LOCUS       NM_001191970            4938 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus thrombospondin type 1 domain containing 7A
            (Thsd7a), mRNA.
ACCESSION   NM_001191970 XM_575387
VERSION     NM_001191970.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4938)
  AUTHORS   Aktepe,O.H., Sahin,T.K., Guner,G., Guven,D.C., Yeter,H.H.,
            Kurtulan,O., Ozercan,I.H., Dizdar,O. and Yalcin,S.
  TITLE     Correlation Between THSD7A Expression and Tumor Characteristics of
            Azoxymethane-Induced Colon Cancer Model in Rats
  JOURNAL   Turk J Gastroenterol 32 (12), 1049-1056 (2021)
   PUBMED   34876395
  REMARK    GeneRIF: Correlation Between THSD7A Expression and Tumor
            Characteristics of Azoxymethane-Induced Colon Cancer Model in Rats.
REFERENCE   2  (bases 1 to 4938)
  AUTHORS   Tomas,N.M., Hoxha,E., Reinicke,A.T., Fester,L., Helmchen,U.,
            Gerth,J., Bachmann,F., Budde,K., Koch-Nolte,F., Zahner,G., Rune,G.,
            Lambeau,G., Meyer-Schwesinger,C. and Stahl,R.A.
  TITLE     Autoantibodies against thrombospondin type 1 domain-containing 7A
            induce membranous nephropathy
  JOURNAL   J Clin Invest 126 (7), 2519-2532 (2016)
   PUBMED   27214550
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from JAXUCZ010000004.1.
            
            On Feb 3, 2021 this sequence version replaced NM_001191970.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               JAXUCZ010000004.1  41865368-41865524   c
            158-989             JAXUCZ010000004.1  41685319-41686150   c
            990-1238            JAXUCZ010000004.1  41635476-41635724   c
            1239-1420           JAXUCZ010000004.1  41632764-41632945   c
            1421-1576           JAXUCZ010000004.1  41603649-41603804   c
            1577-1789           JAXUCZ010000004.1  41600875-41601087   c
            1790-1984           JAXUCZ010000004.1  41521980-41522174   c
            1985-2219           JAXUCZ010000004.1  41512484-41512718   c
            2220-2335           JAXUCZ010000004.1  41508779-41508894   c
            2336-2468           JAXUCZ010000004.1  41501296-41501428   c
            2469-2572           JAXUCZ010000004.1  41500064-41500167   c
            2573-2767           JAXUCZ010000004.1  41486222-41486416   c
            2768-3031           JAXUCZ010000004.1  41484675-41484938   c
            3032-3210           JAXUCZ010000004.1  41468412-41468590   c
            3211-3216           JAXUCZ010000004.1  41466153-41466158   c
            3217-3350           JAXUCZ010000004.1  41464615-41464748   c
            3351-3504           JAXUCZ010000004.1  41460104-41460257   c
            3505-3649           JAXUCZ010000004.1  41456542-41456686   c
            3650-3765           JAXUCZ010000004.1  41455201-41455316   c
            3766-3883           JAXUCZ010000004.1  41445635-41445752   c
            3884-4029           JAXUCZ010000004.1  41445253-41445398   c
            4030-4204           JAXUCZ010000004.1  41444677-41444851   c
            4205-4378           JAXUCZ010000004.1  41442340-41442513   c
            4379-4474           JAXUCZ010000004.1  41434710-41434805   c
            4475-4557           JAXUCZ010000004.1  41431922-41432004   c
            4558-4765           JAXUCZ010000004.1  41430470-41430677   c
            4766-4852           JAXUCZ010000004.1  41428048-41428134   c
            4853-4937           JAXUCZ010000004.1  41427276-41427360   c
FEATURES             Location/Qualifiers
     source          1..4938
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q21"
     gene            1..4938
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /note="thrombospondin type 1 domain containing 7A"
                     /db_xref="GeneID:500032"
