LOCUS       NM_001394729            1242 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus TDP-glucose 4,6-dehydratase (Tgds), mRNA.
ACCESSION   NM_001394729
VERSION     NM_001394729.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 1242)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643288.54618.1,
                                           SRR26643429.49427.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-102               JAXUCZ010000015.1  101602617-101602718 c
            103-169             JAXUCZ010000015.1  101600597-101600663 c
            170-238             JAXUCZ010000015.1  101598069-101598137 c
            239-329             JAXUCZ010000015.1  101596981-101597071 c
            330-472             JAXUCZ010000015.1  101591816-101591958 c
            473-571             JAXUCZ010000015.1  101589499-101589597 c
            572-631             JAXUCZ010000015.1  101587358-101587417 c
            632-675             JAXUCZ010000015.1  101586649-101586692 c
            676-841             JAXUCZ010000015.1  101585712-101585877 c
            842-900             JAXUCZ010000015.1  101584719-101584777 c
            901-998             JAXUCZ010000015.1  101583616-101583713 c
            999-1242            JAXUCZ010000015.1  101582227-101582470 c
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q24"
     gene            1..1242
                     /gene="Tgds"
                     /note="TDP-glucose 4,6-dehydratase"
                     /db_xref="GeneID:306164"
                     /db_xref="RGD:1306544"
     exon            1..102
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..1084
                     /gene="Tgds"
                     /EC_number="4.2.1.46"
                     /codon_start=1
                     /product="dTDP-D-glucose 4,6-dehydratase"
                     /protein_id="NP_001381658.1"
                     /db_xref="GeneID:306164"
                     /db_xref="RGD:1306544"
                     /translation="MSAASREERSGPPGSFAKRVLVTGGAGFIASHVIVSLVEDYPNY
                     MIINLDKLDYCASLKNLEPVSNKQNYKFIQGDICDSHFVKRLFESEKIDIVLHFAAQT
                     HVDLSFVRAFEFTYVNVYGTHVLVNTAYEARVEKFIYVSTDEVYGGSLDQEFDESSPK
                     QPTNPYASSKAAAECFVQSYWERYKFPVVITRSSNVYGPHQYPEKVIPKFISLLQHDR
                     KCCIHGSGLQRRNFLYAADVVEAFLTVLTKGEPGEIYNIGTNFEMSVVQLAKELIQLI
                     KETNSDSETERWVDYVSDRPHNDMRYPMKSEKIHSLGWKPKVPWEEGIKKTVEWYREN
                     FHNWKNAEKALEPFPVQPPFI"
     exon            103..169
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            170..238
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            239..329
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            330..472
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            473..571
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            572..631
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            632..675
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            676..841
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            842..900
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            901..998
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1242
                     /gene="Tgds"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccacggag ctgaagatgt cggctgcgag ccgggaggag cgctctggtc ctcccggcag
       61 ctttgcgaag cgggtcctgg tgaccggggg tgctggtttc attgcatccc atgtgattgt
      121 ctccttagta gaagattatc ccaactatat gatcataaac ctagacaagc tggattactg
      181 tgcaagcttg aagaatctgg agcctgtttc taacaagcaa aactacaagt tcatacaggg
      241 tgacatctgt gattctcact ttgtgaagcg gctgtttgaa tcggagaaaa tagacatagt
      301 cctacacttt gctgcacaga ctcatgtaga tctttcattc gtccgtgcct ttgagtttac
      361 gtatgtcaat gtttatggta ctcatgttct ggtaaatact gcttatgaag ccagagtgga
      421 gaaattcatt tacgtcagca cagatgaagt atatggaggc agtcttgatc aggagtttga
      481 cgagtcgtca cccaaacaac ctacaaaccc ctatgcctca tccaaagcag ccgctgagtg
      541 ctttgtgcag tcctactggg aacgatacaa gttcccagtt gtcatcacta gaagcagcaa
      601 cgtgtatgga ccacatcagt atccagaaaa ggttattcca aaattcatat ctttgctaca
      661 gcacgacagg aaatgctgta ttcacgggtc agggcttcag agaaggaact tcctttacgc
      721 cgccgatgtg gtggaggcct ttctcactgt cctcacaaag ggagagccag gcgaaatcta
      781 caacatcggg accaactttg agatgtcagt ggtccagctt gcgaaagagt tgatacagct
      841 gatcaaagag accaattcag actctgaaac agagaggtgg gtggactacg taagtgacag
      901 acctcataat gacatgagat acccaatgaa gtctgaaaag attcacagct taggatggaa
      961 gcccaaagtg ccgtgggaag aaggaatcaa gaagacagtt gagtggtacc gagagaattt
     1021 tcacaactgg aagaatgcag aaaaggcatt agaacccttt ccagtccagc caccatttat
     1081 ataactgcca gttgcagaga agaggacacc agcgcacctc agccagtgac acagtcaagt
     1141 gcctgaatga agtcttcttt cctgggctgg gcgatgccct cagcatagat cgcgtgcagt
     1201 catcggcatg ggcatcagca ttcaccattg gtcgagagct ca
//
