LOCUS       NM_001191630            3349 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus THAP domain containing 12 (Thap12), mRNA.
ACCESSION   NM_001191630 XM_218949
VERSION     NM_001191630.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3349)
  AUTHORS   Lin,Y., Khokhlatchev,A., Figeys,D. and Avruch,J.
  TITLE     Death-associated protein 4 binds MST1 and augments MST1-induced
            apoptosis
  JOURNAL   J Biol Chem 277 (50), 47991-48001 (2002)
   PUBMED   12384512
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 4, 2021 this sequence version replaced NM_001191630.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2322095.1,
                                           SRR26643292.2845.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-151               JAXUCZ010000001.1  162414781-162414931
            152-272             JAXUCZ010000001.1  162419859-162419979
            273-380             JAXUCZ010000001.1  162422533-162422640
            381-417             JAXUCZ010000001.1  162425448-162425484
            418-3349            JAXUCZ010000001.1  162427629-162430560
FEATURES             Location/Qualifiers
     source          1..3349
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..3349
                     /gene="Thap12"
                     /gene_synonym="Prkrir"
                     /note="THAP domain containing 12"
                     /db_xref="GeneID:308845"
                     /db_xref="RGD:1309679"
     exon            1..151
                     /gene="Thap12"
                     /gene_synonym="Prkrir"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..2336
                     /gene="Thap12"
                     /gene_synonym="Prkrir"
                     /note="protein-kinase, interferon-inducible double
                     stranded RNA dependent inhibitor, repressor of (P58
                     repressor)"
                     /codon_start=1
                     /product="52 kDa repressor of the inhibitor of the protein
                     kinase"
                     /protein_id="NP_001178559.1"
                     /db_xref="GeneID:308845"
                     /db_xref="RGD:1309679"
                     /translation="MPNFCAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLE
                     DKTPDQLNKHYRLCAKHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKR
                     IKELSEDEIRTLKQKKIEETSEQEQETNSNAQNPSAEVGNQQDGNVLPLTLEEKENKE
                     YLKSLFEILILMGKQNIPLDGHEADEIPEGLFAPDNFQALLECRINSGEEVLRKRFET
                     TAVNTLFCSKTQQRQMLEICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLV
                     RFVDDAHNLREEFVGFLPYEADAEILAVKFHTTITEKWGLNMEYCRGQAYIVSSGFSS
                     KMKVVASRLLEKYPQAVYTLCSSCALNAWLAKSVPVIGVSVALGTIEEVCSFFHRSPQ
                     LLLELDNVISVLFQNSEERGKELKEICHSQWTGRHDAFEILVDLLQALVLCLDGINSD
                     TNIRWNNYIAGRAFVLCSAVTDFDFIVTIVVLKNVLSFTRAFGKNLQGQTSDVFFAAS
                     SLTAVLHSLNEVMENIEVYHEFWFEEATNLATKLDIQMKLPGKFRRAQQGNLESQLTS
                     ESYYKDALSVPTVEHIIQELKDIFSEQHLKALKCLSLVPSVMGQLKFNTSEEHHADMY
                     RSDLPNPDTLSAELHCWRIKWKHRGKDIELPSTIYEALHLPDIKFFPNVYALLKVLCI
                     LPVMKVENERYENGRKRLKAYLRNTLTDQRSSNLALLNINFDIKHDLDLMVDTYIKLY
                     TNKSELPTNNSETIENT"
     exon            152..272
                     /gene="Thap12"
                     /gene_synonym="Prkrir"
                     /inference="alignment:Splign:2.1.0"
     exon            273..380
                     /gene="Thap12"
                     /gene_synonym="Prkrir"
                     /inference="alignment:Splign:2.1.0"
     exon            381..417
                     /gene="Thap12"
                     /gene_synonym="Prkrir"
                     /inference="alignment:Splign:2.1.0"
     exon            418..3349
                     /gene="Thap12"
                     /gene_synonym="Prkrir"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgcgct gccctgacaa ggcggggagg ggagggctgg accggccggc ggccggagga
       61 ccatgccgaa cttctgcgct gcccccaact gcacacggaa gagcacgcag tctgacctgg