                     /db_xref="RGD:1566201"
     CDS             1..4938
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /note="thrombospondin type-1 domain-containing protein 7A;
                     thrombospondin, type I, domain containing 7A"
                     /codon_start=1
                     /product="thrombospondin type-1 domain-containing protein
                     7A precursor"
                     /protein_id="NP_001178899.2"
                     /db_xref="GeneID:500032"
                     /db_xref="RGD:1566201"
                     /translation="MGLRAGRLASLSRGVLQLMRLPLLLLLLLSSGARGAAAQGDTEV
                     PTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHSEGWTTLHTNCKQAVRPSNQQNCFK
                     VCDWHKELYDWRLGPWNQCQPVISKSLEKARECVKGEEGIQVREITCIQKDKDIPAED
                     IICEYFEPKPLLEQACLIPCQQDCIVSEFSSWSECSRTCGSGLQHRTRHVVAPPQFGG
                     SGCPNLTEFQVCQSNPCEAEESMYSLQVGPWSACSVPHSRQARQARRRGKNKEREKER
                     GKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVMCLNRTGKSADLSFCQQ
                     ERLPMTFQSCVITKECQVSEWSEWSPCSKTCHDVTSPTGTRVRTRTIRQFPIGSEKEC
                     PELEEKEPCLSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGVQT
                     REIYCIQTNDILLSHINTQKDKEASKPVDSKLCTGPVPNTTQLCHVPCPIECEVSPWS
                     AWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWK
                     SVRLGDCEPDNGKACGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDC
                     VLSAWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGIRCPNSSALQEVRSCNEHP
                     CTVYHWQTGPWGQCIEDTSVSSFNTTTTWTGETSCSVGMQTRKVICVRVNVGQVGPKK
                     CPESLRPETVRPCLLPCRKDCIMTPYSDWTPCPSSCREGDSGARKQSRQRVIIQLPAY
                     GGRECSDPLYEEKACEAPPTCHSYRWKTHKWRRCQLVPWSIQQDVPGAQEGCGPGRQA
                     RAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAV
                     RTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLL
                     GVKVQGDNKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEW
                     SNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIW
                     VTEPWSVCKVTFVDMRDNCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRE
                     CKLPCPEDCVISEWGPWTQCSLPCNPSGSRQRSADPIRQPADEGRACPDAVEKEPCNL
                     NKNCYRYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNW
                     QMNSSCTVECPLNCQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMEQ
                     SKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSDGSADDFSKAVDEEFCA
                     NIELIIDGNKQIVLEETCTQPCPGDCYLNDWSSWSLCQLTCVNGEDLGFGGIQVRSRA
                     VIIQELENQHLCPEQILETKSCDDGQCYEYKWMASAWKGSSRTVWCQRSDGVNVTGGC
                     LVVSQPDADRSCNPPCSQPHSYCSEMKACRCEEGYTEVMSSNSTLEQCTLIPVVVIPT
                     VEDKRDVKTSRAVHPTQPSSNPAGRGRTWFLQPFGPDGRLKTWVYGVAAGAFVLLVFI
                     VSMIYLACKKPKKPQRRQNNRLKPLTLAYDGDADM"
     exon            1..157
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            158..989
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1238
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            1239..1420
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            1421..1576
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1789
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            1790..1984
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2219
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            2220..2335
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            2336..2468
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            2469..2572
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            2573..2767
