LOCUS       NM_001013966            1145 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus tRNA-histidine guanylyltransferase 1-like
            (Thg1l), mRNA.
ACCESSION   NM_001013966 XM_220327
VERSION     NM_001013966.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1145)
  AUTHORS   Hickey,F.B., Corcoran,J.B., Docherty,N.G., Griffin,B.,
            Bhreathnach,U., Furlong,F., Martin,F., Godson,C. and Murphy,M.
  TITLE     IHG-1 promotes mitochondrial biogenesis by stabilizing PGC-1alpha
  JOURNAL   J Am Soc Nephrol 22 (8), 1475-1485 (2011)
   PUBMED   21784897
  REMARK    GeneRIF: IHG-1 increases mitochondrial biogenesis by promoting
            PGC-1alpha-dependent processes, potentially contributing to the
            pathogenesis of renal fibrosis
REFERENCE   2  (bases 1 to 1145)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
REFERENCE   3  (bases 1 to 1145)
  AUTHORS   Hyde,S.J., Eckenroth,B.E., Smith,B.A., Eberley,W.A., Heintz,N.H.,
            Jackman,J.E. and Doublie,S.
  TITLE     tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl
            transferase, shares unexpected structural homology with canonical
            5'-3' DNA polymerases
  JOURNAL   Proc Natl Acad Sci U S A 107 (47), 20305-20310 (2010)
   PUBMED   21059936
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087596.1.
            
            On Apr 20, 2005 this sequence version replaced XM_220327.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087596.1, SRR8487231.93814.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1145
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q21"
     gene            1..1145
                     /gene="Thg1l"
                     /note="tRNA-histidine guanylyltransferase 1-like"
                     /db_xref="GeneID:303067"
                     /db_xref="RGD:1359513"
     exon            1..204
                     /gene="Thg1l"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..910
                     /gene="Thg1l"
                     /EC_number="2.7.7.79"
                     /codon_start=1
                     /product="probable tRNA(His) guanylyltransferase"
                     /protein_id="NP_001013988.1"
                     /db_xref="GeneID:303067"
                     /db_xref="RGD:1359513"
                     /translation="MWAFSTARIGSPLAATSVTLRRCLRLGVAMAKSKFEYVRDFEVD
                     DTCLPHCWVVVRLDGRNFHRFAEKHNFAKPNDSRALHLMTKCAQTVMQELEDIVIAYG
                     QSDEYSFVFRKRSNWFKRRASKFMTLVASQFASSYVFYWRDYFEDQPLLYPPGFDGRV
                     VLYPSNQTLKDYLSWRQADCHINNLYNTVFWALIQQSGLTPVQAQQRLKGTLTADKNE
                     ILFSEFHINYNNEPHMYRKGTVLVWQKVNEVRTQEIRLPAEMEGEKMAVTRTRTKLVA
                     LNCDLIGDAFWKEHPEILEGED"
     exon            205..381
                     /gene="Thg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            382..551
                     /gene="Thg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            552..640
                     /gene="Thg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            641..748
                     /gene="Thg1l"
                     /inference="alignment:Splign:2.1.0"
     exon            749..1120
                     /gene="Thg1l"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttccctatgg ctaatgtggg ctttcagcac agctaggatc ggcagtcctt tggccgctac
       61 ttccgttact ttaagacggt gcttgaggtt gggggtggct atggccaaga gcaagtttga
      121 gtacgtgcgg gattttgagg ttgacgacac atgcctgccc cactgctggg ttgtggtgcg
      181 tctggacggc cggaattttc accggtttgc tgagaagcac aactttgcca aacctaatga
      241 cagtcgagct ctccatctga tgaccaaatg tgcccagaca gtaatgcagg agctggagga
      301 cattgtgatt gcgtatggac agagtgatga gtacagcttt gtgtttagga agagaagcaa
      361 ttggttcaaa agaagagcca gtaagttcat gactctcgtg gcctcccagt tcgcctccag
      421 ttacgtgttt tactggcgtg attactttga ggaccagccc cttctgtatc ccccaggatt
      481 tgatggaaga gtcgtgttgt atcctagcaa ccagactttg aaggactacc tcagctggcg
      541 gcaggcagac tgtcacatca ataatcttta taatacagtt ttctgggccc ttatccagca
      601 gtctggacta acaccagtgc aggcccagca gagactaaag ggaactctga cagcagacaa
      661 gaatgagatt ctgttctccg agttccacat caactacaac aatgaaccac atatgtacag
      721 gaaagggaca gtgttagtgt ggcaaaaggt gaatgaagtc aggacacaag aaattaggct
      781 gccagcagaa atggaagggg aaaagatggc cgtgactcgg accagaacca agctggtggc
      841 tttgaactgt gatctcattg gggatgcctt ctggaaggaa cacccagaga ttctggaggg
      901 agaggactga tcttgcgtgg tgcagttctg gcatacttaa tcacgcaggg ctacccaagt
      961 ctctccaacc tcaggtggcc cgagcatccc tggccccaag agcactgtca ggaggactgg
     1021 ggttgggtgg agacagacga aggagggatg tgtgggggcg gcgtatcttg ttctgcttaa
     1081 gcagaatacc ttaaaaaaaa aaaaaaaaaa catgttagaa aaaaaaaaaa aaaaaaaaaa
     1141 aaaaa
//
