LOCUS       NM_001106847            2399 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus transcription factor Dp-2 (Tfdp2), mRNA.
ACCESSION   NM_001106847 XM_001069174 XM_217232
VERSION     NM_001106847.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2399)
  AUTHORS   Zaragoza,K., Begay,V., Schuetz,A., Heinemann,U. and Leutz,A.
  TITLE     Repression of transcriptional activity of C/EBPalpha by
            E2F-dimerization partner complexes
  JOURNAL   Mol Cell Biol 30 (9), 2293-2304 (2010)
   PUBMED   20176812
REFERENCE   2  (bases 1 to 2399)
  AUTHORS   Rubin,S.M., Gall,A.L., Zheng,N. and Pavletich,N.P.
  TITLE     Structure of the Rb C-terminal domain bound to E2F1-DP1: a
            mechanism for phosphorylation-induced E2F release
  JOURNAL   Cell 123 (6), 1093-1106 (2005)
   PUBMED   16360038
REFERENCE   3  (bases 1 to 2399)
  AUTHORS   Vara,D., Bicknell,K.A., Coxon,C.H. and Brooks,G.
  TITLE     Inhibition of E2F abrogates the development of cardiac myocyte
            hypertrophy
  JOURNAL   J Biol Chem 278 (24), 21388-21394 (2003)
   PUBMED   12682052
REFERENCE   4  (bases 1 to 2399)
  AUTHORS   Nili,E., Cojocaru,G.S., Kalma,Y., Ginsberg,D., Copeland,N.G.,
            Gilbert,D.J., Jenkins,N.A., Berger,R., Shaklai,S., Amariglio,N.,
            Brok-Simoni,F., Simon,A.J. and Rechavi,G.
  TITLE     Nuclear membrane protein LAP2beta mediates transcriptional
            repression alone and together with its binding partner GCL
            (germ-cell-less)
  JOURNAL   J Cell Sci 114 (Pt 18), 3297-3307 (2001)
   PUBMED   11591818
REFERENCE   5  (bases 1 to 2399)
  AUTHORS   Trimarchi,J.M., Fairchild,B., Verona,R., Moberg,K., Andon,N. and
            Lees,J.A.
  TITLE     E2F-6, a member of the E2F family that can behave as a
            transcriptional repressor
  JOURNAL   Proc Natl Acad Sci U S A 95 (6), 2850-2855 (1998)
   PUBMED   9501179
REFERENCE   6  (bases 1 to 2399)
  AUTHORS   Wu,C.L., Zukerberg,L.R., Ngwu,C., Harlow,E. and Lees,J.A.
  TITLE     In vivo association of E2F and DP family proteins
  JOURNAL   Mol Cell Biol 15 (5), 2536-2546 (1995)
   PUBMED   7739537
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC168961.1.
            
            [WARNING] On Aug 9, 2024 this sequence was replaced by
            NM_001106847.3.
            
            On May 14, 2010 this sequence version replaced NM_001106847.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168961.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680414, SAMN06680416
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2399
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..2399
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /note="transcription factor Dp-2"
                     /db_xref="GeneID:300947"
                     /db_xref="RGD:1305814"
     exon            1..66
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            67..215
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            216..319
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             317..1474
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /note="transcription factor Dp-2 (E2F dimerization partner
                     2)"
                     /codon_start=1
                     /product="transcription factor Dp-2"
                     /protein_id="NP_001100317.2"
                     /db_xref="GeneID:300947"
                     /db_xref="RGD:1305814"
                     /translation="MIISTPQRITNSGSVLIGSPYTPAPAMVTQTHIAEAAGWVPSDR
                     KRAREFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFT
                     NASNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLE
                     IEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPAVNSTIQLPFIVI
                     NTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKIA
