LOCUS       NM_001134714            3421 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus transcription factor CP2 (Tfcp2), mRNA.
ACCESSION   NM_001134714 XM_001063604
VERSION     NM_001134714.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3421)
  AUTHORS   Lee,S.J., Choi,D., Rhim,H., Choo,H.J., Ko,Y.G., Kim,C.G. and
            Kang,S.
  TITLE     PHB2 interacts with RNF2 and represses CP2c-stimulated
            transcription
  JOURNAL   Mol Cell Biochem 319 (1-2), 69-77 (2008)
   PUBMED   18629613
REFERENCE   2  (bases 1 to 3421)
  AUTHORS   Zhao,Q., Zhou,W., Rank,G., Sutton,R., Wang,X., Cumming,H.,
            Cerruti,L., Cunningham,J.M. and Jane,S.M.
  TITLE     Repression of human gamma-globin gene expression by a short isoform
            of the NF-E4 protein is associated with loss of NF-E2 and RNA
            polymerase II recruitment to the promoter
  JOURNAL   Blood 107 (5), 2138-2145 (2006)
   PUBMED   16263792
REFERENCE   3  (bases 1 to 3421)
  AUTHORS   Zhao,Q., Cumming,H., Cerruti,L., Cunningham,J.M. and Jane,S.M.
  TITLE     Site-specific acetylation of the fetal globin activator NF-E4
            prevents its ubiquitination and regulates its interaction with the
            histone deacetylase, HDAC1
  JOURNAL   J Biol Chem 279 (40), 41477-41486 (2004)
   PUBMED   15273251
REFERENCE   4  (bases 1 to 3421)
  AUTHORS   Kang,H.C., Chae,J.H., Kim,B.S., Han,S.Y., Kim,S.H., Auh,C.K.,
            Yang,S.I. and Kim,C.G.
  TITLE     Transcription factor CP2 is involved in activating mBMP4 in mouse
            mesenchymal stem cells
  JOURNAL   Mol Cells 17 (3), 454-461 (2004)
   PUBMED   15232220
REFERENCE   5  (bases 1 to 3421)
  AUTHORS   Zhou,W., Clouston,D.R., Wang,X., Cerruti,L., Cunningham,J.M. and
            Jane,S.M.
  TITLE     Induction of human fetal globin gene expression by a novel
            erythroid factor, NF-E4
  JOURNAL   Mol Cell Biol 20 (20), 7662-7672 (2000)
   PUBMED   11003662
REFERENCE   6  (bases 1 to 3421)
  AUTHORS   Zambrano,N., Minopoli,G., de Candia,P. and Russo,T.
  TITLE     The Fe65 adaptor protein interacts through its PID1 domain with the
            transcription factor CP2/LSF/LBP1
  JOURNAL   J Biol Chem 273 (32), 20128-20133 (1998)
   PUBMED   9685356
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001134714.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168176.1, SRR26643290.27878.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-451               JAXUCZ010000007.1  133537081-133537531 c
            452-603             JAXUCZ010000007.1  133521143-133521294 c
            604-680             JAXUCZ010000007.1  133520602-133520678 c
            681-786             JAXUCZ010000007.1  133518398-133518503 c
            787-893             JAXUCZ010000007.1  133515013-133515119 c
            894-1046            JAXUCZ010000007.1  133513099-133513251 c
            1047-1157           JAXUCZ010000007.1  133511136-133511246 c
            1158-1246           JAXUCZ010000007.1  133510732-133510820 c
            1247-1295           JAXUCZ010000007.1  133506655-133506703 c
            1296-1389           JAXUCZ010000007.1  133506007-133506100 c
            1390-1480           JAXUCZ010000007.1  133504955-133505045 c
            1481-1590           JAXUCZ010000007.1  133504039-133504148 c
            1591-1733           JAXUCZ010000007.1  133503531-133503673 c
            1734-1785           JAXUCZ010000007.1  133499643-133499694 c
