LOCUS       NM_201420               1808 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus transcription factor AP-2 gamma (Tfap2c), mRNA.
ACCESSION   NM_201420 XM_342590
VERSION     NM_201420.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1808)
  AUTHORS   Kang HJ, Lee MH, Kang HL, Kim SH, Ahn JR, Na H, Na TY, Kim YN,
            Seong JK and Lee MO.
  TITLE     Differential regulation of estrogen receptor alpha expression in
            breast cancer cells by metastasis-associated protein 1
  JOURNAL   Cancer Res 74 (5), 1484-1494 (2014)
   PUBMED   24413532
REFERENCE   2  (bases 1 to 1808)
  AUTHORS   Li Q, Pan H, Guan L, Su D and Ma X.
  TITLE     CITED2 mutation links congenital heart defects to dysregulation of
            the cardiac gene VEGF and PITX2C expression
  JOURNAL   Biochem Biophys Res Commun 423 (4), 895-899 (2012)
   PUBMED   22735262
REFERENCE   3  (bases 1 to 1808)
  AUTHORS   Kuckenberg P, Buhl S, Woynecki T, van Furden B, Tolkunova E, Seiffe
            F, Moser M, Tomilin A, Winterhager E and Schorle H.
  TITLE     The transcription factor TCFAP2C/AP-2gamma cooperates with CDX2 to
            maintain trophectoderm formation
  JOURNAL   Mol Cell Biol 30 (13), 3310-3320 (2010)
   PUBMED   20404091
REFERENCE   4  (bases 1 to 1808)
  AUTHORS   Kidder BL and Palmer S.
  TITLE     Examination of transcriptional networks reveals an important role
            for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell
            maintenance
  JOURNAL   Genome Res 20 (4), 458-472 (2010)
   PUBMED   20176728
REFERENCE   5  (bases 1 to 1808)
  AUTHORS   Jager R, Schafer S, Hau-Liersch M and Schorle H.
  TITLE     Loss of transcription factor AP-2gamma/TFAP2C impairs branching
            morphogenesis of the murine mammary gland
  JOURNAL   Dev Dyn 239 (3), 1027-1033 (2010)
   PUBMED   20131354
REFERENCE   6  (bases 1 to 1808)
  AUTHORS   Maconochie M, Krishnamurthy R, Nonchev S, Meier P, Manzanares M,
            Mitchell PJ and Krumlauf R.
  TITLE     Regulation of Hoxa2 in cranial neural crest cells involves members
            of the AP-2 family
  JOURNAL   Development 126 (7), 1483-1494 (1999)
   PUBMED   10068641
REFERENCE   7  (bases 1 to 1808)
  AUTHORS   Shi D and Kellems RE.
  TITLE     Transcription factor AP-2gamma regulates murine adenosine deaminase
            gene expression during placental development
  JOURNAL   J Biol Chem 273 (42), 27331-27338 (1998)
   PUBMED   9765260
REFERENCE   8  (bases 1 to 1808)
  AUTHORS   Williamson JA, Bosher JM, Skinner A, Sheer D, Williams T and Hurst
            HC.
  TITLE     Chromosomal mapping of the human and mouse homologues of two new
            members of the AP-2 family of transcription factors
  JOURNAL   Genomics 35 (1), 262-264 (1996)
   PUBMED   8661133
REFERENCE   9  (bases 1 to 1808)
  AUTHORS   Lim LC, Fang L, Swendeman SL and Sheffery M.
  TITLE     Characterization of the molecularly cloned murine alpha-globin
            transcription factor CP2
  JOURNAL   J Biol Chem 268 (24), 18008-18017 (1993)
   PUBMED   8349681
REFERENCE   10 (bases 1 to 1808)
  AUTHORS   Trishkina,A.I. and Konopliannikov,A.G.
  TITLE     [The methods of irradiation dose fractionation and rate change used
            in studying the capacity for the postradiation repair of CFU-s
            forming splenic colonies after 8 and 12 days following bone marrow
            cell transplantation]
  JOURNAL   Radiobiologiia 32 (2), 312-316 (1992)
   PUBMED   1598407
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097260.1.
