LOCUS       NM_001012144            1922 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus trafficking from ER to golgi regulator (Tfg),
            mRNA.
ACCESSION   NM_001012144 XM_340980
VERSION     NM_001012144.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1922)
  AUTHORS   Peotter JL, Pustova I, Lettman MM, Shatadal S, Bradberry MM,
            Winter-Reed AD, Charan M, Sharkey EE, Alvin JR, Bren AM, Oie AK,
            Chapman ER, Salamat MS and Audhya A.
  TITLE     TFG regulates secretory and endosomal sorting pathways in neurons
            to promote their activity and maintenance
  JOURNAL   Proc Natl Acad Sci U S A 119 (40), e2210649119 (2022)
   PUBMED   36161950
  REMARK    GeneRIF: TFG regulates secretory and endosomal sorting pathways in
            neurons to promote their activity and maintenance.
REFERENCE   2  (bases 1 to 1922)
  AUTHORS   Kanadome T, Shibata H, Kuwata K, Takahara T and Maki M.
  TITLE     The calcium-binding protein ALG-2 promotes endoplasmic reticulum
            exit site localization and polymerization of Trk-fused gene (TFG)
            protein
  JOURNAL   FEBS J 284 (1), 56-76 (2017)
   PUBMED   27813252
REFERENCE   3  (bases 1 to 1922)
  AUTHORS   Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk
            SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni
            N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider
            J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA,
            Pelletier L, Aloy P, Hill DE, Vidal M and Roth FP.
  TITLE     Pooled-matrix protein interaction screens using Barcode Fusion
            Genetics
  JOURNAL   Mol Syst Biol 12 (4), 863 (2016)
   PUBMED   27107012
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1922)
  AUTHORS   Witte K, Schuh AL, Hegermann J, Sarkeshik A, Mayers JR, Schwarze K,
            Yates JR 3rd, Eimer S and Audhya A.
  TITLE     TFG-1 function in protein secretion and oncogenesis
  JOURNAL   Nat Cell Biol 13 (5), 550-558 (2011)
   PUBMED   21478858
REFERENCE   5  (bases 1 to 1922)
  AUTHORS   Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H,
            Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff
            S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksoz E, Droege A,
            Krobitsch S, Korn B, Birchmeier W, Lehrach H and Wanker EE.
  TITLE     A human protein-protein interaction network: a resource for
            annotating the proteome
  JOURNAL   Cell 122 (6), 957-968 (2005)
   PUBMED   16169070
REFERENCE   6  (bases 1 to 1922)
  AUTHORS   Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y,
            Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H and Sugano S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
REFERENCE   7  (bases 1 to 1922)
  AUTHORS   Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S,
            Bono H, Okazaki Y and Hayashizaki Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC078947.1.
            
            On Feb 11, 2005 this sequence version replaced XM_340980.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078947.1, SRR8487227.108465.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1922
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q12"
     gene            1..1922
                     /gene="Tfg"
                     /note="trafficking from ER to golgi regulator"
                     /db_xref="GeneID:360709"
                     /db_xref="RGD:1309751"
     exon            1..215
                     /gene="Tfg"
                     /inference="alignment:Splign:2.1.0"
     exon            216..443
                     /gene="Tfg"
                     /inference="alignment:Splign:2.1.0"
     CDS             260..1456
                     /gene="Tfg"
                     /note="TRK-fused gene protein; protein TFG-like"
                     /codon_start=1