            1786-3421           JAXUCZ010000007.1  133495577-133497212 c
FEATURES             Location/Qualifiers
     source          1..3421
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..3421
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /note="transcription factor CP2"
                     /db_xref="GeneID:315309"
                     /db_xref="RGD:1306738"
     exon            1..451
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             330..1823
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /codon_start=1
                     /product="alpha-globin transcription factor CP2"
                     /protein_id="NP_001128186.1"
                     /db_xref="GeneID:315309"
                     /db_xref="RGD:1306738"
                     /translation="MAWALKLPLADEVIESGLVQDFDASLSGIGQELGAGAYSMSDVL
                     ALPIFKQEESSLPPENENEILPFQYVLCAATSPAVKLHDETLTYLNQGQSYEIRMLDN
                     RKLGELPEINGKLVKSIFRVVFHDRRLQYTEHQQLEGWRWNRPGDRILDIDIPMSVGV
                     IDPRANPTQLNTVEFLWDPAKRTSVFIQVHCISTEFTMRKHGGEKGVPFRVQIDTFKE
                     NENGEYTEHLHSASCQIKVFKPKGADRKQKIDREKMEKRTPHEKEKYQPSYETTILTE
                     CSPWPEITYVSNSPSPGFNSSHSSFSLGEGNGSPNHQPEPPPPVTDNLLPTTTPQEAQ
                     QWLHRNRFSTFTRLFTNFSGADLLKLTRDDVIQICGPADGIRLFNALKGRMVRPRLTI
                     YVCQESLQLREQPQQPQPQQKQEDGDSNVYHAIYLEELTAVELTEKIAQLFSISPQQI
                     SQIYKQGPTGIHVLISDEMVQNFQEEACFILDTMEAETSDSYHVILK"
     exon            452..603
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            604..680
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            681..786
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            787..893
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            894..1046
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1157
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1246
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1295
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1389
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1390..1480
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1590
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..1733
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1734..1785
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
     exon            1786..3421
                     /gene="Tfcp2"
                     /gene_synonym="Tcfcp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggggccgc tcggagcggc cagcgtgctg cgcgtctctg ctttgaggct gagcggagga
       61 cgctgagcgg cgggtgggct tgggagagcc ggagtcgggc tgaggtctgg cgggacccgg
      121 cgcctcacgc ccccgagagc ggaacgggag ggtttcctgt caccggggca cctgaggagc
      181 agctagggta cagcccgtag gtcaggcttg gggtgctgcg cgaggagccg ggtttgtagt
      241 tgactactac tgtgttgtct gccgggtaga gttacagtgc gcgcctttgt accggagccg
      301 gcgcctgctg gggcagggaa ggagccggaa tggcctgggc tctgaagctg ccgctagctg
      361 acgaagtgat cgagtcgggg ctggtgcagg actttgatgc tagcctgtcg ggcattggcc
      421 aggagctggg agctggtgct tatagtatga gtgatgtcct tgcattgcct atttttaagc
      481 aagaagagtc aagtttgcct cctgaaaatg agaacgagat cctgcctttt cagtacgtcc
      541 tctgtgccgc cacctcgcca gcagtgaagc tccacgatga gaccctgacc tacctcaatc
      601 aaggacagtc ttatgaaatc cgaatgctag acaatagaaa actgggagaa ctaccggaaa
      661 tcaacggcaa gttagtgaag agcatcttcc gtgtagtgtt ccacgacagg agactgcagt
