LOCUS       NM_001106059            2115 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus THO complex subunit 3 (Thoc3), mRNA.
ACCESSION   NM_001106059 XM_001068440 XM_237957
VERSION     NM_001106059.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2115)
  AUTHORS   Chi B, Wang Q, Wu G, Tan M, Wang L, Shi M, Chang X and Cheng H.
  TITLE     Aly and THO are required for assembly of the human TREX complex and
            association of TREX components with the spliced mRNA
  JOURNAL   Nucleic Acids Res 41 (2), 1294-1306 (2013)
   PUBMED   23222130
REFERENCE   2  (bases 1 to 2115)
  AUTHORS   Grolimund L, Aeby E, Hamelin R, Armand F, Chiappe D, Moniatte M and
            Lingner J.
  TITLE     A quantitative telomeric chromatin isolation protocol identifies
            different telomeric states
  JOURNAL   Nat Commun 4, 2848 (2013)
   PUBMED   24270157
REFERENCE   3  (bases 1 to 2115)
  AUTHORS   Boyne JR, Colgan KJ and Whitehouse A.
  TITLE     Recruitment of the complete hTREX complex is required for Kaposi's
            sarcoma-associated herpesvirus intronless mRNA nuclear export and
            virus replication
  JOURNAL   PLoS Pathog 4 (10), e1000194 (2008)
   PUBMED   18974867
REFERENCE   4  (bases 1 to 2115)
  AUTHORS   Cheng H, Dufu K, Lee CS, Hsu JL, Dias A and Reed R.
  TITLE     Human mRNA export machinery recruited to the 5' end of mRNA
  JOURNAL   Cell 127 (7), 1389-1400 (2006)
   PUBMED   17190602
REFERENCE   5  (bases 1 to 2115)
  AUTHORS   Masuda S, Das R, Cheng H, Hurt E, Dorman N and Reed R.
  TITLE     Recruitment of the human TREX complex to mRNA during splicing
  JOURNAL   Genes Dev 19 (13), 1512-1517 (2005)
   PUBMED   15998806
REFERENCE   6  (bases 1 to 2115)
  AUTHORS   Guo S, Hakimi MA, Baillat D, Chen X, Farber MJ, Klein-Szanto AJ,
            Cooch NS, Godwin AK and Shiekhattar R.
  TITLE     Linking transcriptional elongation and messenger RNA export to
            metastatic breast cancers
  JOURNAL   Cancer Res 65 (8), 3011-3016 (2005)
   PUBMED   15833825
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474032.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001068440.1, XM_237957.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168852.1, EV775026.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2115
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..2115
                     /gene="Thoc3"
                     /note="THO complex subunit 3"
                     /db_xref="GeneID:290519"
                     /db_xref="RGD:1311669"
     exon            1..304
                     /gene="Thoc3"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1093
                     /gene="Thoc3"
                     /note="THO complex 3"
                     /codon_start=1
                     /product="THO complex subunit 3"
                     /protein_id="NP_001099529.1"
                     /db_xref="GeneID:290519"
                     /db_xref="RGD:1311669"
                     /translation="MAVPAAVLGPSALSQSGPGSMAPWCSVSSGPSRYVLGMQELFRG
                     HSKTREFPAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSV
                     DQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENINICWSPDGQTIAVGN
                     KDDVVTFIDAKTHRSKAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQ
                     SINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSH
