LOCUS       NM_022379               1622 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus transcription factor EC (Tfec), mRNA.
ACCESSION   NM_022379 XM_001058616 XM_342644
VERSION     NM_022379.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Fujimoto,M., Oshima,K., Shinkawa,T., Wang,B.B., Inouye,S.,
            Hayashida,N., Takii,R. and Nakai,A.
  TITLE     Analysis of HSF4 binding regions reveals its necessity for gene
            regulation during development and heat shock response in mouse
            lenses
  JOURNAL   J Biol Chem 283 (44), 29961-29970 (2008)
   PUBMED   18755693
REFERENCE   2  (bases 1 to 1622)
  AUTHORS   Kwitek,A.E., Gullings-Handley,J., Yu,J., Carlos,D.C., Orlebeke,K.,
            Nie,J., Eckert,J., Lemke,A., Andrae,J.W., Bromberg,S., Pasko,D.,
            Chen,D., Scheetz,T.E., Casavant,T.L., Soares,M.B., Sheffield,V.C.,
            Tonellato,P.J. and Jacob,H.J.
  TITLE     High-density rat radiation hybrid maps containing over 24,000
            SSLPs, genes, and ESTs provide a direct link to the rat genome
            sequence
  JOURNAL   Genome Res 14 (4), 750-757 (2004)
   PUBMED   15060019
REFERENCE   3  (bases 1 to 1622)
  AUTHORS   Zhao,G.Q., Zhao,Q., Zhou,X., Mattei,M.G. and de Crombrugghe,B.
  TITLE     TFEC, a basic helix-loop-helix protein, forms heterodimers with
            TFE3 and inhibits TFE3-dependent transcription activation
  JOURNAL   Mol Cell Biol 13 (8), 4505-4512 (1993)
   PUBMED   8336698
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 27, 2020 this sequence version replaced NM_022379.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L08812.1, SRR26643292.16802.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840111,
                                           SAMN16676809 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               JAXUCZ010000004.1  46146062-46146200   c
            140-391             JAXUCZ010000004.1  46115049-46115300   c
            392-506             JAXUCZ010000004.1  46086337-46086451   c
            507-563             JAXUCZ010000004.1  46085154-46085210   c
            564-639             JAXUCZ010000004.1  46081450-46081525   c
            640-787             JAXUCZ010000004.1  46075356-46075503   c
            788-1622            JAXUCZ010000004.1  46073605-46074439   c
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q22"
     gene            1..1622
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /note="transcription factor EC"
                     /db_xref="GeneID:26296"
                     /db_xref="RGD:3846"
     exon            1..139
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /inference="alignment:Splign:2.1.0"
     exon            140..391
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /inference="alignment:Splign:2.1.0"
     CDS             212..1165
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /note="rTFEC; TFE-C"
                     /codon_start=1
                     /product="transcription factor EC"
                     /protein_id="NP_071774.1"
                     /db_xref="GeneID:26296"
                     /db_xref="RGD:3846"
                     /translation="MTLDHRLFSQTLKRAQPLAASCMPLAEHGPRSPDSDAGCAGNPF
                     TNPLALGKEDGVVEWRLSGSILDVYSGEQGISPVNTGLMNASCPSILPMKKEIAETDT
                     RALAKERQKKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDIRWNKGTILKASVDYI
                     KWLQKEQQRARELEHRQKKLEHANRQLMLRIQELEIQARAHGLPILASLGTADFGTHI
                     TKQQTHSEKNSVGCCQQLTPSQGTSPEFYEQAVAFSDPLSHFTDLSFSAALKEEQRLD
                     GMLLSDTICPFGTDPLLSAISPAVSKASSRSSLSSEDGDEL"
     exon            392..506
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /inference="alignment:Splign:2.1.0"
     exon            507..563
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /inference="alignment:Splign:2.1.0"
     exon            564..639
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /inference="alignment:Splign:2.1.0"
     exon            640..787
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /inference="alignment:Splign:2.1.0"
     exon            788..1622
                     /gene="Tfec"
                     /gene_synonym="Tcfec"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggattccaag ctgttcagac catgcattcc tcatgaacag accccttgac ttttgcgctt
       61 atgttgaggg acgagggact atatgtggag ctgtttgcag ctgtaatgac ataacacagc
      121 tagaacccaa tcagtgctgg tccaggcaca cttagaaacc tctacgaggc ctcagcttcc
      181 aaaggctcag acacagcaag taactccttt tatgactctt gaccatcggt tgttcagcca
      241 gactctcaag agagcacagc ctctagcagc aagctgcatg cctctggcag agcatggacc
      301 caggagccca gacagtgatg ctggctgtgc aggaaaccca ttcacaaatc ctctggctct
      361 tgggaaagaa gatggcgttg tggaatggcg gttgtctggt agtattttgg atgtatatag
      421 tggcgagcag ggcatttctc cagttaacac tggtcttatg aatgcttctt gtccaagtat
      481 tctacccatg aagaaggaaa ttgcagaaac tgacactaga gctttggcaa aggagagaca
      541 gaaaaaggac aaccacaacc tcattgaaag aagaagaagg tataatatta attacagaat
      601 caaggagctt ggcactctta ttccaaagtc taatgatcct gatatacgct ggaacaaagg
      661 aaccattcta aaagcatcag tggactacat caagtggcta caaaaagaac aacagagagc
      721 ccgggagtta gaacacagac agaagaaatt agagcatgct aaccggcagc ttatgctccg
      781 cattcaggag ctagaaatac aagcacgtgc tcatggtcta ccaatcctgg cttcactcgg
      841 cacagctgac tttggtaccc acatcactaa acagcagacc cattctgaga agaactcagt
      901 aggctgttgc caacaactga ctccatccca ggggacaagc ccggagttct atgagcaagc
      961 tgtggctttc tctgatccac tgtctcactt cacagattta tcgtttagtg ctgctttgaa
     1021 agaggagcaa agattggatg gtatgctact aagtgataca atatgcccct ttgggacgga
     1081 cccgctactc tctgccattt ctcctgcagt ttccaaagcg agcagtcgaa gcagccttag
     1141 ctcagaggat ggcgatgaac tgtaagccac agacagactc aagtcatcaa ccaggaagca
     1201 gctccgtgct ggtgcttctc aatcgtggtc tgtgcttcat acctggcttt cacttaattc
     1261 tctgaaagga atgattataa gtgatggaat atctcatggg aagaagaaac atgatgctaa
     1321 agaatcattg aagatcacag tattgttgcc cactttgcct acagagttca gatttcctta
     1381 catttaattt ccctggaaag tggttcaact taataaccac tgcggtgtta ataccgtcag
     1441 agctgtgaca tcatagcata ttactggagt tacagtctct caggagactg caacatccca
     1501 ctcccctctc acttccacac cctgcctcac cttctacaac atcattttct gaagattcac
     1561 aactaagaag attgatgata atttttttcc tttgtctggt ggacatatta cctatagtca
     1621 aa
//
