LOCUS       NM_001009693            3586 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus thyroid hormone receptor associated protein 3
            (Thrap3), mRNA.
ACCESSION   NM_001009693 XM_233523
VERSION     NM_001009693.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3586)
  AUTHORS   Horiuchi,K., Kawamura,T., Iwanari,H., Ohashi,R., Naito,M.,
            Kodama,T. and Hamakubo,T.
  TITLE     Identification of Wilms' tumor 1-associating protein complex and
            its role in alternative splicing and the cell cycle
  JOURNAL   J Biol Chem 288 (46), 33292-33302 (2013)
   PUBMED   24100041
REFERENCE   2  (bases 1 to 3586)
  AUTHORS   Lande-Diner,L., Boyault,C., Kim,J.Y. and Weitz,C.J.
  TITLE     A positive feedback loop links circadian clock factor CLOCK-BMAL1
            to the basic transcriptional machinery
  JOURNAL   Proc Natl Acad Sci U S A 110 (40), 16021-16026 (2013)
   PUBMED   24043798
REFERENCE   3  (bases 1 to 3586)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 3586)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 3586)
  AUTHORS   Heyd,F. and Lynch,K.W.
  TITLE     Phosphorylation-dependent regulation of PSF by GSK3 controls CD45
            alternative splicing
  JOURNAL   Mol Cell 40 (1), 126-137 (2010)
   PUBMED   20932480
REFERENCE   6  (bases 1 to 3586)
  AUTHORS   Ito,M., Okano,H.J., Darnell,R.B. and Roeder,R.G.
  TITLE     The TRAP100 component of the TRAP/Mediator complex is essential in
            broad transcriptional events and development
  JOURNAL   EMBO J 21 (13), 3464-3475 (2002)
   PUBMED   12093747
REFERENCE   7  (bases 1 to 3586)
  AUTHORS   Ge,K., Guermah,M., Yuan,C.X., Ito,M., Wallberg,A.E.,
            Spiegelman,B.M. and Roeder,R.G.
  TITLE     Transcription coactivator TRAP220 is required for PPAR gamma
            2-stimulated adipogenesis
  JOURNAL   Nature 417 (6888), 563-567 (2002)
   PUBMED   12037571
REFERENCE   8  (bases 1 to 3586)
  AUTHORS   Kang,Y.K., Guermah,M., Yuan,C.X. and Roeder,R.G.
  TITLE     The TRAP/Mediator coactivator complex interacts directly with
            estrogen receptors alpha and beta through the TRAP220 subunit and
            directly enhances estrogen receptor function in vitro
  JOURNAL   Proc Natl Acad Sci U S A 99 (5), 2642-2647 (2002)
   PUBMED   11867769
REFERENCE   9  (bases 1 to 3586)
  AUTHORS   Naar,A.M., Beaurang,P.A., Zhou,S., Abraham,S., Solomon,W. and
            Tjian,R.
  TITLE     Composite co-activator ARC mediates chromatin-directed
            transcriptional activation
  JOURNAL   Nature 398 (6730), 828-832 (1999)
   PUBMED   10235267
REFERENCE   10 (bases 1 to 3586)
  AUTHORS   Ito,M., Yuan,C.X., Malik,S., Gu,W., Fondell,J.D., Yamamura,S.,
            Fu,Z.Y., Zhang,X., Qin,J. and Roeder,R.G.
  TITLE     Identity between TRAP and SMCC complexes indicates novel pathways
            for the function of nuclear receptors and diverse mammalian
            activators
  JOURNAL   Mol Cell 3 (3), 361-370 (1999)
   PUBMED   10198638
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088415.1.
