LOCUS       NM_001108558            1203 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus thioesterase superfamily member 5 (Them5), mRNA.
ACCESSION   NM_001108558 XM_001053262 XM_342293
VERSION     NM_001108558.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1203)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 1203)
  AUTHORS   Zhuravleva,E., Gut,H., Hynx,D., Marcellin,D., Bleck,C.K.,
            Genoud,C., Cron,P., Keusch,J.J., Dummler,B., Esposti,M.D. and
            Hemmings,B.A.
  TITLE     Acyl coenzyme A thioesterase Them5/Acot15 is involved in
            cardiolipin remodeling and fatty liver development
  JOURNAL   Mol Cell Biol 32 (14), 2685-2697 (2012)
   PUBMED   22586271
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474015.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001053262.1, XM_342293.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1203
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1203
                     /gene="Them5"
                     /gene_synonym="C2cd4d; RGD1562059"
                     /note="thioesterase superfamily member 5"
                     /db_xref="GeneID:361993"
                     /db_xref="RGD:1562059"
     exon            1..267
                     /gene="Them5"
                     /gene_synonym="C2cd4d; RGD1562059"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..894
                     /gene="Them5"
                     /gene_synonym="C2cd4d; RGD1562059"
                     /EC_number="3.1.2.2"
                     /note="C2 calcium-dependent domain-containing protein 4D;
                     C2 calcium-dependent domain containing 4D"
                     /codon_start=1
                     /product="acyl-coenzyme A thioesterase THEM5"
                     /protein_id="NP_001102028.1"
                     /db_xref="GeneID:361993"
                     /db_xref="RGD:1562059"
                     /translation="MMRTGFQGVARLVHHKALYRSPQTLPRLHLASAFGSSTDSLVAR
                     FCGEKTDLKDYALPNASWCPDMLSLYQEFLEKTKSGSWVKLPSFKSNRDHIRGLKLPF
                     GLVAASDKQDWRLFTRSIQLEGQGYEYVIFFHPSEKKSVCLFQPGPYLEGAPGFAHGG
                     SLAALMDETYSKTAYLAGEGLFTLSFNIKFKNLIPVGSLAVLDLQVEKIEDQKLYMSC
                     IAQSRDKQTVYAKSSGVFLQLQLEEEQSGEQ"
     exon            268..469
                     /gene="Them5"
                     /gene_synonym="C2cd4d; RGD1562059"
                     /inference="alignment:Splign:2.1.0"
     exon            470..608
                     /gene="Them5"
                     /gene_synonym="C2cd4d; RGD1562059"
                     /inference="alignment:Splign:2.1.0"
     exon            609..719
                     /gene="Them5"
                     /gene_synonym="C2cd4d; RGD1562059"
                     /inference="alignment:Splign:2.1.0"
     exon            720..844
                     /gene="Them5"
                     /gene_synonym="C2cd4d; RGD1562059"
                     /inference="alignment:Splign:2.1.0"
     exon            845..1203
                     /gene="Them5"
                     /gene_synonym="C2cd4d; RGD1562059"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcccagccc agtcttgcag tcttcccttc ttcagccgga gctctctgct agaagcaagc
       61 ctgtgtagga gcgcctggca ctcacttgtc ctctggagtc agccactatt tatccaagca
      121 aagcctggat cctggcactc agccatgatg agaacaggtt tccagggggt agcaagactt
      181 gtccaccaca aagctcttta cagaagcccc cagaccctgc ccagactcca cctggcctca
      241 gcgtttggat cttccacaga ttccctggtt gcaagattct gtggagagaa gacagatttg
      301 aaggattatg cccttccgaa tgccagctgg tgtccagata tgctgagcct gtaccaagaa
      361 tttctggaga aaactaaatc aggcagctgg gttaaactac cctccttcaa gtccaacaga
      421 gatcatatcc ggggccttaa gctcccattt ggactggtag ctgcctcaga caaacaggac
      481 tggcgcctct ttacaagatc catccaactg gaagggcaag gttatgagta tgtcatcttt
      541 ttccacccat ctgagaagaa gtcagtctgc cttttccagc caggccccta cctagagggg
      601 gcaccagggt ttgcccatgg agggtcactg gcagccttga tggatgagac atactctaag
      661 actgcctatc tggctggaga aggactgttc acactaagtt tcaacatcaa gttcaaaaac
      721 ttgatccccg tgggctctct ggctgtcctg gaccttcagg tagaaaagat tgaagatcag
      781 aagctctaca tgtcctgtat cgcccagagc agagacaagc agacagtgta tgccaagtcc
      841 tctggtgttt tccttcagct acaactggaa gaagaacagt ccggggagca gtgactctgc
      901 cttgaccttg atgactcaac agccacataa caaagggtcc ccaggaatca gggggcagac
      961 aagagccttt tatagttgga atcaaaatcg tccacaggcc agagatagct cagcagttaa
     1021 gaacactggc tgccatttga ttcccagtac caacatggtg gttcacagcc atcttgtaac
     1081 tcctgtccaa aggaatccaa aaccctctct tgggctccat ggactaccag gcatgcatac
     1141 ggtggtgcct tacatgcaaa ccaaacaccc atatacataa aataaattca tgttttaaac
     1201 ttt
//
