LOCUS       NM_001005564            1957 bp    mRNA    linear   ROD 11-JUN-2024
DEFINITION  Rattus norvegicus THAP domain containing 4 (Thap4), mRNA.
ACCESSION   NM_001005564 XM_343633
VERSION     NM_001005564.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1957)
  AUTHORS   Katayama,K., Ito,J., Murakami,R., Yamashita,A., Sasajima,H.,
            Narahashi,S., Chiba,J., Yamamoto,I., Fujii,W., Tochigi,Y. and
            Suzuki,H.
  TITLE     Mutation of the Thap4 gene causes dwarfism and testicular anomalies
            in rats and mice
  JOURNAL   Mamm Genome 35 (2), 149-159 (2024)
   PUBMED   38658415
  REMARK    GeneRIF: Mutation of the Thap4 gene causes dwarfism and testicular
            anomalies in rats and mice.
REFERENCE   2  (bases 1 to 1957)
  AUTHORS   De Simone,G., di Masi,A., Polticelli,F. and Ascenzi,P.
  TITLE     Human nitrobindin: the first example of an all-beta-barrel ferric
            heme-protein that catalyzes peroxynitrite detoxification
  JOURNAL   FEBS Open Bio 8 (12), 2002-2010 (2018)
   PUBMED   30524950
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1957)
  AUTHORS   Bianchetti,C.M., Bingman,C.A. and Phillips,G.N. Jr.
  TITLE     Structure of the C-terminal heme-binding domain of THAP domain
            containing protein 4 from Homo sapiens
  JOURNAL   Proteins 79 (4), 1337-1341 (2011)
   PUBMED   21387410
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081882.1.
            
            On Oct 8, 2004 this sequence version replaced XM_343633.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081882.1, SRR8487230.82825.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1957
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q36"
     gene            1..1957
                     /gene="Thap4"
                     /gene_synonym="Nb(III)"
                     /note="THAP domain containing 4"
                     /db_xref="GeneID:363291"
                     /db_xref="RGD:1359473"
     exon            1..116
                     /gene="Thap4"
                     /gene_synonym="Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..1749
                     /gene="Thap4"
                     /gene_synonym="Nb(III)"
                     /note="THAP domain-containing protein 4; ferric
                     nitrobindin"
                     /codon_start=1
                     /product="peroxynitrite isomerase THAP4"
                     /protein_id="NP_001005564.1"
                     /db_xref="GeneID:363291"
                     /db_xref="RGD:1359473"
                     /translation="MVICCAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQR
                     DNWTPTKYSFLCSEHFTKDSFSKRLEDQHRLLKPTAVPSIFHLSEKKRGAGGHGPARR
                     KTTGAMRGHTSAATGKGTIGSSLSSSDNLMAKPESRKLKRASPQDDTAPKATPGAVSQ
                     EPGQSLERTPGDQAAPLARGQEEAQVSATEADHQKASSSAADAGGADKSGISMDDFTP
                     PGSGACKFIGSLHSYSFSSKHTRERPSVPREPMDRKRLKRDIEPRCSGNSVAQSPPSS
                     SLTATPQKASQSPSAPPTDVTPKPAAEAVQSEHSDANPMSINEVILSASGACKLIDSL
                     HSYCFSARQNKSQVCCLREQVEKKNGELKSLRQRVSRSDSQVRKLREKLDELRRASLP
                     YLPYLSGLLPPSHEPPKLNPVVEPLSWMLGTWLSEPPGVGTFPTLQPFQYLEEVHISH
                     VGQPMLNFSFNSFHPETHKPMHRECGFIRLKPDTNKVAFVSAQNTGVVEVEEGEVNGQ