            
            On Jan 13, 2005 this sequence version replaced XM_233523.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088415.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3586
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..3586
                     /gene="Thrap3"
                     /note="thyroid hormone receptor associated protein 3"
                     /db_xref="GeneID:313591"
                     /db_xref="RGD:1306129"
     exon            1..54
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            55..141
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            142..295
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..3014
                     /gene="Thrap3"
                     /note="trap150; thyroid hormone receptor-associated
                     protein complex 150 kDa component"
                     /codon_start=1
                     /product="thyroid hormone receptor-associated protein 3"
                     /protein_id="NP_001009693.1"
                     /db_xref="GeneID:313591"
                     /db_xref="RGD:1306129"
                     /translation="MSKTNKSKSGSRSSRSRSASRSRSRSFSKSRSRSRSVSRSRKRR
                     LSSRSRSRSYSPAHNRERNHPRVYQNRDFRGHNRGYRRPYYFRGRNRGFYPWGQYNRG
                     GYGNYRSNWQNYRQAYSPRRGRSRSRSPKRRSPSPRSRSHSRNSDKSSSDRSRRSSSS
                     RSSSNHSRVESSKRKSTKEKKSSSKDSRPSQAAGDNQGDEAKEQTFSGGTSQDIKGSE
                     SSKPWPDATTYGTGSASRASVSDLSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPP
                     LSNASQMGSSMSGGAGYQSGAHQGPFDHGSGSLSPSKKSPVGKSPPATGSAYGSSQKE
                     ESAASGGAAYTKRYLEEQKTENGKDKEQKQTNTDKEKLKEKGGFSDADVKMKSDPFAP
                     KTDTEKPFRGSQSPKRYKLRDDFEKKMADFHKEEMDEQDKDKCKGRKEPEFDDEPKFI
                     SKVIAGASKNQEEEKSGKWESLHAGKEKQRKAEELEEEPFTERSRKEERGGSKRSESG
                     HRGFVPEKNFRVTAYKAVQEKSSSPPPRKTSESRDKLGNKGDFSSGKSSFSITREAQV
                     NVRMDSFDEDLARPSGLLAQERKLCRDLVHSNKKEQEFRSIFQHIQSAQSQRSPSELF
                     AQHIVTIVHHVKEHHFGSSGMTLHERFTKYLKRGNEQEAAKTKKSPEIHRRIDISPST
                     FRKHGLTHEELKSPREPGYKAEGKYKDDPVDLRLDIERRKKHKERDLKRGKSRESVDS
                     RDSSHSRERSTEKTEKTHKGSKKQKKHRRARDRSRSSSSSSQSSHSYKAEEYPEEAED
                     REESTTGFDKSRLGTKDFVGPNERGGRARGTFQFRARGRGWGRGNYSGNNNNNSNNDF
                     QKRSREEEWDPEYTPKSKKYYLHDDREGEGSDKWMSRGRGRGAFPRGRGRFMFRKSST
                     SPKWAHDKFSGEEGEIEDDESGTENREEKDSLQPSAE"
     exon            296..1198
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1894
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            1895..2067
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2068..2179
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..2264
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2265..2452
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2453..2648
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2649..2792
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
     exon            2793..3562
                     /gene="Thrap3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgggccggtt gtgccgttgc gagactgcag ctgtagtcgc ttcggccggt caagagttat
       61 accctgactg taaattggag aagccagtag tgctgctggt gtttttttgg agacagttga
      121 agttgaatca ttaattctaa ggtttaaact cttccaagat gtcaaaaaca aacaaatcca
      181 agtctgggtc tcgctcttct cggtcaagat cagcatccag atctcggtct cgttcgtttt
      241 caaagtctcg atcccgaagc cgatctgtct ctcgttcaag gaagcgcagg ctgagttcta
      301 ggtctcgttc cagatcatac tctccagctc ataacagaga aaggaatcac cccagagtat
      361 atcagaatcg agatttccga ggtcacaaca gaggctacag aaggccctat tacttccgtg
      421 gacgaaaccg aggcttttat ccatggggcc agtataaccg aggtggctat ggaaattacc
      481 gttctaattg gcagaactac cggcaagcat acagccctcg tcggggccga tcccgatctc
