LOCUS       NM_139037               1073 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Rattus norvegicus testis expressed 101 (Tex101), mRNA.
ACCESSION   NM_139037 XM_006228381
VERSION     NM_139037.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Endo,S., Yoshitake,H., Tsukamoto,H., Matsuura,H., Kato,K.,
            Sakuraba,M., Takamori,K., Fujiwara,H., Takeda,S. and Araki,Y.
  TITLE     TEX101, a glycoprotein essential for sperm fertility, is required
            for stable expression of Ly6k on testicular germ cells
  JOURNAL   Sci Rep 6, 23616 (2016)
   PUBMED   27005865
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  AUTHORS   Li,W., Guo,X.J., Teng,F., Hou,X.J., Lv,Z., Zhou,S.Y., Bi,Y.,
            Wan,H.F., Feng,C.J., Yuan,Y., Zhao,X.Y., Wang,L., Sha,J.H. and
            Zhou,Q.
  TITLE     Tex101 is essential for male fertility by affecting sperm migration
            into the oviduct in mice
  JOURNAL   J Mol Cell Biol 5 (5), 345-347 (2013)
   PUBMED   23969891
REFERENCE   3  (bases 1 to 1073)
  AUTHORS   Fujihara,Y., Tokuhiro,K., Muro,Y., Kondoh,G., Araki,Y., Ikawa,M.
            and Okabe,M.
  TITLE     Expression of TEX101, regulated by ACE, is essential for the
            production of fertile mouse spermatozoa
  JOURNAL   Proc Natl Acad Sci U S A 110 (20), 8111-8116 (2013)
   PUBMED   23633567
REFERENCE   4  (bases 1 to 1073)
  AUTHORS   Yoshitake,H., Yanagida,M., Maruyama,M., Takamori,K., Hasegawa,A.
            and Araki,Y.
  TITLE     Molecular characterization and expression of dipeptidase 3, a
            testis-specific membrane-bound dipeptidase: complex formation with
            TEX101, a germ-cell-specific antigen in the mouse testis
  JOURNAL   J Reprod Immunol 90 (2), 202-213 (2011)
   PUBMED   21724266
REFERENCE   5  (bases 1 to 1073)
  AUTHORS   Miranda,P.V., Allaire,A., Sosnik,J. and Visconti,P.E.
  TITLE     Localization of low-density detergent-resistant membrane proteins
            in intact and acrosome-reacted mouse sperm
  JOURNAL   Biol Reprod 80 (5), 897-904 (2009)
   PUBMED   19144954
REFERENCE   6  (bases 1 to 1073)
  AUTHORS   Yoshitake,H., Shirai,Y., Mochizuki,Y., Iwanari,H., Tsubamoto,H.,
            Koyama,K., Takamori,K., Ogawa,H., Hasegawa,A., Kodama,T.,
            Hamakubo,T. and Araki,Y.
  TITLE     Molecular diversity of TEX101, a marker glycoprotein for germ cells
            monitored with monoclonal antibodies: variety of the molecular
            characteristics according to subcellular localization within the
            mouse testis
  JOURNAL   J Reprod Immunol 79 (1), 1-11 (2008)
   PUBMED   18620756
REFERENCE   7  (bases 1 to 1073)
  AUTHORS   Yoshitake,H., Tsukamoto,H., Maruyama-Fukushima,M., Takamori,K.,
            Ogawa,H. and Araki,Y.
  TITLE     TEX101, a germ cell-marker glycoprotein, is associated with
            lymphocyte antigen 6 complex locus k within the mouse testis
  JOURNAL   Biochem Biophys Res Commun 372 (2), 277-282 (2008)
   PUBMED   18503752
REFERENCE   8  (bases 1 to 1073)
  AUTHORS   Jin,H., Yoshitake,H., Tsukamoto,H., Takahashi,M., Mori,M.,
            Takizawa,T., Takamori,K., Ogawa,H., Kinoshita,K. and Araki,Y.
  TITLE     Molecular characterization of a germ-cell-specific antigen, TEX101,
            from mouse testis
  JOURNAL   Zygote 14 (3), 201-208 (2006)
   PUBMED   16822331
REFERENCE   9  (bases 1 to 1073)
  AUTHORS   Halova,I., Draberova,L. and Draber,P.
  TITLE     A novel lipid raft-associated glycoprotein, TEC-21, activates rat
            basophilic leukemia cells independently of the type 1 Fc epsilon
            receptor
  JOURNAL   Int Immunol 14 (2), 213-223 (2002)
   PUBMED   11809740
REFERENCE   10 (bases 1 to 1073)
  AUTHORS   Halova,I., Draberova,L. and Draber,P.