                     DGKMLASASEDHFIDIAEVETGDKLWEVQCESPTFTVAWHPKRPLLAFACDDKDGKYD
                     SSREAGTVKLFGLPNDS"
     exon            305..461
                     /gene="Thoc3"
                     /inference="alignment:Splign:2.1.0"
     exon            462..666
                     /gene="Thoc3"
                     /inference="alignment:Splign:2.1.0"
     exon            667..828
                     /gene="Thoc3"
                     /inference="alignment:Splign:2.1.0"
     exon            829..929
                     /gene="Thoc3"
                     /inference="alignment:Splign:2.1.0"
     exon            930..2115
                     /gene="Thoc3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccagcttc cggcgcgcga tccttgcgga gagggccatg gcggttcccg ccgctgtcct
       61 ggggccctct gccctcagcc agagcggccc cgggtcgatg gcgccctggt gctcggtgag
      121 cagtggcccg tctcgttatg tgctcgggat gcaggagttg ttccgaggcc acagcaagac
      181 tcgtgagttc ccggcgcaca gtgccaaggt gcactcggtg gcctggagct gcgacggtcg
      241 tcgcttggcc tcgggatctt tcgacaagac tgccagcgtg ttcttgctgg agaaggaccg
      301 gctggtcaag gaaaacaact accgtggaca tggggatagc gtggaccagc tctgctggca
      361 tccaagcaac cctgaccttt ttgtcaccgc atctggagat aaaaccattc gcatctggga
      421 tgtgaggact acaaaatgca tcgccactgt gaacacgaaa ggggagaaca ttaacatctg
      481 ctggagtccc gacgggcaga ccattgcagt gggcaacaag gatgatgtcg tgacctttat
      541 tgacgccaag acgcaccgtt ccaaagcgga ggagcagttc aagtttgagg tcaatgagat
      601 ctcgtggaac aacgacaaca acatgttctt cctgaccaat ggcaacggct gtatcaacat
      661 cctcagctac ccagaactga agcctgtgca gtccatcaat gcccaccctt ctaactgcat
      721 ctgtatcaag tttgacccca tggggaaata ctttgccaca ggaagtgcgg atgccttggt
      781 cagcctctgg gacgttgacg agctagtgtg cgtgcggtgc ttttccagac tagattggcc
      841 tgtgaggacc ctcagtttta gccacgatgg gaaaatgctg gcgtcggctt cggaggacca
      901 tttcattgac atagctgaag tagagacagg agacaagctg tgggaggtgc agtgtgagtc
      961 cccgactttc accgtggctt ggcaccccaa gaggcctctg ctggcttttg cctgcgacga
     1021 caaagatggc aagtacgaca gcagccggga ggctgggacc gtgaagctct tcgggcttcc
     1081 caatgactcc tgagaggaca tagctggaag gaagaggacg acgggcggac tattcaggct
     1141 tcctaatgac tggacctgac ggggagaggg ggctgggcgc aagccttcct tttgtatagt
     1201 tccgtgtggt cttttgggct ttgggcaccc taaatgtttg taaatggcat acattacaaa
     1261 aaccctttgg tcaggctgtg gtaccggagg attgaaccag ccttgcacgt ggtgagcaag
     1321 tggcccactc agccagcccc gccccactgc ctgaggtttt ttgttttttg ttttttgttt
     1381 ttttttggtg tattttgtgt taagcagtta gctaataagg actctgcaag tatgggtcat
     1441 aatctgttgt tgagggttct ctaaaggaag agaactggta gaatgtctgt ctgtctctct
     1501 cttgtctctg tgtgtccata catgggattt tatcagaatg gctgacaggc tgtggtctgg
     1561 gttgtcattc caacgacgct gccgtctcct gacggaaagg ccaaggatca gtagccgctg
     1621 agactcatct gatgcggagt cctggggaat cctagagagc tgcaatcgtc cgtcagtgtt
     1681 ggaatcctga agaagcaggc tctgtggtta ccagggaggg actccctgag cagcagggtg
     1741 gatggaccag gcagtgagag tgagggcaaa caggcagaaa gcggaagcct tttgtgtgac
     1801 tttttataca ctgccaccag catgtgtccc aggtttccgg tggctcttcc tacctcagat
     1861 gatcaagatt tctctcaggt gtgccctgct ggttgggttt cagtggtttc cagacgctgc
     1921 agtcaagttg acagccaaga ttgcccacca catgcccagc gtggcatgcc ctttgggagt
     1981 gccctgtgtt ctgggtttta atatggcagt ttgttgctta ggcagtacct acttagaggg
     2041 agggcagcat agggatggga tttttaaaaa cagctttgag aactgagcat tcattaaagc
     2101 cggctttcgt tatga
//