                     KSLVPKALEGYITDVSTGPSWLNQGLLLNSTQSVSNLDPTTGATVPQSSVNQGLCLDA
                     EVALATGQFLAPNSHQSSTAASQFSESRGETPCSFNDEEEEDEEEDPSSPE"
     exon            320..441
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            442..489
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            490..652
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            653..796
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            797..865
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            866..1017
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1184
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1290
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..2372
                     /gene="Tfdp2"
                     /gene_synonym="Tcfdp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgactgactg ccttggagcc cgcagacagt cggacatgta caattccaac tatgcaggtc
       61 ttgtgagtat agaggacaaa gacaacttgc aggagctggc tccctttctg ctcatagaaa
      121 ttagggtcag attgaggcgg tcaggtttgt gcagcaagca ctctactctc tgggtcatct
      181 ggatagccct agtagccaca tttgaaaaga aaacggtaac atttcacttg tggcctttcc
      241 agtttcaagc accaactcac caacaaagat tttaccgaaa accttagggc cagtaaatgt
      301 gaatgttgga ccccaaatga ttataagcac accacagaga attaccaatt caggaagtgt
      361 tctgattggg agtccatata cccctgcacc agcaatggtc actcagactc acatagctga
      421 ggctgctggc tgggttccca gtgatagaaa acgagctaga gaatttatag actccgattt
      481 ttcagaaagt aaacgaagca aaaaagggga caaaaatggg aaaggcttga gacatttttc
      541 aatgaaggtg tgtgagaaag ttcaacggaa aggcacaaca tcatacaatg aagtagctga
      601 tgaactggtg tctgagttta ccaatgcgag taaccatctg gcagctgact cggcttatga
      661 tcagaagaac attagacgaa gagtttatga tgctctgaat gtgctaatgg caatgaacat
      721 aatttcaaag gagaaaaaag aaatcaagtg gattgggctg cctaccaact ccgcccagga
      781 gtgccagaac ctggaaatag agaagcaaag gcggatagaa cggataaagc agaagcgggc
      841 ccagctacaa gaacttctcc ttcagcaaat tgcttttaaa aacctggtac agagaaatcg
      901 acaaaatgaa caacaaaacc agggccctcc agctgtgaat tccaccattc agctgccatt
      961 tatagtcatt aatacaagca ggaaaacagt catagactgc agcatctcca gtgacaagtt
     1021 tgaatacctc tttaattttg ataacacctt tgagatccat gatgacatag aggtactgaa
     1081 gcggatggga atgtcctttg gtctggagtc aggcaaatgc tctctggagg atctgaaaat
     1141 cgcaaaatcc ctggttccaa aagctttaga aggctatatc acagacgtct ctacaggacc
     1201 ttcttggtta aatcagggac tacttttgaa ctctacccaa tcagtttcaa atttagaccc
     1261 gaccaccggt gccactgtac cccaatcaag tgtaaaccaa gggttgtgct tggatgctga
     1321 agtggcctta gcaactgggc agttccttgc cccaaacagt caccagtcca gcactgcagc
     1381 ctctcagttt tcggagtccc gaggtgagac cccctgttca ttcaacgatg aagaggagga
     1441 agatgaagag gaggacccct cctcccctga ataaagacag gagagaactc atgtttaata
     1501 tttgatgctc atgtgtgtct ttagtgtgag ctcttgtgtt ttgaaatgat tgcttcagtc
     1561 tttgcctttg tttgcatttg tgtttagtga aaactagaga aacacaataa gcaaattaca
     1621 cgcaggctga gatgattgag atgacagttc ccatagtgtg gatgaagcgg agctgcagag
     1681 ctgtggacat cgccaacaga gcaagctttc tgaggaggta gaggccgatc tgaagagcag
     1741 tgcggtgaag ttcatttgtt ttcagggagg tggggattaa aggcccacag tgtgagcatt
     1801 tagacctcag gtggctgcaa ggagcagtat gcagtgatga cagcttctcc ctcgcctgcc
     1861 cgcccactgt ccttggtagg caagagtgaa cttggaagtc acagtggggg tctgttgtcg
     1921 cctgcgcgga gcggtgaact gctgagctgg tccaggttta gctgagcgcc tcttgcatct
     1981 gctgccttag cttctgaagg gagcaagcgc taatctttaa gtacctaggt gacacgtagg
     2041 aaattttaca ctaaactgag gtgagcatct gtcagtgcgt tggtgcatag gagttactag
     2101 gactacttct ggaagccaaa gtagaatagc atttccatgt gcattaaaaa cttcgccagc
     2161 actgcctttt gccagcattc taagtttgga gttttactga gagagaaact gtttttatag
     2221 ttttaatcaa agctatgcat tcatacagct ttttaattta caatgagaca aagaaatcaa
     2281 ttcctttgac caaattgctt gtctacagtt gtctgcagta ctgtgtgatt ttacccatgt
     2341 gcaatttgta aaaatgaacc aaatgtcatt acaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