      541 ggtcccccaa gagaaggtcc ccttcaccaa ggtccaggag ccattctagg aactcggata
      601 agtcatcctc tgacaggtca agacgttctt cgtcctcccg gtcgtcctcc aaccacagca
      661 gagttgaatc atctaaacga aagtctacaa aagagaaaaa gtcctcttcc aaggatagcc
      721 ggccatctca ggcagctggt gataaccagg gagatgaggc taaggagcag acattttctg
      781 gaggcacctc tcaagatata aaagggtctg agagctcaaa gccatggcca gatgctacca
      841 cctatggcac tggttctgca tcacgggcct cggtttctga tctgagtccc cgggagagaa
      901 gcccagctct caaaagcccc ctccagtctg tggtggttag gcgaaggtca ccacgcccta
      961 gccctgtgcc caaacctagt cctcctcttt ctaatgcatc ccagatgggc tcatctatgt
     1021 caggcggtgc tggatatcag tctggagcac accaaggtcc gtttgaccat ggctctgggt
     1081 ctttgagtcc atccaaaaag agccctgtgg gtaagagtcc accagccact ggctctgcat
     1141 atggttcatc tcagaaagag gagagcgctg cttcgggagg agcagcctac acaaaaaggt
     1201 atctggaaga gcagaagacg gagaatggga aggataagga gcagaaacaa acaaatactg
     1261 ataaagagaa gctgaaggag aaagggggct tctctgatgc tgatgtcaaa atgaaatctg
     1321 atccatttgc tcccaagacg gacactgaga agcccttccg aggcagccag tcacccaaaa
     1381 ggtataagct ccgggatgac tttgagaaaa agatggctga cttccacaag gaggagatgg
     1441 atgaacaaga taaggacaaa tgtaagggaa ggaaggaacc tgagtttgat gatgagccca
     1501 aatttatatc taaagtcata gccggtgcaa gcaaaaacca ggaggaagag aagtcaggca
     1561 agtgggagag cctgcatgca gggaaggaaa agcagaggaa agcagaggag ctggaggagg
     1621 agcctttcac agagagatcc cgaaaggagg aacgtggagg gtccaagagg agcgaaagtg
     1681 ggcacagggg ctttgtgcca gaaaagaatt tccgggtgac tgcatacaag gcggtccagg
     1741 agaaaagttc atcgcctccc ccaaggaaga cctctgagag ccgtgacaag ctgggaaaca
     1801 aaggagactt ttcctcaggg aagtcttcct tttccattac tcgggaggcc caggtcaatg
     1861 tccggatgga ctccttcgat gaggaccttg cacgacccag tggcttattg gctcaggaac
     1921 gaaagctttg tcgggatcta gtccatagca acaaaaagga gcaggaattc cgttccattt
     1981 tccagcacat acagtcagct cagtcgcagc gtagcccctc agaattgttt gcccagcaca
     2041 tagtgaccat tgttcatcat gttaaagagc atcactttgg atcctctgga atgacattgc
     2101 atgagcgctt tactaaatac ctaaagagag ggaatgaaca agaagcagct aaaactaaga
     2161 aaagcccaga gatacacagg aggatagaca tttcccccag tacattcaga aagcatggtt
     2221 tgactcatga ggaattgaaa agtccacggg aacctggcta caaggctgaa ggaaagtaca
     2281 aagatgatcc tgttgatctt cgccttgata ttgaacgccg taaaaaacat aaggagagag
     2341 atcttaagcg aggtaaatca agagagtcgg tggattccag agactctagc cactcaagag
     2401 aaagatcaac tgaaaagaca gagaaaaccc acaaaggatc aaagaagcag aagaagcacc
     2461 gcagagcaag agaccggtct aggtcctcct cgtcctcttc ccagtcatct cactcctaca
     2521 aagcagagga gtaccctgag gaagcagagg acagggagga gagcaccaca ggttttgaca
     2581 aatccagatt ggggaccaaa gactttgtgg gtccgaatga aagaggcggc agagctcggg
     2641 gaaccttcca atttcgagca agagggagag gttggggcag aggaaactat tctggtaaca
     2701 ataacaacaa cagcaacaat gatttccaaa agagaagccg ggaagaagaa tgggatcccg
     2761 agtacacacc caagagcaag aagtattact tgcatgacga ccgggaaggc gagggcagcg
     2821 acaagtggat gagccgaggc cgcggccgag gagccttccc ccgggggcgg ggccggttca
     2881 tgttcaggaa atccagtacc agccccaagt gggcccatga caagttcagt ggggaggagg
     2941 gggagattga agacgatgag agtgggacag agaacagaga agaaaaggac agtttacaac
     3001 cttcagctga gtaggggcca ctcttgatgg agcccttgcc ggggagaaag gcactgggag
     3061 aggctggtcg agctaaacaa ggagcctcaa gaagatcctg aaaaccccac cccacaaccc
     3121 actagccaca cagaatccca ctacagcaga gtgtgtccct ggtgctgtct cactggacag
     3181 gacgctgcca ccgagcctac atcaggccca tgtttccagc agagcacact gggctcccgc
     3241 tgctgtttgt gtggggtggg gcagggtggg gagaaggatg cgatgcttgg actttgtgtt
     3301 ggttttgtcg tcccatcccc actccacccc caattagaaa ccaagttttc ttaatttcat
     3361 ttcatttgga actaaatggg aatttggttt tcaatctctt cctgtcctga gtttttaaaa
     3421 gtccttatat ttttcttttt tccttttttt tggggggggg tgggggatat gtagtaatat
     3481 tagcataaag attttaattt gggcaacttt gattcctaag agaaaacaaa gcatgtgaat
     3541 aaaaattgaa gtgttcacct caaaaaaaaa aaaaaaaaaa aaaaaa
//
