LOCUS       NM_133396               3045 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus testis associated actin remodelling kinase 2
            (Tesk2), mRNA.
ACCESSION   NM_133396
VERSION     NM_133396.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3045)
  AUTHORS   Toshima,J., Toshima,J.Y., Takeuchi,K., Mori,R. and Mizuno,K.
  TITLE     Cofilin phosphorylation and actin reorganization activities of
            testicular protein kinase 2 and its predominant expression in
            testicular Sertoli cells
  JOURNAL   J Biol Chem 276 (33), 31449-31458 (2001)
   PUBMED   11418599
REFERENCE   2  (bases 1 to 3045)
  AUTHORS   Rosok,O., Pedeutour,F., Ree,A.H. and Aasheim,H.C.
  TITLE     Identification and characterization of TESK2, a novel member of the
            LIMK/TESK family of protein kinases, predominantly expressed in
            testis
  JOURNAL   Genomics 61 (1), 44-54 (1999)
   PUBMED   10512679
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB049402.1.
            
            On Aug 30, 2012 this sequence version replaced NM_133396.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB049402.1, BC128727.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132306
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3045              AB049402.1         2-3046
FEATURES             Location/Qualifiers
     source          1..3045
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q35"
     gene            1..3045
                     /gene="Tesk2"
                     /note="testis associated actin remodelling kinase 2"
                     /db_xref="GeneID:170908"
                     /db_xref="RGD:619984"
     exon            1..274
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            275..575
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     CDS             354..2066
                     /gene="Tesk2"
                     /EC_number="2.7.12.1"
                     /note="testicular protein kinase 2; testis-specific kinase
                     2"
                     /codon_start=1
                     /product="dual specificity testis-specific protein kinase
                     2"
                     /protein_id="NP_596887.1"
                     /db_xref="GeneID:170908"
                     /db_xref="RGD:619984"
                     /translation="MDRSKRNSIAGFPPRVERLEEFEGGGGGDGNTVQVGRVSSSSYR
                     AIISAFSRLTSLDDFTREKIGSGFFSEVFKVRHRASGQVMALKMNTLSSNRANLLKEM
                     QLMNRLSHPNILRFMGVCVHQGQLHALTEYINSGNLEQLLDSNLYLPWTVRVKLAYDI
                     AVGLSYLHFKGIFHRDLTSKNCLIKRDENGYSAVVADFGLAEKIPDASIGSEKLAVVG
                     SPFWMAPEVLRDEPYNEKADVFSYGIILCEIIARIQADPDYLPRTENFGLDYDAFQHM
                     VGDCPSDFLQLTFNCCNMDPKLRPSFEEIGKTLEEIMSRLQEEELERDRKLQPTAKGL
                     LEKVPGGKRLSSLDDKIPHKSPRPRRTIWLSRSQSDIFSRKPPRTVNVLDPYYQPRDG
                     ATHTPKVNPFSARQDLKGGKVKFFDLPSKSVISLVFDLDAPGPGTVSLADCQEPLAPS
                     SRRWRSLPGSPEFLHQACPFVGCEESLSDGPPPRLSSLKYRVREIPPFRTSALSATSA
                     HEAMDCSNPQEENGFVPRPKGTSPCSGAASEEMEVEEERPRRAPVHFSISGISLQTQG
                     EQDG"
     exon            576..697
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            698..746
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            747..893
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            894..976
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1061
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1145
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1232
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1350
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..3026
                     /gene="Tesk2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttccagctgc cttctcagtc cctgcggtga tccgcctccg ggccccgccg agcaggcggg