  TITLE     New monoclonal antibodies to rat testicular antigen, TEC-21
  JOURNAL   Folia Biol (Praha) 47 (5), 180-182 (2001)
   PUBMED   11686435
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Nov 20, 2020 this sequence version replaced
            XM_006228381.2, NM_139037.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.1910381.1,
                                           SRR26360190.269447.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               JAXUCZ010000001.1  89387225-89387340   c
            117-221             JAXUCZ010000001.1  89385631-89385735   c
            222-362             JAXUCZ010000001.1  89385410-89385550   c
            363-548             JAXUCZ010000001.1  89384796-89384981   c
            549-680             JAXUCZ010000001.1  89383471-89383602   c
            681-1073            JAXUCZ010000001.1  89382974-89383366   c
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1073
                     /gene="Tex101"
                     /gene_synonym="Tec21"
                     /note="testis expressed 101"
                     /db_xref="GeneID:207113"
                     /db_xref="RGD:621373"
     exon            1..116
                     /gene="Tex101"
                     /gene_synonym="Tec21"
                     /inference="alignment:Splign:2.1.0"
     exon            117..221
                     /gene="Tex101"
                     /gene_synonym="Tec21"
                     /inference="alignment:Splign:2.1.0"
     CDS             158..910
                     /gene="Tex101"
                     /gene_synonym="Tec21"
                     /note="GPI-anchored surface glycoprotein; heavily
                     glycosylated protein; 36-42 kDa in RBL cells and 30-36 kDa
                     in testicular cells; testis-expressed protein 101; testis
                     expressed gene 101; testis-expressed sequence 101
                     protein-like; lipid raft-associated glycoprotein TEC-21"
                     /codon_start=1
                     /product="testis-expressed protein 101 precursor"
                     /protein_id="NP_620606.2"
                     /db_xref="GeneID:207113"
                     /db_xref="RGD:621373"
                     /translation="MGACRIQYILLVFLLIASHWTLVQNIYCEVSRTLSLEDNPSGTF
                     NWTSKAEKCNPGEFCQETVLLIKAEGTKTAILASKSCVPQGAETMTFVQYTAPPGLVA
                     ISYSNYCNDSLCNNRNNLASILQAPEPTATSNMSGARHCPTCLALEPCSSAPSMPCAN
                     GTTQCYQGRVELSGGGMDSVVHVKGCTTAIGCRLMAKMESVGPMTVKETCSYQSFLHP
                     RMAEIGASWMPTSLWVLELLLPALSLPLIYFP"
     exon            222..362
                     /gene="Tex101"
                     /gene_synonym="Tec21"
                     /inference="alignment:Splign:2.1.0"
     exon            363..548
                     /gene="Tex101"
                     /gene_synonym="Tec21"
                     /inference="alignment:Splign:2.1.0"
     exon            549..680
                     /gene="Tex101"
                     /gene_synonym="Tec21"
                     /inference="alignment:Splign:2.1.0"
     exon            681..1073
                     /gene="Tex101"
                     /gene_synonym="Tec21"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctcctgaa gcagcaccag gaacaccgca caccgtaccg gtcgccatca aagctgggtg
       61 cacagaggac acactgtggc ctgaaaaaat ttgccggctt aaaaagaaat agacagttcc
      121 caggtcctga tcagctcttc ccaaactcag agaagccatg ggagcctgcc gcatccagta
      181 catcctgctc gtctttcttc tgatagcctc gcattggact ctggtccaaa atatctactg
      241 tgaggtgagt cgaaccctga gtttggaaga caatccaagc ggtaccttta actggacttc
      301 aaaggctgag aagtgcaatc ctggagaatt ttgccaagaa acggtactgt tgattaaagc
      361 agaaggaacc aagaccgcca ttttggccag taagagctgt gtccctcaag gagcagagac
      421 gatgacattc gttcagtaca cggcccctcc tgggctggtg gccatctcct acagtaacta
      481 ctgcaatgac tccctctgca acaacaggaa caacttagct tcaatcttgc aagcaccaga
      541 gcccacagca acctccaaca tgtcaggagc ccgccactgc ccaacatgct tggccctgga
      601 gccctgttcc agtgccccct ctatgccctg tgccaatggc acaactcagt gctaccaggg
      661 aagagtcgag ctctctggag gaggcatgga ctccgtcgtg catgttaaag gctgcaccac
      721 tgcaatcggc tgcagactga tggccaagat ggagtcggtg ggacccatga cagtgaaaga
      781 gacctgtagt taccagtcat tccttcaccc ccgaatggca gagatcgggg cctcctggat
      841 gcccacctca ctgtgggtgc tggagctcct gcttccggcg ctgtcgctgc ccctcatcta
      901 cttcccttga gaggacaccg ggggtcaggg gacgccttag tcccagacac tggggccttg
      961 gctaggaggg agccttccgc ctgctgatac caatcggaag gattggggtg gggttgaaca
     1021 gaggctgcat gtgtattgga cacgaataat aaaattagtg acttgctatt caa
//
