LOCUS       NM_001170548            1980 bp    mRNA    linear   ROD 18-JUN-2023
DEFINITION  Rattus norvegicus THUMP domain containing 3 (Thumpd3), transcript
            variant 3, mRNA.
ACCESSION   NM_001170548
VERSION     NM_001170548.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM120112.1 and BC166466.1.
            
            Transcript Variant: This variant (3) differs at the 5' end compared
            to variant 1. Variants 1-3 encoded the same protein.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC166466.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMD00132261, SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-570               FM120112.1         1-570
            571-1980            BC166466.1         539-1948
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1980
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /note="THUMP domain containing 3"
                     /db_xref="GeneID:500288"
                     /db_xref="RGD:1560852"
     exon            1..36
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     exon            37..323
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1583
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /EC_number="2.1.1.256"
                     /note="THUMP domain-containing protein 3"
                     /codon_start=1
                     /product="tRNA (guanine(6)-N2)-methyltransferase THUMP3"
                     /protein_id="NP_001164019.1"
                     /db_xref="GeneID:500288"
                     /db_xref="RGD:1560852"
                     /translation="MSDTQEATREHLDMNLHENKKPVPLIESGIRSESEHLQVTIGAT
                     VPTGFEQTAADEVREKLKSSCRISKDRGKIYFDIAVESLAQVHCLRSVDNLFVVVEEF
                     KDYQFKATKEEVLRDFEELAGKLPWSDPLKVWQINTTFKKKKAKRRKANQSAGREKAD
                     CGQGDNAGEKDGKKKLASGAADPHILDYYENPAIKEEISTLIGEVLASGEDENGQSLR
                     EEAEPQVQKFRVTCNRAGEKHCFTSNEAARGFGGAVQEYFKWKADMTNFDVEVLLNIH
                     NNEVIVAIALTEESLHRRNITHFGPTTLRSTLAYGMLRLCEPKPTDVIVDPMCGTGAI
                     PIEGATEWSHCYHIAGDNNPLAVNRAANNISSLLTKSQIKDGKTSWGLPIDAVQWDIC
                     NLPLRTASVDIIVTDMPFGKRMGSKKRNWNLYPACLREMSRVCRPRTGRAVLLTQDKK
                     CFTKALSGMGHVWRKVHTVWVNIGGLHAAVYLLKRTPQDFVHPSDQDGGKDPPW"
     exon            324..401
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     exon            402..878
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     exon            879..1009
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1079
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1195
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1306
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..1430
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1960
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1930..1935
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
     polyA_site      1960
                     /gene="Thumpd3"
                     /gene_synonym="RGD1560852"
ORIGIN      
        1 ttccggcggc gtgccctgag cgcgctgaac ccgcagaaac cgttagacct tttagaaaca
       61 tttccatcat gtctgacact caagaagcta ccagagaaca cttggatatg aaccttcatg
      121 agaacaagaa gccggtgccc ttgatagaaa gtggcatcag aagtgagtct gagcatctcc
      181 aagtcaccat tggagccact gtacctactg ggtttgagca aacagctgca gatgaagtga
      241 gagagaaatt gaagtcatcc tgcagaatca gcaaagaccg gggcaagata tattttgata
      301 ttgcagtgga aagtctggct caggttcatt gtctgagatc agtggataac ttgtttgtgg
      361 ttgttgagga gtttaaagat taccagttca aagctacaaa ggaagaagtt ctaagagact
      421 ttgaagaact ggctggaaaa ctcccatggt cggacccttt aaaagtctgg caaattaaca
      481 ccactttcaa gaagaagaag gcaaagcgca gaaaggccaa tcagagtgca ggcagagaga
      541 aggccgactg tggacagggc gacaatgccg gtgagaagga cggtaagaag aagcttgcca
      601 gtggtgcggc agatccacat atcttagact actatgaaaa tccagccatc aaagaagaga
      661 tatcaacctt aataggggaa gtcttggcat ctggcgaaga tgaaaacggt caaagcttaa
      721 gagaagaagc tgaaccgcaa gtgcagaagt tcagagtcac ctgcaacaga gcaggagaga
      781 agcattgctt tacatccaac gaggctgcca gaggttttgg aggtgctgtt caagagtact
      841 ttaagtggaa ggctgatatg accaactttg acgtagaggt tctcctgaac atccacaata
      901 atgaagtcat tgttgctatt gcactgacag aggagagtct ccatcgcaga aatattacac
      961 attttggacc tacaactctt aggtcaactc ttgcctatgg gatgctcagg ctctgtgaac
     1021 ctaaacctac tgatgtaatt gtagatccaa tgtgtggaac aggggcaata ccaatagagg
     1081 gggctactga gtggtctcac tgttaccata ttgctgggga caacaaccca ctggcagtga
     1141 acagagcagc aaataacatc tcatctctat tgactaagag ccagattaaa gatggaaaaa
     1201 catcctgggg tttgcccatt gatgctgttc agtgggatat ctgcaacctc cctctgcgaa
     1261 ctgcttctgt ggatattatt gtaacagaca tgccatttgg aaaaaggatg ggctccaaaa
     1321 agagaaattg gaatctctat ccagcttgcc ttcgggaaat gagccgtgtc tgtagaccaa
     1381 ggacaggtag agctgtactg cttactcagg acaagaaatg ttttaccaag gcattatctg
     1441 gaatgggaca tgtgtggcga aaggtccata cagtctgggt gaacatcggg ggccttcatg
     1501 ctgcagttta tcttctaaaa cgcactcctc aagactttgt tcatccttca gatcaagatg
     1561 gaggaaaaga ccctccttgg taaagcaaag aatgaagaca atttagcagt acttaacagt
     1621 tcctaacact ggaaacgtca gcataaagaa cttgctttgg gagaaaaata acagaaaagt
     1681 aaccaagtat tacagcttcc actgctgaac tactgtagaa tgcattagtg ttagcaaggt
     1741 gattgtaatg gtatttcttg agaagcctac actgcttggt ttctaagttt cagaacactt
     1801 taggccatat tctattgctt gtgcagccta ctgttcttgg tctaaagttt tttcacttta
     1861 catggatcat ctcaaatatc tcagaaactg gagcatccct gaagacctac agtttatcat
     1921 ctaccttaaa ataaatacat tacaacctga agaggacaaa aaaaaaaaaa aaaaaaaaaa
//