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            2768..3031
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            3032..3210
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            3211..3216
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            3217..3350
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            3351..3504
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            3505..3649
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            3650..3765
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            3766..3883
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            3884..4029
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            4030..4204
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            4205..4378
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            4379..4474
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            4475..4557
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            4558..4765
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            4766..4853
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
     exon            4854..4938
                     /gene="Thsd7a"
                     /gene_synonym="RGD1566201"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggggctgc gagccgggcg cctggcgtcc ctgagccggg gcgtcctgca gctgatgcgg
       61 ctgccactgc tcctgctact cctgctgagc tctggagccc gcggggctgc ggcgcaggga
      121 gacacagagg tgcccaccct ctatctgtgg aagacgggtc cctggggacg gtgtatggga
      181 gatgactgtg gaccgggcgg catccagact cgggctgtgt ggtgcgctca ttcggaaggc
      241 tggacaacgt tacatacgaa ctgcaagcag gctgtgagac ccagtaacca gcaaaactgc
      301 ttcaaagtgt gtgactggca caaagagttg tacgactgga ggctgggacc ctggaatcag
      361 tgtcagcctg tgatttcaaa aagcctcgag aaagcacgag aatgtgtgaa gggggaggaa
      421 ggcatccagg tgagagagat aacgtgcatc cagaaggaca aggacattcc cgcagaggac
      481 atcatctgcg agtactttga acccaagccc ctcctggaac aggcctgcct catcccttgt
      541 cagcaagact gcatcgtgtc tgagttctcg tcctggtctg agtgctccag gacctgtggc
      601 agcggcctgc agcaccgcac taggcacgtg gtcgcaccac cacagtttgg aggctctggc
      661 tgtcccaacc tcactgagtt ccaggtatgc cagtccaacc cctgtgaggc agaggagagt
      721 atgtatagct tgcaggtagg gccctggagc gcatgctcag taccacactc acgtcaagcc
      781 aggcaagcca ggcgtcgtgg caaaaacaag gagagagaga aggagagagg aaaagctgtg
      841 aaggatccag aggcccgtga gctcatcaag aagaagagaa acagaaacag acaaaacaga
      901 caggagaaca gatactggga catccagatt gggtaccaga ccagggacgt gatgtgctta
      961 aacaggactg ggaagtctgc ggacctcagc ttttgccaac aagagagact gcccatgacc
     1021 ttccagtcct gtgtgatcac caaagagtgc caggtgtctg agtggtcgga gtggagcccg
     1081 tgttcaaaaa catgccacga tgtcacatct cctacaggca ctcgagtaag gacaaggacc
     1141 atcaggcagt ttccaattgg aagtgagaag gaatgtccgg aacttgagga gaaagagccc
     1201 tgtttgtctc aaggagatgg agctgtcctc tgtgctacgt atggctggag aactacagaa
     1261 tggacagagt gccacgtgga ccctttgctt agtcagcagg acaagaggcg tgccaaccag
     1321 acagccctct gtgggggtgg tgtccagacc cgggaaatat actgcataca gaccaacgac
     1381 atcttgctct cccatataaa tacacagaag gacaaagaag cttcaaaacc agtggactca
     1441 aaattatgca ctggtcctgt tcctaacacc acacagttgt gccacgttcc ttgtccaatt
     1501 gaatgtgagg tttcaccttg gtctgcctgg ggaccatgta cttatgaaaa ttgtaatgac
     1561 cagcaaggca aaaaaggatt caaattaagg aagcggcgca ttactaatga gcctactgga
     1621 ggttctgggg caactggaaa ctgccctcac ttattggaag ccattccctg tgaagagcca
     1681 tcctgctatg actggaaatc ggtgagactc ggagactgtg aaccagataa tggaaaagcc
     1741 tgtgggcccg gcactcaagt tcaagaggtt gtatgcatca acagtgatgg agaagaagtg
     1801 gacagacagc tatgccgaga tgcaatcttt cctatccctg tggcctgtga tgccccatgc
     1861 ccgaaggact gtgtgctcag tgcatggtcc acgtggtcct cctgttcaca cacctgctct
     1921 gggaaaacca cagaaggaaa acagatccga gctcggtcca ttctggccta tgcaggagaa