                     /product="protein TFG"
                     /protein_id="NP_001012144.1"
                     /db_xref="GeneID:360709"
                     /db_xref="RGD:1309751"
                     /translation="MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVF
                     RGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQV
                     KYLRRELIELRNKVNRLLDSLEPPGEPGPSTSIPENDTVDGREEKPAASDSSGKQSTQ
                     VMAASMSAFDPLKNQDEINKNVMSAFGLTDDQVSGPPSAPTEDRSGTPDSIASSSSAA
                     HPAAGQPQQPPYAGAQTQAGQIEGQMYQQYQQQAGYSAQQPQAPPQQYGIQYSASYSQ
                     QTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASTYPPQTYTTQTSQP
                     ANYTVPPGSQPGMAPSQPGAYQPRPGFTPSPASTMAPPSTGANPYARNRPPFGQGYTQ
                     PGPGYR"
     exon            444..527
                     /gene="Tfg"
                     /inference="alignment:Splign:2.1.0"
     exon            528..674
                     /gene="Tfg"
                     /inference="alignment:Splign:2.1.0"
     exon            675..842
                     /gene="Tfg"
                     /inference="alignment:Splign:2.1.0"
     exon            843..983
                     /gene="Tfg"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1073
                     /gene="Tfg"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1899
                     /gene="Tfg"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcccctgcg cttcccacct gccacgtacg ggaccgcggc tcttgctagg ctcgttgggt
       61 gtgtgcgatt ggccaggtcc gcgcagcctg cagctcggcg acgatcggcg gagggcggcc
      121 gggtggacgg tgtcggtagc ctccctgcga cactgcggag cccgcggcgg cctcgtagcg
      181 acccggtcag ctgaggcggc ggcctgggca agccgttttt cccctagagt tatatatata
      241 gagcatcctg gagtccacaa tgaacggaca gttggaccta agtgggaagc tgattatcaa
      301 agctcaactt ggagaagata tccggcgaat tcccattcat aatgaagaca ttacttatga
      361 tgaattagtg ctgatgatgc agcgagtatt cagaggaaag cttctgagta atgatgaagt
      421 tacaataaag tataaggatg aggatggaga tcttataaca atttttgata gttctgacct
      481 ttcctttgca attcagtgta gtagaatact gaaactgaca ttatttgtta atggccagcc
      541 aagacccctt gaatcaagtc aggtgaaata tcttcgtcga gaactgatag aacttcggaa
      601 taaagtgaat cgcttattgg acagcttaga gccgcctgga gaaccagggc cttccaccag
      661 tattcctgaa aatgatactg tggatggtag ggaagaaaag cctgctgctt ctgattcttc
      721 tgggaaacag tctactcagg ttatggcagc aagtatgtca gcttttgatc ctctaaaaaa
      781 ccaagatgaa atcaacaaaa atgtcatgtc agcatttgga ttaacagacg accaggtttc
      841 aggaccaccc agtgctccta cagaagaccg ttccggaaca cctgacagca ttgcttcttc
      901 ctcttcggca gcacacccag cagcaggtca gccacagcaa cctccctatg caggagctca
      961 gacacaagca ggtcagattg aaggtcagat gtaccaacag taccagcagc aggctggcta
     1021 cagtgcacag cagcctcagg cccctcctca gcagtacggt attcagtatt cagctagtta
     1081 cagccagcag actggacccc aacaacctca gcagttccag ggatatggcc aacaaccaac
     1141 ttcccaggca ccggctcctg ccttttctgg ccagccacaa caactgcccg ctcaaccacc
     1201 acagcagtac caggcgagca cttaccctcc acagacttac actacccaga catctcagcc
     1261 tgctaactat actgttcccc ccggctctca gcctggaatg gctccaagcc aacctggtgc
     1321 ttaccaacca agaccaggtt ttacaccatc tcctgcaagt accatggccc ctccttccac
     1381 tggggctaac ccttatgctc gtaaccgtcc tccttttggt cagggctata cccaacctgg
     1441 acctggttat cgataaggag gttcagccac actaataatg atggcttatt gcctcctaaa
     1501 agactataca atactatttt gtttcaattt gtattgtatt gaagtttaaa aatttaaaaa
     1561 gcagagcatt tttttatgat atcattgttg ctgttaattg aaaatataat ttactggaat
     1621 acaaacacaa aaagaccaaa atgaacattg tttcctcccc tgcttaaaat tgtagccgct
     1681 tcctaattat tttggaacac tactcttacc tgcgtgtaaa atgattggct ttctagcttc
     1741 ccagagaata ttaaaaagtt aggctaaggt atagccatca cacttggcta tttactatta
     1801 acatgatgta ctaaataaaa atagagccct ttgagaagat gactagacat tatgtataaa
     1861 atgtaacatt gataggctaa taaaggtgat tgaatccaaa aaaaaaaaaa aaaaaaaaaa
     1921 aa
//