            
            On Oct 27, 2005 this sequence version replaced NM_201420.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097260.1, AY510602.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1808
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..1808
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /note="transcription factor AP-2 gamma"
                     /db_xref="GeneID:362280"
                     /db_xref="RGD:1303185"
     exon            1..263
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /inference="alignment:Splign:2.1.0"
     CDS             216..1568
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /note="activator protein 2 gamma; activating enhancer
                     binding protein 2 gamma"
                     /codon_start=1
                     /product="transcription factor AP-2 gamma"
                     /protein_id="NP_958823.2"
                     /db_xref="GeneID:362280"
                     /db_xref="RGD:1303185"
                     /translation="MLWKITDNVKYEEDCEDRHDASSNGNPRIPHLSSAGQHLYSPAP
                     PLSHTGVAEYQPPPYFPPPYQQLAYSQSADHYSHLGEAYAAAINPLHQPAPTGSQQQA
                     WPGRQSQEGSSLASHHGRSAGLIPHISGLEGSAVSSRREAYRRSDLLLPHAHALEAAG
                     LAENLGLHEMAHPIEEVQNVDDPHLLLHDQTVIRKGPISMTKNPLGLPCQKDLVGAVM
                     NPSEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGR
                     SLREKLDKIGLNLPAGRRKAAHVTLLTSLVEGEAVHLARDFAYVCEAEFPSKAVADYL
                     TRPHLGGRNEMAARKSVLLAAQQVCKEFTDLLHQDRTPNGNSRPTPVLETNIQNCLSH
                     FSLITHGFGSQAICAAVSAVQNYIKEALITIDKSYMNPGEQSPADSNKTMEKMEKHRK
                     "
     exon            264..749
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /inference="alignment:Splign:2.1.0"
     exon            750..801
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /inference="alignment:Splign:2.1.0"
     exon            802..1018
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1137
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1282
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1785
                     /gene="Tfap2c"
                     /gene_synonym="AP2-gamma; Tcfap2c"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccggtcca ccgctgcggc ctctacacac ccaccgcggc cacatctacg tgcacagcca
       61 ccgatgcgcg accagtgact gggacagcga ggcccgcgcg cggcgggggc ggcggcagac
      121 gcctggccac cgtgaccccg attgtggatt taccgctcgg ggggtggggg gagcctggat
      181 ttaactggcg actattttgg gggacgccgg acgccatgtt gtggaaaata acagataatg
      241 tcaagtatga agaggattgc gaggatcgcc acgacgcgag cagtaatggg aaccctcgca
      301 tccctcacct ctcatctgcg ggacagcatc tctacagtcc cgcgccgcct ctctcgcaca
      361 ccggggttgc agagtaccag ccgcctcctt acttcccgcc gccctaccag cagttggcat
      421 actcgcaatc cgccgatcat tactcgcact tgggagaggc ttacgctgcc gccatcaacc
      481 ccttgcacca gcctgcgccc accggcagcc agcaacaggc ctggccaggt cgacagagtc
      541 aggagggctc tagcctggct tcgcaccacg gccgctctgc aggtcttata ccccatattt
      601 cagggctgga ggggagcgcg gtgagttccc ggcgggaagc ctaccgccgt tccgatctgc
      661 tgctgcctca cgcgcacgcc ctggaagccg ccggcctggc tgagaaccta gggctgcacg
      721 agatggctca ccccattgag gaggtgcaga acgtggacga cccgcatctg cttctacacg
      781 atcagactgt cattcgcaaa ggacccattt caatgaccaa gaaccctctg ggcctccctt
      841 gccagaagga cctagttgga gcggtcatga accccagcga ggtcttctgc tccgttcctg
      901 gaagactctc cctgttgagc tccacctcga agtacaaagt aaccgtggct gaggtacaga
      961 ggcgactgtc accaccggaa tgcttgaatg cctcgctcct gggaggcgtg ctcagaagag
     1021 cgaaatccaa aaatggaggc cggtccttga gggagaagtt ggacaaaatt gggctgaacc
     1081 ttccagctgg gagacggaaa gccgcccatg tcactctcct cacatctctc gtggaaggcg
     1141 aggccgtcca cctagcccgg gactttgcct acgtctgcga agctgagttt cccagtaaag
     1201 cagtggctga ctatttaacc agaccgcatc ttgggggacg gaacgagatg gccgctagga
     1261 agagtgtgtt gttggcagca cagcaagtgt gcaaggagtt cactgacctc ctccatcaag
     1321 accgaacgcc caacgggaac agcaggccca ccccggtctt ggagacgaac atacaaaact
     1381 gcttgtctca tttcagcctg ataactcatg gctttggcag ccaggccatc tgcgcagcgg
     1441 tctctgctgt gcagaattat atcaaggagg ccctaatcac catcgacaag tcctacatga
     1501 acccgggaga gcagagtccg gctgattcca acaagacgat ggagaaaatg gaaaagcacc
     1561 ggaagtaaag tgggatcgag gaggccagaa agcggaagga gagaggaccc aagccccctc
     1621 cactggggca gcctgggaag ccctcatcgg ggcggttacc acccacctca ctttggacct
     1681 ctgccctctt ggagtctttg tgacttttcc atttaaccct ggacatgcta tcccgaagct
     1741 acttggtttg gttcttttat tcattaaaca ttgttttttt ggaaaaaaaa aaaaaaaaaa
     1801 aaaaaaaa
//
