LOCUS       NM_001398653            1120 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus TCF3 fusion partner (Tfpt), transcript variant 2,
            mRNA.
ACCESSION   NM_001398653 XM_006228037
VERSION     NM_001398653.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1120)
  AUTHORS   Chen,L., Cai,Y., Jin,J., Florens,L., Swanson,S.K., Washburn,M.P.,
            Conaway,J.W. and Conaway,R.C.
  TITLE     Subunit organization of the human INO80 chromatin remodeling
            complex: an evolutionarily conserved core complex catalyzes
            ATP-dependent nucleosome remodeling
  JOURNAL   J Biol Chem 286 (13), 11283-11289 (2011)
   PUBMED   21303910
REFERENCE   2  (bases 1 to 1120)
  AUTHORS   Watanabe,S. and Peterson,C.L.
  TITLE     The INO80 family of chromatin-remodeling enzymes: regulators of
            histone variant dynamics
  JOURNAL   Cold Spring Harb Symp Quant Biol 75, 35-42 (2010)
   PUBMED   21502417
  REMARK    Review article
REFERENCE   3  (bases 1 to 1120)
  AUTHORS   Bhattacharya,S., Guo,H., Ray,R.M. and Johnson,L.R.
  TITLE     Basic helix-loop-helix protein E47-mediated p21Waf1/Cip1 gene
            expression regulates apoptosis of intestinal epithelial cells
  JOURNAL   Biochem J 407 (2), 243-254 (2007)
   PUBMED   17617061
  REMARK    GeneRIF: results implicate p21Cip1 as an anti-apoptotic protein and
            suggest a role for polyamines in the regulation of p21Cip1 via the
            transcription repressor E47
REFERENCE   4  (bases 1 to 1120)
  AUTHORS   Franchini,C., Fontana,F., Minuzzo,M., Babbio,F. and Privitera,E.
  TITLE     Apoptosis promoted by up-regulation of TFPT (TCF3 fusion partner)
            appears p53 independent, cell type restricted and cell density
            influenced
  JOURNAL   Apoptosis 11 (12), 2217-2224 (2006)
   PUBMED   17041757
REFERENCE   5  (bases 1 to 1120)
  AUTHORS   Boosen,M., Vetterkind,S., Koplin,A., Illenberger,S. and Preuss,U.
  TITLE     Par-4-mediated recruitment of Amida to the actin cytoskeleton leads
            to the induction of apoptosis
  JOURNAL   Exp Cell Res 311 (2), 177-191 (2005)
   PUBMED   16229834
  REMARK    GeneRIF: Amida translocates to the cytoplasm and is recruited to
            actin filaments by Par-4, resulting in enhanced induction of
            apoptosis.
REFERENCE   6  (bases 1 to 1120)
  AUTHORS   Gan,Y., Taira,E., Irie,Y., Fujimoto,T. and Miki,N.
  TITLE     Arrest of cell cycle by amida which is phosphorylated by Cdc2
            kinase
  JOURNAL   Mol Cell Biochem 246 (1-2), 179-185 (2003)
   PUBMED   12841360
  REMARK    GeneRIF: overexpression of Amida inhibited cell growth
REFERENCE   7  (bases 1 to 1120)
  AUTHORS   Gan,Y., Taira,E., Irie,Y., Tanaka,H., Ichikawa,H., Kumamaru,E. and
            Miki,N.
  TITLE     Amida predominantly expressed and developmentally regulated in rat
            testis
  JOURNAL   Biochem Biophys Res Commun 288 (2), 407-412 (2001)
   PUBMED   11606057
  REMARK    GeneRIF: Amida is involved in spermatogenesis and may play an
            important role in development of testicular germ cells.
REFERENCE   8  (bases 1 to 1120)
  AUTHORS   Irie,Y., Yamagata,K., Gan,Y., Miyamoto,K., Do,E., Kuo,C.H.,
            Taira,E. and Miki,N.
