LOCUS       NM_001107422            1818 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus THAP domain containing 11 (Thap11), mRNA.
ACCESSION   NM_001107422 XM_001075955 XM_226417
VERSION     NM_001107422.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1818)
  AUTHORS   Yin RH, Li Y, Yang F, Zhan YQ, Yu M, Ge CH, Xu WX, Tang LJ, Wang
            XH, Chen B, Yang Y, Li JJ, Li CY and Yang XM.
  TITLE     Expansion of the polyQ repeats in THAP11 forms intranuclear
            aggregation and causes cell G0/G1 arrest
  JOURNAL   Cell Biol Int 38 (6), 757-767 (2014)
   PUBMED   24677642
  REMARK    GeneRIF: expansion of the polyglutamine in THAP11 forms
            intracellular aggregation and is toxic in PC12 cells, suggesting a
            putative role of THAP11 in polyglutamine disease.
REFERENCE   2  (bases 1 to 1818)
  AUTHORS   Gervais V, Campagne S, Durand J, Muller I and Milon A.
  TITLE     NMR studies of a new family of DNA binding proteins: the THAP
            proteins
  JOURNAL   J Biomol NMR 56 (1), 3-15 (2013)
   PUBMED   23306615
  REMARK    Review article
REFERENCE   3  (bases 1 to 1818)
  AUTHORS   Zhu CY, Li CY, Li Y, Zhan YQ, Li YH, Xu CW, Xu WX, Sun HB and Yang
            XM.
  TITLE     Cell growth suppression by thanatos-associated protein 11(THAP11)
            is mediated by transcriptional downregulation of c-Myc
  JOURNAL   Cell Death Differ 16 (3), 395-405 (2009)
   PUBMED   19008924
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001075955.1, XM_226417.3.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1818
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..1818
                     /gene="Thap11"
                     /note="THAP domain containing 11"
                     /db_xref="GeneID:307806"
                     /db_xref="RGD:1310268"
     exon            1..1818
                     /gene="Thap11"
                     /inference="alignment:Splign:2.1.0"
     CDS             219..1145
                     /gene="Thap11"
                     /codon_start=1
                     /product="THAP domain-containing protein 11"
                     /protein_id="NP_001100892.1"
                     /db_xref="GeneID:307806"
                     /db_xref="RGD:1310268"
                     /translation="MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAG
                     VSGCFSTFQPTTGHRLCSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARR
                     RQQQQQQQQQQQQQQQQQQQQQQQQSPSSSTAQTAQLQPNLVSASAAVLLTLQAAVDS
                     SQAPGTVVPAPTTSSGDDVKPIDLTVQVEFAAAEGAAAAAAASELEAATAGLEAAECT
                     LGPQLVVVGEEGFPDTGSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSI
                     RHLRLTEAKLREELREKDRLLAMAVIRKKHGM"
ORIGIN      
        1 gaagcgcagg cgggctgccg ggtgggtagc gcggcgcggg cggtccgcaa gcatattctg
       61 ggcacggggc ctccgctcgg gaggactgcg ccgggcggca atagtgagag acctctaaga
      121 gcctcgcgcg gcaccgcccg tcgaggagct gaagtggggg ccagacccgg ccgtcgaaga
      181 gctcaagagg ccggtgggcc gggccgcgcg tcgcagccat gcctggcttt acgtgctgcg
      241 taccgggctg ctacaacaac tcacaccgag acaaggcgct gcacttctac acgtttccca
      301 aggacgctga actgcggcgc ctctggctca agaacgtgtc ccgtgctggc gtcagtgggt
      361 gcttctccac cttccagccc accacgggcc accgtctctg cagcgttcac ttccagggcg
      421 gccgcaagac ctacacggtg cgcgttccca ccattttccc gctgcgtggc gtcaatgagc
      481 gcaaagtagc tcggagacct gcgggagctg cggcagcccg ccgtaggcag cagcagcagc
      541 agcagcaaca acaacaacag cagcagcagc agcaacagca gcaacagcag cagcagcagt
      601 ctccgtcctc ctccactgcc cagactgccc agttgcagcc gaatctggtg tctgcctctg
      661 cggccgtgct tcttactctt caggccgccg tagacagcag ccaggctcct ggaaccgtgg
      721 ttccagcgcc cactacttcc tcgggagatg atgtgaagcc catcgacctt acagtgcaag
      781 tagagtttgc agctgctgaa ggggcagccg ccgctgccgc cgcatcagag ctagaggctg
      841 ctacagctgg gctggaggcc gctgagtgca ctctgggccc tcagctggtg gtagtagggg
      901 aagagggctt ccctgatact ggctccgacc actcatactc tttgtcgtcc ggtaccacgg
      961 aggaggagct cctgcgcaag ctgaatgagc agcgggacat cttggccctg atggaagtga
     1021 agatgaaaga gatgaagggt agcatccgcc atctgcgtct taccgaggcc aagctccgtg
     1081 aagaacttcg agagaaggat cgcctgcttg ccatggctgt catccgtaag aagcacggaa
     1141 tgtgaatggt tcctcccaga aacctgcaga attcgtgact ccttccagcc caaggaatcc
     1201 tcaggcagat gttgaactcc ccaatattct ggttgacagt gctgaggttt aggacagtgg
     1261 gacttaagct ggtcaattgg caccctcttt cgtttcctcc tgaagtagga gttggggact
     1321 tcagaatctg gtgacaccag cagttatgac tttgtctctc actccccaat ttatgttgca
     1381 gattctggtt atacaaaggc ttcagaacca ttgaacttga aacttaccct ggaggggtgc
     1441 aaatgggact cttagggact gtgggtttga gaaagcccac atcttaaggt tggccagcaa
     1501 ttgaagacag ctttgctgtg tgtagtaata agagatctca gtaacatcat ttctcctttt
     1561 catgctaccc gtttcaggtg cagcctgtga ttctgatgga gactagttga tctgcgcctc
     1621 tgcctgttag gacctctcta cccagaaggt catttatcag aggactctgg gtgacttgct
     1681 gatggagatc cagctgacca gggacttagg tttatctcgt tatgtttgct actggttaca
     1741 aattctattt tctgtacaat tagactgaag ttttcactgt gtttggcaaa acaaattaaa
     1801 caagaaagta aggttttt
//