      721 acactgagca ccagcagctg gagggctgga ggtggaaccg gccaggagac aggatactgg
      781 acatcgatat cccaatgtct gtgggtgtaa ttgatcccag ggccaatcct acccagctaa
      841 acacagtgga gttcctgtgg gaccctgcaa agaggacatc tgtgtttatt caggtgcact
      901 gcatcagcac tgagttcact atgaggaagc acggtgggga aaagggggtg cccttccgag
      961 tgcagatcga taccttcaag gagaacgaga atggagagta cacggagcac ttgcactcgg
     1021 ccagctgcca gatcaaagtc ttcaagccta aaggtgcaga cagaaaacaa aagatagata
     1081 gagagaagat ggagaaacgg acgccccatg aaaaggagaa ataccagcct tcttatgaga
     1141 caaccatact cacagagtgt tctccgtggc ctgagatcac ctacgtcagc aattccccat
     1201 cgcctggctt caacagctcc cacagcagtt tctctcttgg ggaaggaaac ggctcgccca
     1261 accaccagcc agagccaccc cctccagtca cggacaacct cttgccaaca accacgcctc
     1321 aggaagccca gcagtggctg catcgaaacc ggttttccac gttcacgagg cttttcacca
     1381 acttctcagg ggcagactta ctgaaactaa ctagagatga cgtgatccaa atctgtggcc
     1441 ctgcagatgg aatccggctc ttcaacgcat tgaaaggccg gatggtgcgt ccaaggctga
     1501 ccatttatgt ctgtcaggag tcgttgcagt tgagggagca gccacagcag ccgcagccgc
     1561 agcagaagca ggaggacgga gattcaaatg tgtaccatgc tatctatcta gaggagctga
     1621 cagctgttga attaacagaa aaaattgctc agcttttcag tatttctcct cagcagatca
     1681 gccagattta caagcaaggg ccgaccggaa tccatgtgct catcagcgat gagatggtac
     1741 agaactttca ggaagaagcc tgctttattc tggacacaat ggaagcggaa accagtgata
     1801 gctatcatgt cattctcaag taggacaagc ctctcacatt cgatggctgc cgctgccttc
     1861 acctccgacg actgcccttt tgaaggggac atgactggag attaaaggtc ttcaagaacc
     1921 tggcacatct gaatgttggg gaggggggtg tccagtgcag ggcgagcagg ccctaaagtg
     1981 gaatcccaga cccttgtatt ggcccctgct gtatgacgtc ttcagatcac tggccagacg
     2041 tggagttcag tgtttcccta ggttctgggt gctggtgaca gcggtgagaa gcctggccct
     2101 tggggtttgt agagggcaga gtgataatgg gagtcgtgcg atgtcttctg gaaagaagtt
     2161 taattttgtg atatagagct ctgacatttt cctaacataa aagtgaacat ctgtcttcat
     2221 aaaaccaagc tatctctttt atatcaagtc tgttgtcagc tctgctctgt tcacaatgtg
     2281 gtgaggagaa acagaatctc tcctcacctt ctttttgaga cagggtcaca tgttcttgct
     2341 tctacctccc aagagctggg attacaagct tttgccacct gctccgtttc tgcagtgctg
     2401 ggcttgaacc cagagcacgg cctccaactg agctccagca ggcccttccc tgtgttcaga
     2461 ccgtctctgg atttctaact tggttcacct gcagtaccac aactgagagt gattttggct
     2521 aatatgtatt gggagagacc aagtgataaa tcctgtgggt ggattatctt gttttatccc
     2581 cttaataaac tcaaaacaac tggggaaaag tgacttgagg ataaggaaac gcagatgaag
     2641 tgtgggaggg ggtggattga tgccaccaga tgctaccctg tgtgcctgtg ctcaccatta
     2701 gttctttctg gggctatgct ggaaactgat ggacaagcca cagaaggagg caaacaccta
     2761 aatataacca cagtcgagtc ccatagagca gatgacaccc ggtgtcccca acctcaagca
     2821 cagagctgga ggtgagggac aagtgtgtcc gactccaagt tcattgttct tgagtgatat
     2881 cctcaagctg tttaagtaaa tggcgactct tccgtgctct tccctaccct cccctgtctt
     2941 gttttggcct agtggttttt tttttttttt taatgtaagt tttataaaaa atacattctt
     3001 tccccttcaa attcatgctg tgtttatttt tctgcctttc ttcaaataat tgtgtatctg
     3061 tgtgcatgtg cagaatttta aagcacttgg gtcctccttt ttcacatgta tagtttgttt
     3121 tggcttggtt ttccaaaaat aacatttctc tgtgtagccc cggctgtcct ggaactcaca
     3181 ctgtagacaa ggctggcctc aaactccaag atcccccttc caagtgctgg gactaaaggt
     3241 gtgcgccacc agcgtcagga cacatgtaaa gttttgccag aaatttcctt aaattttgtt
     3301 gagatgaaca aagataatta gagattctgt actgaatttg aatttgtgtg tgttttgata
     3361 aagcttagat tttttataag agttttcagt tgttgttgct gtccattaaa atcagcctgt
     3421 a
//
