagcca gtccccttgt ccaacagccc
     3061 aggaagacag tcccaatgtg tgcttctctg gagctcagtt ctatgcagtt gtgctaatgt
     3121 ttcattaagt cactgtgtat ttttaagtac taaaacattg aaatttgctt tatggaagat
     3181 gaataaattt tttaaatact tggaaatttt atttctttgt aaacttcttc agattaggac
     3241 aggcaataaa agcagcttaa ataaaatact aaaagcaaaa agattaaaaa ctcacgcatg
     3301 aggaagctat ttttagtttt ttctggattt gtctcttatt ttagcatcct cagtatctct
     3361 gtttaagact ttttcttctt ttgtaagttt aggctgcagg atcttttggg cataagtagt
     3421 ttattttgtg caaaagtgta gtttcttctt ttgactctgt cgaggactaa ggacgtttat
     3481 tagtagcata ttcttttttt tttttttttt tttggttctt ttttttcgga gctggggact
     3541 gaacccaggg ccttgcgctt cctaggtaag cactctacca ctgagctaaa tccccagccc
     3601 cttagtagca tattcttatt gcatatccta cagtcacgtt gatttgctgt tgggagggta
     3661 gtggtgctgt gttcctgatg aaggactgac atttcaggaa catggctgtt gttagtttaa
     3721 atgaatcatt taaatcattt ctcaacctga aaaacttcat cctggtataa gaatcaggca
     3781 aggaaatgaa ggtttttaaa gtcaacttcc ctgcaatatg cattcaggtt ttactctctg
     3841 gtactgtgaa gaacctgagt ggctcttggt gggtcatgga gccagtattc tttatcctga
     3901 ctgtttggat gttaaaattc ctctatgttt tatatgacca gtggggtctt cttgcagtga
     3961 ttattgtgtg tgagatcccc cacccaagtg ttcatattac taactctcag gttcacctta
     4021 tcccagaagc catggtctgc ataggttcca gaggctctgc actctgcagc cttagctaac
     4081 tgtgaagcca gagtttggtc ttcctggtga aaacgagact cactgtctag cttatccttc
     4141 tcttgtttta cccctgtgct catcttcctt ttagattcgt gctagagttc catttcattt
     4201 tcagaggact cgaatactcc acagaaggag tagacagact cctaagggct atccatgcta
     4261 ctgagattat agtctactta gatcaacaaa atatattcat aggaaaattg aaaaagcaag
     4321 acttttaaat gagcggtgat ttctaaaaat tattttttat tggtgtagtg acctggttta
     4381 tcaggtaaag gtgactgcca tcaaccaagc ctgatgacct gagttgaaca cactcggtgg
     4441 aagtagagaa ttaactctct caacaaacta tcctcttccc tccacatgtg tgcaccctac
     4501 cacggccaca tatataaata aatctttaaa actgtt
//