  TITLE     Molecular cloning and characterization of Amida, a novel protein
            which interacts with a neuron-specific immediate early gene product
            arc, contains novel nuclear localization signals, and causes cell
            death in cultured cells
  JOURNAL   J Biol Chem 275 (4), 2647-2653 (2000)
   PUBMED   10644725
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 21, 2021 this sequence version replaced XM_006228037.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22399492.862364.1,
                                           SRR22399481.760962.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-360               JAXUCZ010000001.1  74502994-74503353
            361-619             JAXUCZ010000001.1  74503796-74504054
            620-690             JAXUCZ010000001.1  74507347-74507417
            691-760             JAXUCZ010000001.1  74511932-74512001
            761-967             JAXUCZ010000001.1  74512082-74512288
            968-1120            JAXUCZ010000001.1  74512614-74512766
FEATURES             Location/Qualifiers
     source          1..1120
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..1120
                     /gene="Tfpt"
                     /gene_synonym="Amida"
                     /note="TCF3 fusion partner"
                     /db_xref="GeneID:85423"
                     /db_xref="RGD:620839"
     exon            1..360
                     /gene="Tfpt"
                     /gene_synonym="Amida"
                     /inference="alignment:Splign:2.1.0"
     CDS             338..1087
                     /gene="Tfpt"
                     /gene_synonym="Amida"
                     /note="isoform 2 is encoded by transcript variant 2; TCF3
                     fusion partner homolog; protein amida; TCF3 (E2A) fusion
                     partner (in childhood leukemia)"
                     /codon_start=1
                     /product="TCF3 fusion partner homolog isoform 2"
                     /protein_id="NP_001385582.1"
                     /db_xref="GeneID:85423"
                     /db_xref="RGD:620839"
                     /translation="MELEQREGTMAAVGFEEFSAPPGSELALPPLFGGHILESELETE
                     VEFVSGGLGDSGLRERDEEEEAARGRRRRQRELNRRKYQALGRRCREIEQVNERVLNR
                     LHQVQRITRRLQQERRFLMRVLDSYGDDYRDSQFTIVLEDDGSQGTDVPTPGNVENEP
                     PEKEGLSPPQRTTATLDPSSPAPGEGPSGRKRRRAPRAASSLTPELAPVQIKVEEDFG
                     FEADEALDSSWVSRGPDKLLPYPTLASPPFD"
     exon            361..619
                     /gene="Tfpt"
                     /gene_synonym="Amida"
                     /inference="alignment:Splign:2.1.0"
     exon            620..690
                     /gene="Tfpt"
                     /gene_synonym="Amida"
                     /inference="alignment:Splign:2.1.0"
     exon            691..760
                     /gene="Tfpt"
                     /gene_synonym="Amida"
                     /inference="alignment:Splign:2.1.0"
     exon            761..967
                     /gene="Tfpt"
                     /gene_synonym="Amida"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1120
                     /gene="Tfpt"
                     /gene_synonym="Amida"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attagcagcc gcctcgcggg atggcgacag ggagagctgg gatgtaagta gggttcaggg
       61 aactcatacg ccgccgtgag tctgttaagc ggagaaccgc tttggctcgt cgacactgcg
      121 agaagacagg aacaaagaag ttgacaacat agacgatcgg tggaggcgct agagaataag
      181 tcaaaggctt caaacctcaa tttggagtcg ggtgaaaacg aaggtggtgg gtaggaaact
      241 aattcccagg tttcctgtgt cgcaaggcct gatgggacag gtagttttgc gcacggctcc
      301 tcccttctga gacttcagta gtctcctgac cagagaaatg gagttggaac agagagaagg
      361 gaccatggca gccgtgggct ttgaagagtt ctcagcgcca ccaggctcag agctggctct
      421 gcctcccttg tttggtggcc acatcctaga aagtgagcta gagacagaag tggaatttgt
      481 gtccggtggt ctgggcgatt caggactccg ggagcgggat gaagaggaag aggcagcccg
      541 gggtcgcagg cgtcgccaac gggaattaaa ccgtagaaag taccaggcac taggtcggcg
      601 ctgccgggag atcgagcagg tgaatgagcg agtcttaaac aggctccatc aggtgcaaag
      661 gataactcgg agactccagc aggagcgcag attcctcatg cgagtgctgg actcatacgg
      721 ggatgactac cgggatagcc agttcaccat tgtgttggag gatgatggca gccaaggcac
      781 tgatgtccct accccaggca atgttgagaa tgaacctcca gagaaagagg gactttcccc
      841 accacaaagg acaactgcaa ccctagaccc cagcagccca gcccctggcg aggggcccag
      901 tgggcggaag aggcggcggg caccacgagc agcatcttca ttgactccag aactggcccc
      961 agtgcagatt aaggtcgagg aagactttgg ctttgaagca gatgaggcct tggattcaag
     1021 ttgggtttcc cgagggccag acaaattgct accctaccct accctagcta gcccaccctt
     1081 tgactaaccc tgtctcccca ataaacagat tccccatgta
//
