LOCUS       NM_001271480            3110 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus thymocyte selection associated family member 2
            (Themis2), mRNA.
ACCESSION   NM_001271480 XM_001064217 XM_575925
VERSION     NM_001271480.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3110)
  AUTHORS   Lesourne,R., Zvezdova,E., Song,K.D., El-Khoury,D., Uehara,S.,
            Barr,V.A., Samelson,L.E. and Love,P.E.
  TITLE     Interchangeability of Themis1 and Themis2 in thymocyte development
            reveals two related proteins with conserved molecular function
  JOURNAL   J Immunol 189 (3), 1154-1161 (2012)
   PUBMED   22732588
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Aug 29, 2022 this sequence version replaced NM_001271480.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.8060.1,
                                           SRR26360176.705187.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-109               JAXUCZ010000005.1  150290235-150290343 c
            110-250             JAXUCZ010000005.1  150286269-150286409 c
            251-661             JAXUCZ010000005.1  150283019-150283429 c
            662-1731            JAXUCZ010000005.1  150278773-150279842 c
            1732-1879           JAXUCZ010000005.1  150276661-150276808 c
            1880-3110           JAXUCZ010000005.1  150275094-150276324 c
FEATURES             Location/Qualifiers
     source          1..3110
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..3110
                     /gene="Themis2"
                     /gene_synonym="RGD1561016"
                     /note="thymocyte selection associated family member 2"
                     /db_xref="GeneID:500561"
                     /db_xref="RGD:1561016"
     exon            1..109
                     /gene="Themis2"
                     /gene_synonym="RGD1561016"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..1989
                     /gene="Themis2"
                     /gene_synonym="RGD1561016"
                     /codon_start=1
                     /product="protein THEMIS2"
                     /protein_id="NP_001258409.1"
                     /db_xref="GeneID:500561"
                     /db_xref="RGD:1561016"
                     /translation="MEPVPLQDFASSLDPASLPRVLRVCSGVYFEGSVYELFGNECCL
                     STGDLIKVTHIHLEKVVCEDPETGQTLELNPNFTGLFSTLTSLQSYRTLEDLVSAMPQ
                     NSTQCPIYFKSTQRIVTEARVVPEDQPLRLEAVEVHHGTRYARCVQASKTQEIILHLP
                     LSQKGPFWRCKPSAPQTLLQILQDPAMKGLRLTCPSLPWASVILKPQYQLQAIMHMRS
                     SVVKIPSTLEVEVEDVTASSQHIHFFKPLRLSEVLARGGPFPLSTEILEVPDGPPIFL
                     SPWMSFLRKGQRLCIYGPASSPWRVVASSKSRKVPRYFLLSGAYQGKLKRRPREFPTA
                     YDLLGALQPGRPLRVVATKDCDGNEEENPEFSFLAVGDRLEVLRSGQVCGAQGQDIDV
                     LICQRLNEQSGEEEEEEEEEGEEVEDKEQVLLPLYLSGSFVEEVNDSRRYSLADLTAQ
                     YTLPCEVKVVAKDSHHPTDPLTSFPGLRLEEKLTEPFLVVSLDSQPEMCFEIPPRWLD
                     LTVVEIEGRPGQVAGPLSVPTVEELSEAFYYGLRKLPVSGNQAPPPRPPKKQQNTQRC
                     KEGGVKARVVEPKPSCPQLERKAKTLEAFPANKSSVYSKISNKKDHKSNPQAQNSVLS
                     MKPKSSSSLGKYSTTESHLPPDPDIDDHDYEEI"
     exon            110..250
                     /gene="Themis2"
                     /gene_synonym="RGD1561016"
                     /inference="alignment:Splign:2.1.0"
     exon            251..661
                     /gene="Themis2"
                     /gene_synonym="RGD1561016"
                     /inference="alignment:Splign:2.1.0"
     exon            662..1731
                     /gene="Themis2"
                     /gene_synonym="RGD1561016"
                     /inference="alignment:Splign:2.1.0"
     exon            1732..1879
                     /gene="Themis2"
                     /gene_synonym="RGD1561016"
                     /inference="alignment:Splign:2.1.0"
     exon            1880..3110
                     /gene="Themis2"