     1981 gaaggtggaa ttcgctgccc taacagcagt gctttgcaag aggtgcgcag ctgcaatgag
     2041 catccttgca ctgtgtacca ctggcaaact ggtccctggg gtcagtgtat agaggacaca
     2101 tcagtgtcat ccttcaatac aaccacaaca tggactgggg agacgtcatg ttctgtgggc
     2161 atgcagaccc ggaaagtcat ctgcgtgcga gtcaacgtgg gccaagtggg acccaagaag
     2221 tgtcctgaaa gccttcggcc tgaaacagtg agaccttgct tgcttccttg taggaaggat
     2281 tgtattatga ccccatacag tgactggaca ccatgtccct cttcatgcag agaaggggac
     2341 tctggagcca ggaagcagtc tcgacagcgc gtcatcattc agctgccagc ctatggaggc
     2401 agggaatgct cagacccact ctatgaagaa aaggcctgcg aggcccctcc cacatgtcac
     2461 agctacaggt ggaagacaca caaatggcgc cggtgccagt tagtcccttg gagcattcaa
     2521 caggatgtcc ctggagcaca ggaaggctgc gggcctggac ggcaggcaag agccattact
     2581 tgtcgaaagc aagatggagg gcaggctagc atccaggagt gcctccagta tgcaggccct
     2641 gtgccagccc tgacccaggc ttgccagatc ccctgccaag atgactgtca atttaccagc
     2701 tggtccaagt tttcttcatg caacggagac tgcggtgcag ttaggaccag aaagcgtgct
     2761 attgttggaa aaagtaaaaa gaaagaaaaa tgtaaaaact cccatctgta ccctctgatc
     2821 gagacccagt attgtccttg tgacaaatac aatgcacagc cagtggggaa ctggtcagac
     2881 tgcattttgc cggaagggaa ggctgaggtg ttgttgggag tgaaggtaca aggcgacaac
     2941 aaggaatgtg gacaaggata ccgttaccag gcgatggcgt gctacgatca aaatggcaga
     3001 cttgttgaaa catcgcgatg caacagccat ggttacatag aagaagcctg catcatcccc
     3061 tgcccctccg actgcaagct cagtgaatgg tctaactggt cccgctgcag taagtcctgt
     3121 ggcagcggtg tgaaggtccg gtccaagtgg ctgcgggaaa agccttataa cggaggaagg
     3181 ccttgcccca aactagacca tgtcaaccag gcgcaggtgt atgaggtcgt cccgtgccac
     3241 agtgactgca accagtacat atgggtcaca gagccatgga gtgtctgcaa ggtgaccttc
     3301 gtggacatgc gagacaactg tggagagggt gtgcagaccc gaaaagtaag gtgcatgcag
     3361 aatacagcag atggcccttc tgaacatgtg gaagactacc tgtgtgaccc agaggatatg
     3421 cccctgggct ctagagaatg taaactacca tgccctgagg actgtgtgat atccgagtgg
     3481 gggccatgga cccagtgttc tttgccttgc aatccaagtg gttcgaggca aaggtcagca
     3541 gatcccatca gacagcccgc tgatgaagga agagcgtgcc ctgatgctgt ggagaaagag
     3601 ccctgtaacc tgaacaaaaa ctgctaccgc tatgactata atgtcacaga ctggagtaca
     3661 tgtcagctaa gtgagaaggc ggtctgtggg aacggcatta aaacaaggat gttggactgt
     3721 gttcgaagtg atggcaagtc cgttgaccta aagtactgtg aagagcttgg gctggaaaag
     3781 aactggcaaa tgaacagttc ctgcacagtg gaatgccctt tgaactgtca gctttctgac
     3841 tggtctcctt ggtcagaatg ttcgcaaaca tgtggactca caggaaaaat gatacgaaga
     3901 cgaaccgtaa cccagccctt tcaaggtgat gggaggccct gcccttctct gatggaacaa
     3961 tccaagcctt gcccagtgaa gccatgctac cggtggcaat atggccagtg gtctccatgc
     4021 caagttcagg aggcccagtg tggagaagga accaggacac ggaatatttc ttgtgtcgtg
     4081 agtgatggct cagctgatga cttcagcaaa gcggtggatg aagagttctg tgctaacatc
     4141 gagctcatca tagatggtaa taaacaaata gttctggagg aaacctgcac ccagccctgc
     4201 ccaggtgact gttatttgaa tgactggtct tcatggagtc tgtgtcagct gacctgtgtg
     4261 aatggtgagg atcttggctt tggtggaata caggtccgat ccagagcagt gattatacaa
     4321 gaactggaga atcaacacct gtgcccagag cagatattag aaacaaaatc atgtgatgat
     4381 ggacaatgct atgaatacaa gtggatggca agtgcttgga agggctcttc tcgaacagtc
     4441 tggtgtcaaa ggtcagatgg tgtaaatgta acaggaggct gcttggtggt gagccagcct
     4501 gatgctgaca ggtcttgtaa cccaccctgt agtcaacccc actcatactg tagtgagatg
     4561 aaggcatgcc gctgtgaaga agggtacact gaagtcatgt cctctaatag cacccttgag
     4621 caatgcacac ttatccctgt ggtggtgatt cccactgtgg aagataaaag agatgtgaaa
     4681 accagtcggg cagttcaccc aacgcaaccc tccagtaacc cagcaggacg gggcaggaca
     4741 tggtttctac agccatttgg gccagatggg agactaaaga cctgggttta tggtgtcgca
     4801 gctggggcat ttgtgctgtt agtcttcatt gtctccatga tttatctagc gtgcaaaaag
     4861 ccaaagaaac cccaaagacg gcagaacaac cgcctcaaac ctttaacctt agcatatgat
     4921 ggagacgcgg acatgtaa
//