                     ELCVSSHSISRISFAKEPHVQQITRKFRLNSEGKLEQTVSMATTTQPMTQHLHITYKK
                     VTP"
     exon            117..1255
                     /gene="Thap4"
                     /gene_synonym="Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            1256..1415
                     /gene="Thap4"
                     /gene_synonym="Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1525
                     /gene="Thap4"
                     /gene_synonym="Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1629
                     /gene="Thap4"
                     /gene_synonym="Nb(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1929
                     /gene="Thap4"
                     /gene_synonym="Nb(III)"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggatcggag cctggcgacg ctcacgaccg aggcccgcaa tggtgatctg ctgcgcggcc
       61 gtgaactgtt ccaacaggca gggcaagggc gagaaacgcg ctgtctcctt ccacaggttt
      121 cccctaaagg actccaaacg actgatccag tggttaaaag ctgttcagag ggataactgg
      181 accccaacta agtattcatt cctctgtagt gagcatttta ccaaagacag cttctccaaa
      241 aggctagagg accagcatcg cctgctgaag cccacggctg tgccctctat tttccacctg
      301 tcagagaaga agaggggggc tggaggacat ggccctgcta ggagaaagac cacaggggcc
      361 atgaggggcc acacaagtgc agcaacaggg aaaggaacca tagggtcttc actatcttca
      421 agtgataact tgatggccaa gccagaatcc cgaaagttga agcgagcttc tccacaagat
      481 gatacagccc ccaaggccac cccgggtgct gtcagtcagg agccgggtca gtctctggaa
      541 agaactccag gtgaccaggc tgccccattg gccagaggcc aggaagaggc acaagtgtct
      601 gctacagagg ctgaccacca gaaggcttct tcctctgctg ccgacgcagg tggagcagac
      661 aagagtggca tttctatgga cgacttcaca cccccgggat ctggcgcttg caagttcatt
      721 ggctcacttc attcatatag tttctcctcc aagcacactc gagagaggcc gtctgtccct
      781 cgtgagccca tggaccgcaa gaggctgaag agagacatag agccaaggtg cagtgggaat
      841 agtgtggccc agagtccccc aagttcctca cttacagcaa cccctcaaaa ggcttcccag
      901 agcccctccg ccccacccac tgatgtaacc ccaaagccag cggcagaagc cgtgcagagt
      961 gagcacagtg atgccaatcc catgtccatc aatgaggtca tcctgtcagc ctcaggggcc
     1021 tgcaagctca tcgactccct gcactcctac tgcttctcgg ctcggcagaa caagagccag
     1081 gtatgctgcc tgcgggagca ggttgagaag aagaacggag agctaaagag ccttcggcag
     1141 agggtcagcc gatctgacag ccaggtgcgc aagctgcggg agaagctgga cgagctgaga
     1201 agagcaagtc tcccttacct cccctaccta agtggtctgc tgccccccag tcacgagcct
     1261 cccaagctga atccagtggt ggagccgttg tcctggatgc tgggtacctg gctgtcagag
     1321 ccgccgggag ttggtacctt cccaacactg caacccttcc agtacctgga ggaggtgcac
     1381 atctcccatg tgggtcagcc tatgctcaac ttctcgttca actccttcca tccagaaaca
     1441 cacaagccaa tgcacagaga atgtggcttc atccgcctca agcctgacac caacaaggtg
     1501 gccttcgtca gtgcccagaa cacaggtgtt gtggaagtgg aggagggtga agtgaatggg
     1561 caggagctgt gtgtttcatc ccattccatc tccaggatct cctttgccaa ggagccccat
     1621 gtgcagcaga tcacgcggaa attcaggctg aattctgaag gcaaacttga acagacggtc
     1681 tctatggcaa ccactacaca gccaatgact cagcatcttc acattaccta caagaaggtg
     1741 accccttaac ccggagcccc tcctagagcc tggtgaggag cctggctcct gcatctagcc
     1801 ccccagttta gtagacatgg tgtggtctca ggctctgctg acactgaagt gttgtccaga
     1861 tgttcttgta atggcataga aaaccaaata aaaggccttt atttttatgg ctgaagattt
     1921 tgaatattaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//