                     /gene_synonym="RGD1561016"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agttgggtcg cgaccatgga gcctgtgccg ctgcaggact ttgcgagcag cctggacccc
       61 gcctcccttc cgcgcgtgct gcgggtctgc tccggagtct acttcgaggg ttccgtctat
      121 gagctctttg ggaatgaatg ttgcctctcc acgggggacc taatcaaggt cacccatatc
      181 cacctcgaga aggttgtgtg tgaggaccca gagacgggtc agacgttgga gctcaacccc
      241 aatttcacag gcctcttcag cacactcacc agcctgcaga gctatagaac cctggaggat
      301 ctcgtctccg ccatgcccca gaactccaca cagtgtccca tttacttcaa gtcaactcaa
      361 agaattgtca cggaggccag ggtggtgcct gaggatcagc ccctcagact tgaggccgtg
      421 gaagtacacc acgggacccg ctatgcacgc tgtgtgcagg cctcaaagac ccaggagatc
      481 atccttcatc tgcccctttc ccagaaggga cccttctgga gatgcaagcc cagtgctcca
      541 caaaccctgc tccaaatcct gcaggaccca gctatgaagg gccttaggct cacctgcccc
      601 agcctcccct gggcctctgt gatactaaag ccccagtacc agctccaggc catcatgcac
      661 atgcgcagca gcgtcgtcaa gatcccgtct actctggagg tggaggtaga agatgtcacg
      721 gcctcttccc agcacatcca cttcttcaaa ccattgcggc tgagcgaggt gctggcccgg
      781 ggaggcccct tccctctgtc cacggagatc ctggaggttc ctgatggtcc acccatcttc
      841 ctcagcccgt ggatgagctt cctacgcaaa ggccagaggc tttgcatcta tggtccagcc
      901 tcatcaccgt ggcgggttgt ggcctcaagc aagagccgaa aagttcccag atacttcttg
      961 ctctccggag cctaccaggg caagctcaaa cggaggccaa gggagttccc cacggcctat
     1021 gaccttttgg gtgctctcca gccgggccgg cccctccggg tggtggccac gaaagactgt
     1081 gatgggaacg aagaggagaa tcctgagttt tctttcttgg ctgtgggtga tcggctggag
     1141 gtgttgaggt ccggccaggt ctgtggggcc caagggcagg acatagatgt cttgatatgt
     1201 cagcggttga atgagcagtc tggggaggag gaggaggagg aagaagagga aggggaggag
     1261 gtagaggaca aagaacaggt tctgctaccc ctctacctct ctggtagctt tgtggaggag
     1321 gtaaatgaca gccgacgcta tagcctagca gatctcactg cccagtatac cctgccctgt
     1381 gaggtcaagg tggtggccaa agattcccat caccccactg accctctgac ctccttccct
     1441 ggcttgcgcc tggaggagaa gctcacagag ccctttttgg tagtaagcct ggactcccag
     1501 ccggaaatgt gcttcgagat ccctcccagg tggctggatc tgactgtggt ggagattgag
     1561 ggacggccag gccaggtggc tgggccgctg tctgtcccta cggtggagga actgtcagaa
     1621 gctttttact acggcctccg gaagctgcca gtctctggga accaagctcc tccgcctagg
     1681 cccccgaaga agcagcagaa cacacagcgc tgtaaggagg gtggcgtaaa ggctcgagtt
     1741 gtagaaccga agccatcctg cccacagctt gaacgcaagg cgaagacctt ggaagccttc
     1801 cccgcgaaca agtcaagtgt gtacagcaag atttctaaca agaaagacca caaatccaat
     1861 ccccaagcac agaattcagt gctgagtatg aaacccaaat cctcgagctc gctggggaag
     1921 tactccacca ctgagtcaca tctcccgcct gacccagata tagatgacca cgactatgaa
     1981 gaaatttgag cactttcaga aaaaacatct aggtgctcgg ggaaagccac acttcccagc
     2041 tgccgcctca cagggttacc agctaactct tggaggacct agggcagagt ctcaagggac
     2101 ttagactccg atgggcgtga gactgacact actcctgcct ctttgggttc caggtcggct
     2161 tggtcccaga aagttgcatg tgacaccctc agccttagaa cactggtgtc cagagaagcc
     2221 attcaggttc tggctcatct tgtacccatc agctgaccca ctactaggca cagagaagaa
     2281 tcagaggcca cccttcagtg ctgcctgcct ctcagtaaag agaactcagt cttcattatg
     2341 tcacccagtg taggctgccg cctttgcctg ctctgccctg tgccgggggg cagacagtat
     2401 tctcacgggg gctagaaccc agctcatgat cggtacccag taaatggcct tgtgggacta
     2461 aatgtgggca tgtgcttcca agaataaaat cctagggagg acactagttc atcaagtctg
     2521 ttagtggaac taagagagct aatttacaaa ggcagaggga ctggagagat ggttcagtgg
     2581 ttaagagcac tttggtgggt tggggattta gctcagtggt agagcgcttg cctagcaagc
     2641 acaaggccct aggttcggtc cccagctccg aaaaaaagaa aagaaaaaaa aaaagcactt
     2701 tggtgctaca gaggacccaa gttcagttcc cagcacctac atcaggtgtt tcacaactgc
     2761 ctgtaactcc agctccaggg gtcacctgct tctggacgct gtgagcactc agttcatgta
     2821 cagagccgag cccctgcaag cctccacagt tagacacaat ctaaaaattt aaagccgggg
     2881 tttgtggtgc acacctttaa cctctggagg cagaagcagg tggatatctg aattccaggc
     2941 cagcctgact tacctattta tttattaaac aaaactgaga agctggggag acccaaagtt
     3001 gtggaaatct gggtgatgct ctgacactgt taaaaagaaa gctgttaggt gacttgacga
     3061 cccaagatca tctcatggta aagcctcaga ataaaaacga cacatgcttc
//