       61 ggaaagcagc ccagaccgca aggccatggc agtagcctcc tgctcctgcg ccgctcctgg
      121 ccctaagcaa tcgccgactt ctgcgcgagg gaccccggtc tcctccgcag gctagacagc
      181 cacgaccggg agctgctatg ctcgctctgg gccgctgcct cccttgccct ccggccggcg
      241 cagacgcccc ctccgccgct cagttgtgcc tcagtgtcac tctggaacag aagtaaaatt
      301 gaacactgat tatgcgtgga gcttcttggt gaatgcagaa gtgattgttg attatggatc
      361 ggagcaaacg gaactcgatc gcagggtttc ccccgcgtgt ggagcgtctg gaagaatttg
      421 aaggaggcgg tggaggggat gggaacactg tgcaggtggg aagagtttcg tcatcttcat
      481 atcgtgcgat tatcagtgcc ttttccagac tgacgagttt ggatgacttc acccgtgaaa
      541 aaataggatc tgggttcttc tccgaggttt tcaaggttcg gcacagagct tcagggcagg
      601 tgatggctct caagatgaac acgctgagca gtaaccgagc aaacctgctg aaggagatgc
      661 agctcatgaa cagactgtcc catcccaaca tcctcaggtt catgggtgtg tgtgtacatc
      721 aaggacagtt gcatgcactt acagagtaca tcaactctgg gaacctggag cagctgctag
      781 acagtaacct gtatttgcct tggactgtga gagtgaaact ggcctatgac atagcagtgg
      841 ggctcagcta ccttcacttc aaaggcattt tccaccggga cctcacgtcg aagaactgcc
      901 ttataaagag agatgaaaac ggttactctg cggtggtagc tgatttcggc ctggctgaga
      961 agattcctga tgctagtata gggagtgaga agctagctgt ggtgggctca cctttctgga
     1021 tggcacctga ggttctccga gatgaacctt acaatgagaa ggcagacgtg ttctcttacg
     1081 gtatcatcct ctgcgagatc atcgcccgca tccaggctga tccggactat cttccccgca
     1141 cagagaattt cgggctggat tatgatgctt tccagcacat ggtgggagac tgcccctcag
     1201 acttcctgca actcaccttc aactgctgta atatggaccc caaactgcgc ccatcctttg
     1261 aggagattgg gaagacccta gaggaaatta tgagccgctt acaggaagaa gagttggaga
     1321 gagacaggaa gctgcagccc acagctaaag gactattgga gaaagtgccc ggagggaagc
     1381 gactgagttc actggatgac aagattcccc acaagtctcc acgtccaaga cgtactatct
     1441 ggttgtctcg aagccagtca gacattttct ctcgtaagcc cccacgtaca gtcaatgtct
     1501 tggaccccta ttaccagcca cgagatggtg ctacacatac cccaaaagtc aaccctttca
     1561 gtgcacgcca agacctcaag ggtgggaagg tcaaattctt tgacctaccc agcaaatctg
     1621 ttatttccct tgtatttgac ctggatgcac cagggcctgg aactgtatct ctagctgact
     1681 gtcaggagcc tttggcccca tcttccagac ggtggcggtc tttgcctggt tcacccgagt
     1741 tcttgcatca ggcttgtcca tttgtggggt gtgaagaatc actgtctgat gggcctccac
     1801 cacgactcag tagtctcaag tacagagtaa gagagatccc accattccgg acatctgccc
     1861 tatcagctac ttcagcccat gaggccatgg attgctctaa cccccaagaa gaaaacggtt
     1921 ttgttcccag gcctaagggg accagcccat gcagtggggc tgcctctgag gagatggagg
     1981 tggaggaaga aaggccacga agagctcctg tccacttctc tatctctgga ataagcttgc
     2041 aaacccaggg agagcaggac gggtgagatg gggacaggac gagtccctgc ctctccttgg
     2101 ggatggactt tcagctgaaa ctacgtgatc cccttggtgc acagcctcac tcctccctgg
     2161 agctctcctg cacaaagcag gtagagcagg caggcgggaa aagcctggct taaaattggg
     2221 ctttctgtgc ccaatggctg caatatgaga ggtgtttcaa tagttagggc caacctaatt
     2281 ctaagtctct gaaatccagc aaggagcttt ggcccccatg gaacacagtg catgtcctag
     2341 acaggaccaa aaaacttatt tctaggctgg gctggcaggt accatgtagc tatcacccca
     2401 gttcctttcc tactccaatt ctctctcgtg ccgattctgg ggcacataag ctacaggatg
     2461 gaaactggag ttgtcgagaa ggccgttggg gcatggctgt ttcttagacc tgaagactga
     2521 ctgggacgct tcttgccagt atgtctaaga cacttgaata attgctgttt gcacttactg
     2581 tatggtcagg ccacgtcact acatctctat gcaaggggga taccaggcaa tgtggtggcc
     2641 aaggaccttt tagctaacct attcaaagac ttttccagtt gatcaatcta ttttcatatt
     2701 tataaaggag tcttaatgtt tagcctcaag actttcaacc tcggtgttgg gagtggggct
     2761 ggttttgtag gccctagggc ctgctctgtg tatgtaagca ggtgatacag cctgttagta
     2821 aatggtttat acttggactg attttctttc ctcctgtagc tggagctttg ggaacagtct
     2881 gtccttacag agccgcaata agaaataacc aaagaatgaa gttggtcaaa tattttcata
     2941 attcatttct gttgattttt ttttaaaaaa aaactttccc caaaacactt tcagattaaa
     3001 aaaataataa agttgatatt gcaggtaaaa aaaaaaaaaa aaaaa
//