      121 ccttcttcag attcccgcgg gacccggcca gatgccagaa gtgggttgaa aattgtagga
      181 gagcagactt agaagataaa acacctgatc aactcaataa acattatcga ctatgtgcca
      241 aacactttga gacctctatg atctgtagaa ctagtcctta tcgcacagtt cttcgagata
      301 atgcaatacc cacaatattt gatcttacca gtcatttgaa caatccacat agcagacaca
      361 gaaaacgaat aaaagaattg agtgaagatg aaatcaggac tctgaaacag aaaaaaattg
      421 aggaaacttc tgaacaagaa caggaaacta acagcaatgc tcagaacccc agtgcagaag
      481 tggggaacca gcaggatgga aatgtgttgc ctttaaccct tgaagagaag gagaacaaag
      541 agtacctcaa atcattattt gagattctga ttctcatggg aaagcagaac atacccttgg
      601 atgggcacga ggctgacgag atcccagagg gtctctttgc tccagataac ttccaggcac
      661 tcctagagtg ccgtatcaat tctggagaag aagtcctaag gaagcgcttt gagaccacgg
      721 cggtcaacac gttattctgt tctaaaaccc agcagaggca gatgctggag atctgtgaga
      781 gctgcattcg ggaggagaca ctcagggaag tgagagactc acacttcttt tccattatca
      841 cagacgacgt ggtagacata gcaggagaag agcacctgcc cgtgctggtg aggtttgtcg
      901 atgatgctca taacctgaga gaggagtttg tgggatttct gccatatgaa gctgacgcag
      961 agattttggc tgtgaaattt cacactacaa taaccgagaa atggggattg aatatggaat
     1021 attgtcgtgg tcaggcttac attgtgtcca gtggattttc ttccaaaatg aaagttgttg
     1081 cttcaagact tttagaaaaa tatccccagg ccgtctacac cctctgttct tcctgtgcct
     1141 taaatgcatg gttggcaaag tctgtccctg tgatcggggt gtctgtggct ttaggaacca
     1201 ttgaggaagt ctgttctttt ttccatcgat caccacagct gcttttagaa cttgacaacg
     1261 taatttctgt tcttttccag aatagtgaag agcgaggtaa agaactgaag gaaatttgtc
     1321 attcacagtg gacaggcagg cacgatgcct ttgaaatctt ggtggatctc ctgcaagcac
     1381 ttgtcttatg tttagatggt ataaatagcg acacaaatat taggtggaat aactatatag
     1441 ctggacgagc gtttgtactc tgtagtgcag tgacagattt cgatttcatt gttaccattg
     1501 ttgttcttaa aaatgtgtta tcttttacga gggcctttgg gaagaatctc cagggacaaa
     1561 cctctgatgt cttcttcgca gccagcagct taactgccgt actgcactca cttaatgagg
     1621 tgatggaaaa catcgaagtt tatcatgagt tttggtttga ggaagccaca aatttagcaa
     1681 ccaaacttga cattcaaatg aagctgccag ggaagttccg gagagcccaa caaggtaacc
     1741 tggaatctca gctaacctcc gagagttact ataaagatgc tctcagtgtt ccaacagtag
     1801 agcacattat tcaggaactt aaagatattt tctctgaaca gcacctcaaa gctctgaagt
     1861 gcctgtctct ggtaccctca gtgatggggc agctcaagtt taacacatcc gaagagcacc
     1921 atgctgatat gtacagaagt gacctaccca atcctgacac gctctctgcc gagcttcact
     1981 gttggagaat caagtggaaa cacagaggaa aagatatcga gctcccgtcc accatttatg
     2041 aagccctcca tcttcctgac atcaagtttt tccctaatgt atatgctttg ctgaaggtct
     2101 tatgtattct tcctgtgatg aaagttgaga atgagcgcta tgaaaatgga cgaaagcgtc
     2161 tcaaagcata cctgcggaac actctgacag accagaggtc aagcaatttg gctttgctta
     2221 acataaattt tgatataaaa catgatttag atttaatggt ggacacatac atcaaactct
     2281 atacaaataa atcagagctt cctacaaata attcagaaac cattgaaaat acctaaaaga
     2341 ttttaaaaat ggctgttgtc ttattttgct gtttggaaga aaagctgcaa ggtatagtag
     2401 gccagttaat gacttgccat agacctccag tttaacatat caattagcta ttgggaatcc
     2461 acatatttaa atggcccctg tttgaactct catgctctca gtacctgtct gttcttccag
     2521 aagttggcat tgggagtacc aaaatgcctc tctgctagag gcactctgga aatgttttag
     2581 ttaaaagtca ttttagatct gacatcatca ctgttgatcc ggttgtcagt tattaagtta
     2641 tcaggtcttt ggaaaatgaa ttttgtgaga gaaatacatt ttataacgtg tcatgatgaa
     2701 atacaccatt gacttttgac ttggagttac aggtgtttaa aatctgtggt agcagcactt
     2761 ggaaggcaga ggcatgagga tgacatgttt taggccagcc tgcacacata gtgagaaaca
     2821 agtgaggccc ggggtggagc ttagtgtgga gctcttgcct agcatgtgca agccctaggc
     2881 tcttgcctcg gtgtggcaaa agcaaaacca acagatcagc ttgtgatggg tagtcacggg
     2941 aagtaaggac agcctcctgc gcaggttctg tcagggcaga agagcctcaa aggagcaagt
     3001 taaagtaaga atggcagagc cgggcactgg cccctcattt gattgttgct gtttacattc
     3061 ctttgctgag cccacatttt cataagcgtt ttgttattct ctctgcttgg tggagaagac
     3121 agacccagag gccatccata ataggcaact gacttgtctg ttttcttctt tttacatgat
     3181 tatgtctact gcctcatctt gatttatcag caaaacctac agaaataaat gttttgtggt
     3241 ttatcttaaa aataatacag aaaatattgc tgttattttt ggtgaataaa attaattttg
     3301 tatagtttat ttcaatctaa ataaaatgtg aattttgttt aaatttcag
//
